Browsing Department of Medical Biochemistry by Title
Now showing items 10-29 of 282
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An analysis of pregnancy-related mortality in the KEMRI/CDC health and demographic surveillance system in western Kenya
(Public Library of Science, 2013-07-16)Background Pregnancy-related (PR) deaths are often a result of direct obstetric complications occurring at childbirth. Methods and Findings To estimate the burden of and characterize risk factors for PR mortality, we ... -
Antibacterial activity of Garlic, Tulsi, Bitter guard and Cinnamon extracts against wound pathogens
(Journal of Scientific and Innovative Research, 2015)In the present study antibacterial properties of fruits harvested from natural medicinal plants garlic, tulsi, bitter guard and cinnamon, were explored against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, ... -
Antimicrobial activity of Eugenia jambolana seeds against foodborne isolates
(Journal of Scientific and Innovative Research 2015;, 2015)Food borne diseases encompass a wide spectrum of illnesses associated with the ingestion of food contaminated by microbes. Many medicinal plants are considered to be potential antimicrobial crude drugs as well as a source ... -
Antimicrobial Susceptibility Patterns Of Escherichea Coli Isolates Causing Urinary Tract Infections Among Pregnant Women At Kisii Teaching And Referral Hospital
(IOSR Journal of Pharmacy and Biological Sciences, 2018)Urinary tract infection is a major public health problem in terms of morbidity and financial cost and represents one of the most common diseases encountered in medical practice today with an estimated 150 million UTIs ... -
The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications
(Elsevier, 2018-12-01)Background The African Surgical Outcomes Study (ASOS) showed that surgical patients in Africa have a mortality twice the global average. Existing risk assessment tools are not valid for use in this population because the ... -
Assess Functionality of IMCI Spatial Facility Infrastructure and Policy Utilization in Trans-Nzioa County, Kenya
(Open Science Repository Medicine, 2013)Implementation of integrated management of childhood illness (IMCI), in a comprehensive and holistic approach, forms bench mark for basic child health in promoting celebration of fifth birth day for children below five ... -
Assessing levels and trends of adult mortality in Sub Saharan Africa using INDEPTH health and demographic surveillance systems
(2017)There is still a considerable dearth of knowledge regarding adult mortality and premature deaths in Sub-Saharan Africa (SSA). Attempts to measure adult mortality using censuses and cross-sectional surveys rely mainly on ... -
Assessing quality of life among gynaecological cancer patients receiving care in the palliative care unit at Kenyatta national hospital
(University of Nairobi, 2014)Quality of life (QOL) assessment among cancer patients is considered to be an important aspect in palliative care. QOL assessment helps in the identification of the physical, psychological, social and spiritual needs of ... -
An assessment of facility-based care of diabetes, hypertension, and heart failure across western Kenya
(Kenya Medical Association, 2018)Low- and middle- income countries account for three-fourths of the global non- communicable disease related mortality. In response to the increasing number of non- communicable disease diagnoses in Kenya, the government ... -
Assessment of molecular markers of anti-malarial drug resistance among children participating in a therapeutic efcacy study in western Kenya
(Springer, 2020)Background Anti-malarial drug resistance remains a major threat to global malaria control efforts. In Africa, Plasmodium falciparum remains susceptible to artemisinin-based combination therapy (ACT), but the emergence of ... -
Assessment of the relationship between digit lengths and circumferences of the waist and hip amongst Ugandans
(Maxwell Science Publishing, 2012)In human hand the second Digit (2D) and the fourth Digit (4D) present a pattern of approximate symmetry around the central axis of the third digit. Many individuals have longer 2D than 4D (2D>1) and many have longer 4D ... -
Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.
(BMC infectious diseases, 2017-04)BACKGROUND: Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of ... -
Association between Haematological parameters and Sickle cell genotypes in children with Plasmodium falciparum malaria residents in Kisumu County in Western Kenya
(Research Squire, 2020)ackground: Sickle cell disease (SCD) is a monogenic disorder due to point mutation in the β-globin gene resulting in substitution of Valine for Glutamic acid. The SCD is prevalent in P. falciparum endemic regions such as ... -
Association between Human Resource Factors and Utilization of IQCare System for Clinical Decision Support in HIV Care Clinics in Nakuru County, Kenya
(EA Journals, 2023-09-25)Electronic medical records (EMR) are computerized medical information systems that are used to collect, store, and display patient information. EMR systems can strengthen pathways of care and close gaps in patient tracking, ... -
Association between sickle cell trait and low density parasitaemia among asymptomatic and parasitaemic individuals living in P. falciparum malaria Holoendemic region of Western …
(SDI, 2008)The frequency of the mutant gene for sickle cell is widely distributed in the sub-Saharan Africa, the Middle East and the Indian subcontinent. There is epidemiologic evidence that sickle cell trait confers a survival ... -
Association between sickle cell trait and low density parasitaemia in a P. falciparum malaria holoendemic region of Western Kenya
(University of Nairobi Institute of Tropical & Infectious Diseases (UNITID), Kenya, 2012)Aims: The frequency of the mutant gene for sickle cell is widely distributed in the sub- Saharan Africa, the Middle East, and the Indian subcontinent. There is epidemiologic evidence that sickle cell trait confers a ... -
The Benefits of research partnerships to the community at KEMRI/Walter Reed Project
(Dspace, 2015)Ethical Principles on Human Subject Protection in Clinical Research revolves around Autonomy, Beneficence and Justice. Beneficence requires that the benefits to research participants are maximized as you minimize the risk ... -
beta S-haplotypes and alpha-thalassemia along the coastal belt of Kenya.
(East African medical journal, 1989)In this paper, we present data on studies of beta S-haplotypes and alpha-thalassemia gene in subjects from the indigenous population of the Coast Province of Kenya Of the 7SS patients studied, four were homozygous for beta ... -
Biochemical and molecular diagnosis of glutaric aciduria type 1 in a black South African male child: case report
(East African medical journal, 2001)Glutaric aciduria type I (GA-1) is an inborn error of metabolism caused by a deficiency of the mitochondrial enzyme glutaryl-Co enzyme A dehydrogenase. GA-1 is not uncommon amongst Caucasians but to the best of our knowledge, ... -
Bullous erythema multiforme after treatment with Malarone®, a combination antimalarial composed of atovaquone and proguanil hydrochloride
(SAGE Publications, 2008)We report on a Kenyan woman who developed bullous erythema multiforme, in association with Malarone treatment.