Browsing Department of Medical Biochemistry by Title
Now showing items 213-232 of 282
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Prevalence and incidence of congenital anomalies amongst babies born to women with sickle cell disease and exposed to hydroxyurea during pregnancy: a systematic review protocol
(2018)What is the prevalence and incidence of congenital anomalies among babies born to women with sickle cell disease (SCD) and who have been exposed to hydroxyurea (HU) therapy at any time in their pregnancy? The objective ... -
Prevalence of metabolic syndrome components among University students in Kenya
(East African Medical Journal, 2018)Objective: To examine the prevalence and major components of MS among Maseno University students. Design: Descriptive cross- sectional study design Setting: Maseno University, Medical Physiology laboratory Participants: ... -
Prevalence of transmitted drug resistance mutations in HIV-1-infected drug-naive patients from urban and suburban regions of Kenya
(Mary Ann Liebert, Inc., 2016-03-01)HIV was first described in Kenya in 1984–1985. Currently, Kenya has an estimated HIV-1 prevalence of 6.2%. With the introduction of antiretroviral drugs, the survival of most HIV patients has been prolonged markedly. ... -
Prevalence, Associated Risk Factors and Progression Of Asymptomatic Peripheral Arterial Disease At Kenyatta National Hospital
(University of Nairobi, 2016)The prevalence of peripheral arterial disease worldwide has been estimated at between 4.5% and 29%. Peripheral arterial disease can be asymptomatic or symptomatic. It is an independent risk factor for cardiovascular morbidity ... -
Prevalence, Progression and Associated Risk Factors of Asymptomatic Peripheral Arterial Disease
(The Surgical Society of Kenya, 2017)Introduction: The prevalence of peripheral arterial disease (PAD) ranges between 4.5% and 57% and is independently associated with cardiovascular disease burden irrespective of symptoms. Two thirds of cases are thought to ... -
Primary cerebral angitis of the central nervous
(East African medical journal, 2008)We report a case of a 28 year old female who presented with variedly progressive stroke like illness and raised intracranial pressure. Brain MRI scans revealed pericallosal and periventricular hyperintensities with oedema. ... -
Progesterone, estradiol and their respective receptors in leiomyoma and adjacent normal myometria of black Kenyan women
(University of Nairobi, 2018) -
Prolactin levels in South African women on injectable progestogen contraceptives
(Health and Medical Publishing Group, 1999)To demonstrate the effect of depot medroxyprogesterone acetate (DMPA) and norethisterone oenanthate (NET EN) on basal prolactin levels with a view to investigating the role of progestogen-induced hyperprolactinaemia ... -
Proteins Associated with SF3a60 in T. brucei
(Public Library of Science, 2014-03-20)Trypanosoma brucei relies on Spliced leader trans splicing to generate functional messenger RNAs. Trans splicing joins the specialized SL exon from the SL RNA to pre-mRNAs and is mediated by the trans-spliceosome, which ... -
Protein–protein interaction map of the Trypanosoma cruzi ribosomal P protein complex
(Elsevier, 2005-09-12)The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. Four out of five ribosomal P proteins of Trypanosoma cruzi, TcP0, TcP1α, TcP2α, and TcP2β had been ... -
Quality Blood Sampling Techniques and Influence of Socio cultural Factors among ARVs Forces Community in Seeking Healthcare
(SMU Medical Journal, 2016-01)Project monitoring and evaluation (M/E) determines resource accountability and its impact to various stakeholders. Plenary project success requires holistic community participation and empowerment. However, this approach ... -
Quality of life among gynaecological cancer patients receiving palliative care in Kenya: A cross-sectional study
(MA Healthcare, 2016-01-02)Background/Aims: Cancer and its treatment affects the quality of life in patients. In Africa, there is limited research available on the quality of life among cancer patients. This study describes quality of life in ... -
Quality of post abortion care services in Bungoma District hospital, Kenya
(University of Nairobi,, 2010)Abortion is the commonest complication of early pregnancy occurring in 10% - 15% of pregnancies. The demand for Post Abortion Care remains high in hospitals in Kenya. The public health rationale to address abortions and ... -
Rachs-1 system in rist stratification for congenital heart disease surgery outcome
(East African medical journal, 2008-05-28)Background: The Risk Adjustment in Congenital Heart Surgery (RACHS-1) system has been used as a benchmark to compare surgical results in developed countries. Its ability to stratify postoperative mortality risk has been ... -
Red blood cell immune complex binding capacity in children with sickle cell trait (HbAS) living in P. falciparum malaria holoendemic region of Western Kenya
(ARMY MEDICAL RESEARCH UNIT-KENYA APO NEW YORK 09675, 2013)Malaria infection leads to the formation of circulating immune complexes CICs which have been implicated in the pathogenesis of complicated malaria which includes severe malarial anemia. Children with sickle cell trait ... -
Reduced immune complex binding capacity and increased complement susceptibility of red cells from children with severe malaria-associated anemia
(The Feinstein Institute for Medical Research, 2008-03)Plasmodium falciparum malaria causes 1–2 million deaths per year. Most deaths occur as a result of complications such as severe anemia and cerebral malaria (CM)(coma). Red cells of children with severe malaria-associated ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality
(Pub Med Central, 2012-08)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (− 173) and IFNA8 (− 884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all
(Springer-Verlag, 2012-08-01)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (− 173) and IFNA8 (− 884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all …
(Springer-Verlag, 2012)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
Reduced Systemic Bicyclo-Prostaglandin-E2 and Cyclooxygenase-2 Gene Expression are Associated with Inefficient Erythropoiesis and Enhanced Uptake of Monocytic Hemozoin in Children with Severe Malarial Anemia
(Pub Med Central, 2012-08)In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children <48 mos. and manifests as severe malarial anemia [SMA; hemoglobin (Hb)<6.0 g/dL]. Induction of high levels of prostaglandin-E2 ...