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Vitamin D status in healthy black African adults at a tertiary hospital in Nairobi, Kenya: a cross sectional study
(BioMed Central, 2018-12-01)
Vitamin D has been known since the twentieth Century for its benefits in bone health. Recent observational studies have demonstrated its benefits in infectious diseases such as tuberculosis and non-communicable diseases ...
Metabolic syndrome and its predictors in an urban population in Kenya: a cross sectional study
(BioMed Central, 2017-12-01)
The metabolic syndrome (MetS) is a clustering of interrelated risk factors which doubles the risk of cardio-vascular disease (CVD) in 5–10 years and increases the risk of type 2 diabetes 5 fold. The identification of ...
Comparison of equations for estimating glomerular filtration rate in screening for chronic kidney disease in asymptomatic black Africans: a cross sectional study
(BioMed Central, 2017-12)
Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of ...
HIV-1 progression links with viral genetic variability and subtype, and patient’s HLA type: analysis of a Nairobi-Kenyan cohort
(Springer Berlin Heidelberg, 2014-02-01)
In a Nairobi-Kenyan cohort of 50 HIV-1 positive patients, we analysed the prevalence of HIV-1 subtypes and human leucocyte antigen (HLA) alleles. From this cohort, 33 patients were selected for the analysis of HIV-1 infection ...
Prevalence of transmitted drug resistance mutations in HIV-1-infected drug-naive patients from urban and suburban regions of Kenya
(Mary Ann Liebert, Inc., 2016-03-01)
HIV was first described in Kenya in 1984–1985. Currently, Kenya has an estimated HIV-1 prevalence of 6.2%. With the introduction of antiretroviral drugs, the survival of most HIV patients has been prolonged markedly. ...
Measurement of improvement achieved by participation in international laboratory accreditation in sub-Saharan Africa: the Aga Khan University Hospital Nairobi experience
(Oxford University Press, 2014-02-02)
As part of the ISO 15189:2007 accreditation process, the Aga Khan University Hospital Nairobi laboratory became the first internationally accredited hospital laboratory in sub-Saharan Africa outside South Africa in 2011 ...
Complete blood count reference intervals from a healthy adult urban population in Kenya
(Public Library of Science, 2018-06-07)
There are racial, ethnic and geographical differences in complete blood count (CBC) blood count (CBC) and therefore it is necessary to establish RIs that are population specific. Several studies have been carried out in ...
Population-specific evolution of HIV Gag epitopes in genetically diverged patients
(Elsevier, 2013-06-01)
Under the host selection pressure HIV evolves rapidly to override crucial steps in the antigen presentation pathway. This allows the virus to escape binding and recognition by cytotoxic T lymphocytes. Selection pressures ...
Macro CK in patients with elevated troponin I levels: case report: online article
(Clinics Cardive Publishing, 2012-02-01)
CK-MB activity levels can be falsely elevated by the presence of macro CK, especially if immuno-inhibition assays are used in the measurement. In patients with macro CK and cardiac pathology that could result in an elevated ...
Family history as a risk for early-onset type 2 diabetes in Kenyan patients.
(EBSCO Industries, Inc, 2014)
Early-onset type 2 diabetes is regarded as disease occurring before the age of 40 years. It is well described, and increasing in prevalence, but there is little information from Africa. We therefore assessed the prevalence ...