Browsing Department of Medical Biochemistry by Title
Now showing items 223-242 of 282
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Quality Blood Sampling Techniques and Influence of Socio cultural Factors among ARVs Forces Community in Seeking Healthcare
(SMU Medical Journal, 2016-01)Project monitoring and evaluation (M/E) determines resource accountability and its impact to various stakeholders. Plenary project success requires holistic community participation and empowerment. However, this approach ... -
Quality of life among gynaecological cancer patients receiving palliative care in Kenya: A cross-sectional study
(MA Healthcare, 2016-01-02)Background/Aims: Cancer and its treatment affects the quality of life in patients. In Africa, there is limited research available on the quality of life among cancer patients. This study describes quality of life in ... -
Quality of post abortion care services in Bungoma District hospital, Kenya
(University of Nairobi,, 2010)Abortion is the commonest complication of early pregnancy occurring in 10% - 15% of pregnancies. The demand for Post Abortion Care remains high in hospitals in Kenya. The public health rationale to address abortions and ... -
Rachs-1 system in rist stratification for congenital heart disease surgery outcome
(East African medical journal, 2008-05-28)Background: The Risk Adjustment in Congenital Heart Surgery (RACHS-1) system has been used as a benchmark to compare surgical results in developed countries. Its ability to stratify postoperative mortality risk has been ... -
Red blood cell immune complex binding capacity in children with sickle cell trait (HbAS) living in P. falciparum malaria holoendemic region of Western Kenya
(ARMY MEDICAL RESEARCH UNIT-KENYA APO NEW YORK 09675, 2013)Malaria infection leads to the formation of circulating immune complexes CICs which have been implicated in the pathogenesis of complicated malaria which includes severe malarial anemia. Children with sickle cell trait ... -
Reduced immune complex binding capacity and increased complement susceptibility of red cells from children with severe malaria-associated anemia
(The Feinstein Institute for Medical Research, 2008-03)Plasmodium falciparum malaria causes 1–2 million deaths per year. Most deaths occur as a result of complications such as severe anemia and cerebral malaria (CM)(coma). Red cells of children with severe malaria-associated ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality
(Pub Med Central, 2012-08)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (− 173) and IFNA8 (− 884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all
(Springer-Verlag, 2012-08-01)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
Reduced interferon (IFN)-α conditioned by IFNA2 (− 173) and IFNA8 (− 884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all …
(Springer-Verlag, 2012)Severe malarial anemia (SMA) is a leading cause of pediatric morbidity and mortality in holoendemic Plasmodium falciparum transmission areas. Although dysregulation in cytokine production is an important etiology of SMA, ... -
Reduced Systemic Bicyclo-Prostaglandin-E2 and Cyclooxygenase-2 Gene Expression are Associated with Inefficient Erythropoiesis and Enhanced Uptake of Monocytic Hemozoin in Children with Severe Malarial Anemia
(Pub Med Central, 2012-08)In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children <48 mos. and manifests as severe malarial anemia [SMA; hemoglobin (Hb)<6.0 g/dL]. Induction of high levels of prostaglandin-E2 ... -
Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia
(Wiley Subscription Services, Inc., A Wiley Company, 2012)In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children aged <48 months and manifests as severe malarial anemia [SMA; hemoglobin (Hb) < 6.0 g/dL]. Induction of high levels of ... -
Reference intervals for some biochemical parameters in the aged Kenyan population.
(East African Medical Journal,, 1994)Serum levels for sodium, potassium, calcium, inorganic phosphate, urea nitrogen and creatinine were determined in 1101 male and 181 female patients aged 50 years and above. The determinations were carried out on the SMA ... -
Reflections on the first pan‐african conference on biochemistry and molecular biology
(Headington Hill Hall, 1997-07-01)After a couple of years of consultations with leading biochemists/molecular biologists in Africa and from abroad (playing advisory roles), the First Pan-African Conference on Biochemistry and Molecular Biology was ... -
Reproductive toxicology: Edited by Raphael J Witorsch. pp 335. Raven Press, New York. 1995 ISBN 0‐7818‐0225‐9
(Headington Hill Hall, 1995-07-01)This volume incorporates material on stilbenes, bibenzyls, phenanthrene, their 9, 10- derivatives, and related plant products (similar in biosynthesis to fiavonoids), all derived from cinnamic acid and malonyl-CoA. The ... -
Research capacity. Enabling the genomic revolution in Africa.
(Science (New York, NY), 2014-06-01)Our understanding of genome biology, genomics, and disease, and even human history, has advanced tremendously with the completion of the Human Genome Project. Technological advances coupled with significant cost reductions ... -
A review of electroencephlagrams done at the Kenyatta National Hospital, Nairobi
(East African Medical Journal, 2008-06-11)Background: Electroencephalogram based studies done elsewhere suggest that epileptiform activity originates predominantly from the left cortical hemisphere. There is evidence that partial epilepsies (focal spike and wave ... -
Rheumatic fever and rheumatic heart disease: where are we now in South Africa?: ASAP programme
(The South African Heart Association, 2009)South Africa continues to face unacceptably high rates of rheumatic fever (RF) and rheumatic heart disease (RHD), despite readily available and inexpensive preventive measures. However, in the past several years, key players ... -
Risk of conjunctival contamination from blood splashes during surgery at the Kenyatta National Hospital, Nairobi
(East African medical journal, 2008-12-15)Objectives: To determine the utilisation rate of design specific eye protection by surgeons and to assess the risk of conjunctival contamination with blood splashes during surgery. Design: Cross sectional, observational ... -
The role of echocardiography in diagnosing carditis in the setting of acute rheumatic fever
(Cambridge University Press, 2009-08)Sir, Vijayalakshmi and her colleagues are to be commended for their paper.1 We disagree, however, with the use of a scoring system to make an echocardiographic diagnosis of carditis due to acute rheumatic fever. We ... -
The Role of Mobile Health in Supporting Cancer Prevention, Detection, Treatment and Palliative Care in Low and Middle Income Countries: A Scoping Review
(Scientific & Academic Publishing, 2017)Cancer is one of the non-communicable diseases with high morbidity and mortality rates, particularly in low-and-middle income countries. Increasing cancer burden is attributable to lifestyle risk factors, poor health ...