• A Comprehensive COVID-19 Daily News and Medical Literature Briefing to Inform Health Care and Policy in New Mexico: Implementation Study 

  LynnMarie Jarratt, Jenny Situ, Rachel D King, Estefania Montanez Ramos, Hannah Groves, Ryen Ormesher, Melissa Cossé, Alyse Raboff, Avanika Mahajan, Jennifer Thompson, Randy F Ko, Samantha Paltrow-Krulwich, Allison Price, Ariel May-Ling Hurwitz, Timothy CampBell, Lauren T Epler, Fiona Nguyen, Emma Wolinsky, Morgan Edwards-Fligner, Jolene Lobo, Danielle Rivera, Jens Langsjoen, Lori Sloane, Ingrid Hendrix, Elly O Munde, Clinton O Onyango, Perez K Olewe, Samuel B Anyona, Alexandra V Yingling, Nicolas R Lauve, Praveen Kumar, Shawn Stoicu, Anastasiya Nestsiarovich, Cristian G Bologa, Tudor I Oprea, Kristine Tollestrup, Orrin B Myers, Mari Anixter, Douglas J Perkins, Christophe Gerard Lambert (JMIR Publications Inc., Toronto, Canada, 2022)

  Background: On March 11, 2020, the New Mexico Governor declared a public health emergency in response to the COVID-19 pandemic. The New Mexico medical advisory team contacted University of New Mexico (UNM) faculty to form ...
• The Potential of Differentiation-Related Gene-1 (DRG1) as a Biomarker for Metastasis of Estrogen Receptor-Positive Breast Cancer 

  Hillary Bor , Esther N. Maina , Benson Nyambega , Kirtika Tushar Patel , Charles Ochieng’ Olwal , Walter Nalyanya and Yahaya Gavamukulya (Journal of Advances in Medicine and Medical Research(JAMMR), 2021)

  Breast cancer is major burden worldwide and the majority of breast cancers express estrogen receptors (ER) suggesting a high dependence on estrogen hormone. Age is among the major determinants of breast cancer development, ...
• Duffy Antigen/Receptor for Chemokines (DARC): Is There a Role in Prostate Cancer?. 

  Samuel B.AnyonaBS, ShiyanZhengMD,ThomasWheelerMD,MichaelIttmannMD, Teresa G.HayesMD, Martha P.MimsMD, (science direct, 2005)

  Introduction: The Duffy blood group antigens function as chemokine receptors and as receptors for several species of malarial parasites. Approximately 70% of African Americans are Duffy negative as a result of a single ...
• Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia 

  Samuel B Anyona, Prakasha Kempaiah, Evans Raballah, Gregory C Davenport, Tom Were, Stephen N Konah, John M Vulule, James B Hittner, Charity W Gichuki, John M Ong'echa, Douglas J Perkins (Wiley Subscription Services, Inc., A Wiley Company, 2012)

  In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children aged <48 months and manifests as severe malarial anemia [SMA; hemoglobin (Hb) < 6.0 g/dL]. Induction of high levels of ...
• Reduced interferon (IFN)-α conditioned by IFNA2 (− 173) and IFNA8 (− 884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all … 

  Prakasha Kempaiah, Samuel B Anyona, Evans Raballah, Gregory C Davenport, Tom Were, James B Hittner, John M Ong’echa, Douglas J Perkins (Springer-Verlag, 2012)

  Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ...
• The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis 

  Douglas J. PerkinsEmail authorTom WereSamuel AnyonaJames B. HittnerPrakasha KempaiahGregory C. DavenportJohn Michael Ong’echa (Springer, 2012)

  Plasmodium falciparum malaria is a leading global cause of morbidity and mortality of infectious disease origin. Here, we focus largely on P. falciparum malaria in sub-Saharan Africa since this geographic region bears the ...
• Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels 

  Winnie A Okeyo, Elly O Munde, Wilson Okumu, Evans Raballah, Samuel B Anyona, John M Vulule, John M Ong’echa, Douglas J Perkins & Collins Ouma (Springer, 2013)

  In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < 6.0 g/dL, with any density parasitemia] is the most common clinical manifestation of severe ...
• Integrated OMICS platforms identify LAIR1 genetic variants as novel predictors of cross-sectional and longitudinal susceptibility to severe malaria and all-cause mortality in Kenyan children 

  Angela O Achieng, Nicolas W Hengartner , Evans Raballah , Qiuying Cheng , Samuel B Anyona , Nick Lauve , Bernard Guyah , Ivy Foo-Hurwitz , John M Ong'echa , Benjamin H McMahon , Collins Ouma , Christophe G Lambert , Douglas J Perkins (PubMed, 2019)

  Severe malarial anaemia (SMA) is a leading cause of childhood mortality in holoendemic Plasmodium falciparum regions.
• 2020-04-15 DAILY UNM GLOBAL HEALTH COVID-19 BRIEFING 

  Christophe G Lambert, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Hannah Groves, Danielle Rivera, Estefania Montanez, Rachel D King, Samuel Anyona, Evans Raballah, Elly Munde, Cristian Bologa, Tudor I Oprea, Andrew S Rowland, Kristine Tollestrup, Orrin Myers, Douglas J Perkins (HSC Institutional and Academic Materials, 2020)

  NM highlights. Immigration detention centers. US outbreak perceptions. States lockdown protests. Drones sample transport. Black market antivirals. NZ eases lockdown. Germany partial reopening. Low temperature/humidity ...
• Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia 

