Browsing Department of Medical Biochemistry by Issue Date
Now showing items 1-20 of 282
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Explaining the slowdown in medical spending growth among the elderly, 1999-2012.
(RTI International, 202-03-03)The American Heart Association, in conjunction with the National Institutes of Health, annually reports on the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core ... -
Hemoglobin Kenya, the product of a gamma-beta fusion gene: studies of the family.
(Elsevier, 1973-09)Recently, we reported the discovery of a new hemoglobin variant, Hb Kenya, in a 26-year-old Kenyan of the Nilotic Luo tribe [1]. Chemical characterization of the non-a chain of this hemoglobin showed that the amino ... -
The Kenya haemoglobin.
(East African medical journal, 1974)Haemoglobin Kenya is (at present) a rare haemoglobin variant, found so far only in the Luo tribe in Kenya. It came to light by its chance association with the Hb S trait, a situation giving rise to an unexpectedly high ... -
Severe hyponatraemia in hospital inpatients
(BMJ Publishing Group, 1978-12-09) -
The effect of α-thalassemia on the level of hybrid hemoglobin variants in heterozygotes
(Taylor & Francis, 1986-01-01)The influence of a relative deficiency in α chain production on the amount of Hemoglobins Kenya, P-Nilotic, and Lepore was determined. The level of these hybrid hemoglobins in heterozygotes was correlated to various states ... -
Changes in plasma HDL-cholesterol in women using oral contraceptives in Kenya
(University of Nairobi., 1987)125 black Kenyan women attending the Kenyatta National Family Welfare Clinic were randomly allocated to combined and fixed dose oral contraceptives (Eugynon: 500 mcg dl-norgestrel + 50 mcg ethinyl estradiol or Microgynon: ... -
A study of haemorrhoids as seen at the Kenyatta National Hospital with special reference to asymptomatic haemorrhoids.
(University of Nairobi, 1987)Haemorrhoids is a condition defined as a swelling at the anal margin, a pile. This condition has been known to afflict mankind for a long time having been documented from the time of Hipprocrates. So far it has not been ... -
Haplotypes and α globin gene analyses in sickle cell anaemia patients from Kenya
(Blackwell Publishing Ltd, 1987-02)Over 60 patients from the Luo and Luhya tribes of Western Kenya, aged 1–23 years. with severe sickle cell anaemia were evaluated through haematological and gene mapping analyses. Nearly all (56 of 58 tested) were homozygous ... -
Characterization of chromosomes with hybrid genes for Hb Lepore-Washington, Hb Lepore-Baltimore, Hb P-Nilotic, and Hb Kenya
(Springer-Verlag, 1987-09-01)This study concerns the characterization of chromosomes with hybrid genes for Hb Lepore-Washington (44 chromosomes), for Hb Lepore-Baltimore (5 chromosomes), for Hb P-Nilotic (8 chromosomes), and for Hb Kenya (7 chromosomes) ... -
Anaemia in elderly patients at Kenyatta National Hospital
(University of Nairobi, 1988)The main objective of this work was to study anaemia in elderly patients and hence contribute some baseline data for future possible work in this area. This prospective study covered 63 elderly patients of all types of ... -
beta S-haplotypes and alpha-thalassemia along the coastal belt of Kenya.
(East African medical journal, 1989)In this paper, we present data on studies of beta S-haplotypes and alpha-thalassemia gene in subjects from the indigenous population of the Coast Province of Kenya Of the 7SS patients studied, four were homozygous for beta ... -
Interaction of benzoquinones with mitochondria interferes with oxidative phosphorylation characteristics
(University of Nairobi, 1990)Studies with four benzoquinones, viz. juglone, embelin, maesaquinone and maesanin, on rat liver mitochondria oxidative phosphorylation have been carried out. Three of the benzoquinones are uncouplers in the order ... -
Interaction of benzoquinones with mitochondria interferes with oxidative phosphorylation characteristics
(No longer published by Elsevier, 1990-08-06)Studies with four benzoquinones, viz. juglone, embelin, maesaquinone and maesanin, on rat liver mitochondria oxidative phosphorylation have been carried out. Three of the benzoquinones are uncouplers in the order ... -
Experimental kwashiokor and obesity
(1991)Obesity and kwashiorkor syndrome were experimentally simulated in sprague dawley weaning rats to investigate the changes in energy metabolism and relative organ body weight ratios during over nutrition and under ... -
In vitro interstitial (Leydig) cell response to LH and concentrations of plasma testosterone and LH in the naked mole rat (Heterocephalus glaber, Ruppell)
(Blackwell Publishing Ltd, 1991-03-01)Summary Reproductive endocrinology of the male naked mole rat (Heterocephalus glaber) caught in the wild was studied. In vitro treatment of isolated Leydig cells using either normal dose of LH capable of stimulating ... -
Defects in resting metabolic rates and mitochondrial respiration in Kwashiorkor and dietary obese rats
(Springer-Verlag, 1991-07-01)Resting metabolic rates have been measured and compared with hepatic mitochondrial respiration in Kwashiorkor and diet-induced obese weaned rats. In Kwashiorkor, resting metabolic rate was 21% lower than the value of ... -
Maternal levels of alpha-fetoprotein in African women.
(East African medical journal, 1991-08)In a prospective and cross-sectional study, 147 serum samples from normal antenatal indigenous Kenyan women were analysed for alpha-fetoprotein (AFP) concentrations between 8 and 28 weeks gestation. There was progressive ... -
Changes in the concentrations of testosterone, luteinising hormone and progesterone associated with administration of embelin
(Elsevier, 1991-10-01)The mode of action of embelin, a naturally occurring plant benzoquinone with male fertility regulating potential, was investigated. Sexually mature white New Zealand male rabbits were injected intra-muscularly with ... -
External quality control performance in clinical chemistry: experience in Kenya.
(East African medical journal, 1993)Analysis of eleven biochemical laboratory tests was done during an International External Quality Assessment Scheme (IEQAS) in which the clinical chemistry laboratory at Kenyatta National Hospital participated. Technicon ...