School of Medicine
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Internal Medicine [57]
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Recent Submissions
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The Use of Photomicrographs and Real Specimens in Teaching Biology in Secondary Schools and its Effects on Students Performance, Kenya
(International Journal of Research Publication and Reviews, 2024)The study focused on examining the effect of teaching secondary school biology using photomicrographs and real specimens to enhance students’ academic performance in secondary schools in Kenya.it employed the constructivism ... -
The impact of sulfadoxine–pyrimethamine resistance on the effectiveness of intermittent preventive treatment for the prevention of malaria in pregnancy in Africa: an updated systematic review and meta-analysis
(Elsevier, 2025-07-14)Resistance of Plasmodium falciparum to sulfadoxine–pyrimethamine threatens the antimalarial effectiveness of intermittent preventive treatment during pregnancy (IPTp) with sulfadoxine–pyrimethamine (ITPp-SP) in sub-Saharan ... -
Incidence rates of malaria, meningitis, and mortality in children younger than 5 years: a prospective cohort study in Ghana and Kenya before the roll-out of the RTS,S/AS01E malaria vaccine from 2016 to 2022
(Elsevier, 2025-05-01)The RTS,S/AS01E malaria vaccine was introduced in selected communities of Ghana, Kenya, and Malawi in 2019 under a WHO-coordinated pilot programme. The scarcity of background disease incidence rates might hamper the ... -
Safety of RTS, S/AS01E malaria vaccine up to 1 year after the third dose in Ghana, Kenya, and Malawi (EPI-MAL-003): a phase 4 cohort event monitoring study
(Elsevier, 2025-06-01)RTS,S/AS01E has been successfully administered to over two million children since 2019 through the Malaria Vaccine Implementation Programme (MVIP). In this Article, we report the safety results of a study evaluating RTS,S/AS01E ... -
Plasmodium falciparum Parasitemia Does Not Diminish Neutralizing Antibody Responses After mRNA COVID-19 Booster Vaccination in HIV-infected Adults
(Oxford University Press, 2025-08-02)mRNA vaccines have emerged as powerful tools for the prevention of infectious diseases, but subclinical malaria may reduce vaccine immunogenicity. We evaluated neutralizing antibody responses in asymptomatic HIV-infected ... -
Hybrid versus vaccine immunity of mRNA-1273 among people living with HIV in East and Southern Africa: a prospective cohort analysis from the multicentre CoVPN 3008 (Ubuntu) study
(Elsevier, 2025-02-01)With limited access to mRNA COVID-19 vaccines in lower income countries, and people living with HIV (PLWH) largely excluded from clinical trials, Part A of the multicentre CoVPN 3008 (Ubuntu) study aimed to assess the ... -
Radiological study of the ossification process of medial clavicular epiphysis: The influence of sex and laterality
(Folia Morphologica, 2024-10-30)Radiological examination of bones such viz, clavicle have been developed to estimate the age of an individual without valid identification, or when suspected of providing inaccurate age. However, there is a paucity of ... -
Radiological study of the ossification process of medial clavicular epiphysis: The influence of sex and laterality
(Folia Morphologica, 2024-10-30)Radiological examination of bones such viz, clavicle have been developed to estimate the age of an individual without valid identification, or when suspected of providing inaccurate age. However, there is a paucity of ... -
Survival and Risk Factors for Late Preterm and Early Term Neonates Compared to Full-Term Infants at Garissa County Referral Hospital, Kenya
(AJOL, 2024-10-31)Preterm birth constitutes a significant health burden in Kenya, yet there is hardly any targeted research looking at the survival and specific risk factors associated with birth of late preterm neonates (LPNs) and early ... -
Organisation, staffing and resources of critical care units in Kenya
(Public Library of Science, 2023-07-27)To describe the organisation, staffing patterns and resources available in critical care units in Kenya. The secondary objective was to explore variations between units in the public and private sectors. -
Phase I study on the pharmacokinetics of intravaginal, self-administered artesunate vaginal pessaries among women in Kenya
(Cold Spring Harbor Laboratory Press, 2024-07-08)Cervical cancer remains a significant global health issue, especially in low- and middle-income countries (LMICs), where access to prevention and treatment is limited and women are at a higher risk of cervical cancer. ... -
Determination of reference intervals for common chemistry and immunoassay tests for Kenyan adults based on an internationally harmonized protocol and up-to-date statistical methods
(Public Library of Science, 2020-07-09)Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for 40 common chemistry and immunoassay tests as part of the IFCC global RI project. -
Histo-inhibitory effects of Warbugia ugandensis on high fat diet induced atherosclerosis in New Zealand rabbits
(Ajol, 2024-04-12)Atherosclerosis is a chronic inflammatory condition characterized by accumulation of plaque within a blood vessel. W. ugandensis has antioxidant and anti-inflammatory benefits therefore it might play an important role in ... -
Variation in origin and course of brachial artery among black African population: Cadaveric study in Western Kenya
(Ajol, 2024-04-12)Brachial artery (BA) is the main arterial supply to upper limb, it’sa direct continuation of axillary artery at the lower border of teres major and gives of profunda brachii which is the largest branch, superior ulnar ... -
Using Prostate-specific Antigen to Predict Gleason Scores in African Men Seeking Urological Services at a Referral Hospital in Kisumu, Kenya
(Journal of Advances in Medicine and Medical Research, 2024-07-23)Men are more likely to develop prostate lesions like benign prostatic hypertrophy and prostate cancer as they age. Prostate specific antigen (PSA), which is secreted in large quantities above normal levels of 0–4 ng/ml by ... -
Telemedicine in Africa: Applications, Opportunities, and Challenges
(IntechOpen, 2024-06-03)Telemedicine is the delivery of healthcare services remotely through information and communication technology (ICT) devices. Telemedicine offers a promising solution to address unmet healthcare needs across the African ... -
Effects of improved on-farm crop storage on DNA methylation of mothers and their infants: evidence from a randomized controlled trial in Kenya
(BioMed Central, 2024-07-08)Stress during pregnancy can lead to adverse maternal and infant health outcomes through epigenetic changes in the hypothalamic–pituitary–adrenal axis. Among farmers in low-income countries, one important stressor is food ... -
“There is nothing that can prevent me from supporting her:” men’s perspectives on their involvement and support of women’s use of topical therapy for cervical precancer treatment in Kenya
(Frontiers, 2024-03-12)Cervical cancer disproportionately impacts women in low- and middle-income countries (LMICs). The World Health Organization’s (WHO) 90/70/90 strategy aims to eliminate cervical cancer by 2030 by increasing HPV vaccination ... -
The Walter Reed Project, Kisumu Field Station: Impact of Research on Malaria Policy, Management, and Prevention.
(The American Journal of Tropical Medicine and Hygiene, 2024-04-23)The Walter Reed Project is a collaboration between the Walter Reed Army Institute of Research of the United States Department of Defense and the Kenya Medical Research Institute. The Kisumu field station, comprising four ... -
Evaluation of changes in coagulation factors in fresh frozen plasma during storage at-18° C for 5 weeks at Kisii Teaching and Referral Hospital
(Cold Spring Harbor Laboratory Press, 2023-04-12)Fresh frozen plasma is a critical substitute therapy in management of bleeding. Increased risk of venous thrombosis has been described to be associated with high plasma levels of several coagulation factors.