  Evans Raballah, Samuel B Anyona, Qiuying Cheng, Elly O Munde, Ivy-Foo Hurwitz, Clinton Onyango, Caroline Ndege, Nicolas W Hengartner, Maria Andreína Pacheco, Ananias A Escalante, Christophe G Lambert, Collins Ouma, Henri C Jr T Obama, Kristan A Schneider, Philip D Seidenberg, Benjamin H McMahon, Douglas J Perkins (SAGE Publications, 2021)

  Severe malarial anemia (SMA) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions. To gain enhanced understanding of predisposing factors for SMA, we explored ...
• Assessment of molecular markers of anti-malarial drug resistance among children participating in a therapeutic efcacy study in western Kenya 

  Winnie Chebore, Zhiyong Zhou, Nelli Westercamp, Kephas Otieno, Ya Ping Shi, Sheila B. Sergent, Kelsey Anne Rondini, Samaly Souza Svigel, Benard Guyah, Venkatachalam Udhayakumar, Eric S. Halsey, Aaron M. Samuels & Simon Kariuki (Springer, 2020)

  Background Anti-malarial drug resistance remains a major threat to global malaria control efforts. In Africa, Plasmodium falciparum remains susceptible to artemisinin-based combination therapy (ACT), but the emergence of ...
• Persistence of oncogenic and non-oncogenic human papillomavirus is associated with human immunodeficiency virus infection in Kenyan women 

  Yan Tong , Philip Tonui , Aaron Ermel, Omenge Orang’o, Nelson Wong, Maina Titus, Stephen Kiptoo, Kapten Muthoka, Patrick J Loehrer and Darron R Brown (Sage, 2020)

  Objectives: Cervical cancer is caused by persistent infection with oncogenic, or “high-risk” types of human papillomaviruses, and is the most common malignancy in Kenyan women. A longitudinal study was initiated to ...
• Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling 

  Angela O Achieng, Bernard Guyah, Qiuying Cheng, John M Ong'echa, Collins Ouma, Christophe G Lambert, Douglas J Perkins (Elsevier, 2019)

  ackground: Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory recep- tor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe ...
• Epidemiological patterns and antimicrobial resistance of bacterial diarrhea among children in Nairobi City, Kenya 

  Mark Kilongosi Webale, Christine Wanjala, Bernard Guyah, Nathan Shaviya, Godwil O Munyekenye, Peter Lokamar Nyanga, Immaculate Nyaseba Marwa, Sammy Kagoiyo, Laura Nyawira Wangai, Sella K Webale, Kenny Kamau, Nicholas Kitungulu (Shahid Beheshti University of Medical Sciences, 2020)

  Aim: Determine the prevalence of enteric bacterial pathogens and their antimicrobial resistance among diarrheic children in Nairobi City, Kenya. Background: Regardless of enteric bacterial pathogens being a major cause ...
• Distribution of Biomphalaria Snails in Associated Vegetations and Schistosome Infection Prevalence Along the Shores of Lake Victoria in Mbita, Kenya: A Cross-Sectional Study 

  Sabiano O Odero, Lilian Ogonda, David Sang, Elly O Munde, Clement Shiluli, Patrick Chweya (East African Health Research Commission, 2019)

  Background: Schistosomiasis due to Schistosoma mansoni remains a major public health problem and cause of morbidity and mortality in sub-Saharan Africa despite the implementation of control programmes. More than 6 million ...
• Diagnostic dose determination and efficacy of chlorfenapyr and clothianidin insecticides against Anopheles malaria vector populations of western Kenya 

  Silas Agumba, John E Gimnig, Lilian Ogonda, Maurice Ombok, Jackline Kosgei, Stephen Munga, Benard Guyah, Seline Omondi, Eric Ochomo (BioMed Central, 2019)

  Background: Malaria vector control is dependent on chemical insecticides applied to walls by indoor residual spraying or on long-lasting insecticidal nets. The emergence and spread of insecticide resistance in major malaria ...
• Factors Associated with Substance Abuse by Students in Medical Training Colleges in South Nyanza Region, Kenya 

  Daniel K. Kurui, James H. Ombaka, Lilian Ogonda (British Journal of Medical Health Research, 2020)

  Substance abuse is a worldwide public health challenge with college youth being among those affected. An estimated 10-15 % of students in medical training institutions risk substance abuse in their lifetime as they are ...
• Novel biomarkers with promising benefits for diagnosis of cervical neoplasia: a systematic review 

  Calleb George Onyango, Lilian Ogonda, Bernard Guyah, Clement Shiluli, Gregory Ganda, Omenge Elkanah Orang’o, Kirtika Patel (BioMed Central, 2020)

  Background: Cervical cancer screening is slowly transitioning from Pappanicolaou cytologic screening to primary Visual Inspection with Acetic Acid (VIA) or HPV testing as an effort to enhance early detection and ...
• Phenotypic and Genotypic Characteristics of Uropathogenic Escherichia coli Isolates from Kenya 

  Catherine Wawira Muriuki, Lilian Adhiambo Ogonda, Cecilia Kyanya, Daniel Matano, Clement Masakhwe, Erick Odoyo, Lillian Musila (Mary Ann Liebert, Inc., publishers, 2021)

  Introduction: Uropathogenic Escherichia coli (UPECs) are a significant cause of urinary tract infections (UTIs). In Kenya, UTIs are typically treated with b-lactam antibiotics without antibiotic susceptibility testing, ...
• Assessing quality of life among gynaecological cancer patients receiving care in the palliative care unit at Kenyatta national hospital 

  Isaac Ogoncho (University of Nairobi, 2014)

  Quality of life (QOL) assessment among cancer patients is considered to be an important aspect in palliative care. QOL assessment helps in the identification of the physical, psychological, social and spiritual needs of ...

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