Browsing Department of Medical Biochemistry by Title
Now showing items 193-212 of 282
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Paediatric rhabdomyosarcoma: MyoD1 demonstration in routinely processed tissue sections using wet heat pretreatment (pressure cooking) for antigen retrieval.
(Journal of clinical pathology, 1997-01-01)AIMS: To investigate wet heat pretreatment (pressure cooking) as a means of antigen retrieval for demonstration of MyoD1 in paraffin wax embedded tissue. METHODS: Routinely processed tissue sections of transmission electron ... -
Pathological sub-types, risk factors and outcome of stroke at the Nairobi Hospital, Kenya
(East African medical journal, 2008)Background: Stroke is one of the most common causes of morbidity and mortality the world over. Established risk factors such as arterial hypertension, diabetes mellitus, cigarette smoking, hyper-lipidaemia, micro-vascular ... -
Patient Willingness To Undergraduate Medical Student Involvement In Their Care At The Kenyatta National Hospital: A Cross Sectional Study.
(University of Nairobi, 2010)Research Question: How willing are patients to the participation of medical students in their care. Objective: To determine the level of patient willingness to medical student participation in their care Design: Cross ... -
Perception of Academic Staff in Kenyan Public Universities towards Application of Performance Appraisal Results in Training and Promotion decisions
(2011-11)PERCEPTION OF ACADEMIC STAFF IN KENYAN PUBLIC UNIVERSITIES TOWARDS APPLICATION OF PERFORMANCE APPRAISAL RESULTS IN TRAINING AND PROMOTION DECISIONS DOMINIC WERE MAKAWITI A Management Research Project Submitted in ... -
Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study
(Elsevier, 2018-04-21)There is a need to increase access to surgical treatments in African countries, but perioperative complications represent a major global health-care burden. There are few studies describing surgical outcomes in ... -
Persistence of oncogenic and non-oncogenic human papillomavirus is associated with human immunodeficiency virus infection in Kenyan women
(Sage, 2020)Objectives: Cervical cancer is caused by persistent infection with oncogenic, or “high-risk” types of human papillomaviruses, and is the most common malignancy in Kenyan women. A longitudinal study was initiated to ... -
Perspectives of Women on Strategies to Improve the Number of Male Partners Testing for HIV at the Antenatal Clinic in Western Kenya, 2015.
(International Journal of Scientific and Research Publications,, 2015)- Mother to child transmission of HIV (MTCT) remains a significant public health problem in Western Kenya. Male partner testing at the antenatal clinic (ANC) has been cited as a key strategy to reduce MTCT. The Western ... -
The pesticide heptachlor affects steroid hormone secretion in isolated follicular and luteal cells of rat
(Elsevier, 2006-09-01)Heptachlor, a chlorinated hydrocarbon pesticide, suppresses the production of progesterone and estradiol in the female rat in vivo or in isolated ovaries in vitro. In this study the effect of heptachlor on steroid ... -
Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study
(spring link, 2014)Background Alternatives to treatment for malaria treatment of travellers are needed in the USA and in Europe for travellers who return with severe malaria infections. The objective of this study is to show the pharmacokinetic ... -
Phenotypic and Genotypic Characteristics of Uropathogenic Escherichia coli Isolates from Kenya
(Mary Ann Liebert, Inc., publishers, 2021)Introduction: Uropathogenic Escherichia coli (UPECs) are a significant cause of urinary tract infections (UTIs). In Kenya, UTIs are typically treated with b-lactam antibiotics without antibiotic susceptibility testing, ... -
Pitting of malaria parasites and spherocyte formation
(Pub Med Central, 2006-07-31)BACKGROUND: A high prevalence of spherocytes was detected in blood smears of children enrolled in a case control study conducted in the malaria holoendemic Lake Victoria basin. It was speculated that the spherocytes ... -
Point mutation (C446S) in the thyroid hormone receptor β gene in a black South African kindred with thyroid hormone resistance syndrome
(1999)Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS/Unless otherwise stated above, the content of this bibliographic record may ... -
Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria
(Pub Med Central, 2011-08)BACKGROUND: Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young ... -
Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating Gamma Interferon Levels
(American Society for Microbiology, 2012)An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) ... -
Population-specific evolution of HIV Gag epitopes in genetically diverged patients
(Elsevier, 2013-06-01)Under the host selection pressure HIV evolves rapidly to override crucial steps in the antigen presentation pathway. This allows the virus to escape binding and recognition by cytotoxic T lymphocytes. Selection pressures ... -
Post Oesophagectomy Leakage at Kenyatta National Hospital–Nairobi-Kenya
(East and Central African Journal of Surgery, 2005)Background: Post oesophagectomy leakage is a common postoperative complication. This present review was aimed at documenting the problem of post-oesophagectomy leakage and associated variables at Kenyatta National Hospital ... -
Post-infarction ventricular septal defect in Nairobi: Case report
(Kenya Medical Association, 2015-12)Post infarction ventricular septal defect results from perforation of the ventricular septum secondary to ischaemic injury following myocardial infarction. Ischaemic heart disease till recently was thought to be an uncommon ... -
The Potential of Differentiation-Related Gene-1 (DRG1) as a Biomarker for Metastasis of Estrogen Receptor-Positive Breast Cancer
(Journal of Advances in Medicine and Medical Research(JAMMR), 2021)Breast cancer is major burden worldwide and the majority of breast cancers express estrogen receptors (ER) suggesting a high dependence on estrogen hormone. Age is among the major determinants of breast cancer development, ... -
Pregnancy in open heart surgical patients at Kenyatta National Hospital.
(East African medical journal, 1999-01-01)In the past, the Kenyatta National Hospital heart unit policy has been to discourage pregnancy among patients following open heart surgery for valve replacement, in view of the adverse effects of warfarin. OBJECTIVE: To ... -
Prevalence and Factors Associated with Depression among Patients with Epilepsy at Aga Khan University Teaching Hospital Nairobi
(2015-10-01)Objective: To determine the prevalence and factors associated with depression in patients with epilepsy at Aga Khan University Hospital; Nairobi. Design: A Cross-Sectional Survey. Setting: Neurology clinic, Aga Khan ...