Browsing Department of Medical Biochemistry by Title
Now showing items 206-225 of 282
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Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating Gamma Interferon Levels
(American Society for Microbiology, 2012)An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) ... -
Population-specific evolution of HIV Gag epitopes in genetically diverged patients
(Elsevier, 2013-06-01)Under the host selection pressure HIV evolves rapidly to override crucial steps in the antigen presentation pathway. This allows the virus to escape binding and recognition by cytotoxic T lymphocytes. Selection pressures ... -
Post Oesophagectomy Leakage at Kenyatta National Hospital–Nairobi-Kenya
(East and Central African Journal of Surgery, 2005)Background: Post oesophagectomy leakage is a common postoperative complication. This present review was aimed at documenting the problem of post-oesophagectomy leakage and associated variables at Kenyatta National Hospital ... -
Post-infarction ventricular septal defect in Nairobi: Case report
(Kenya Medical Association, 2015-12)Post infarction ventricular septal defect results from perforation of the ventricular septum secondary to ischaemic injury following myocardial infarction. Ischaemic heart disease till recently was thought to be an uncommon ... -
The Potential of Differentiation-Related Gene-1 (DRG1) as a Biomarker for Metastasis of Estrogen Receptor-Positive Breast Cancer
(Journal of Advances in Medicine and Medical Research(JAMMR), 2021)Breast cancer is major burden worldwide and the majority of breast cancers express estrogen receptors (ER) suggesting a high dependence on estrogen hormone. Age is among the major determinants of breast cancer development, ... -
Pregnancy in open heart surgical patients at Kenyatta National Hospital.
(East African medical journal, 1999-01-01)In the past, the Kenyatta National Hospital heart unit policy has been to discourage pregnancy among patients following open heart surgery for valve replacement, in view of the adverse effects of warfarin. OBJECTIVE: To ... -
Prevalence and Factors Associated with Depression among Patients with Epilepsy at Aga Khan University Teaching Hospital Nairobi
(2015-10-01)Objective: To determine the prevalence and factors associated with depression in patients with epilepsy at Aga Khan University Hospital; Nairobi. Design: A Cross-Sectional Survey. Setting: Neurology clinic, Aga Khan ... -
Prevalence and incidence of congenital anomalies amongst babies born to women with sickle cell disease and exposed to hydroxyurea during pregnancy: a systematic review protocol
(2018)What is the prevalence and incidence of congenital anomalies among babies born to women with sickle cell disease (SCD) and who have been exposed to hydroxyurea (HU) therapy at any time in their pregnancy? The objective ... -
Prevalence of metabolic syndrome components among University students in Kenya
(East African Medical Journal, 2018)Objective: To examine the prevalence and major components of MS among Maseno University students. Design: Descriptive cross- sectional study design Setting: Maseno University, Medical Physiology laboratory Participants: ... -
Prevalence of transmitted drug resistance mutations in HIV-1-infected drug-naive patients from urban and suburban regions of Kenya
(Mary Ann Liebert, Inc., 2016-03-01)HIV was first described in Kenya in 1984–1985. Currently, Kenya has an estimated HIV-1 prevalence of 6.2%. With the introduction of antiretroviral drugs, the survival of most HIV patients has been prolonged markedly. ... -
Prevalence, Associated Risk Factors and Progression Of Asymptomatic Peripheral Arterial Disease At Kenyatta National Hospital
(University of Nairobi, 2016)The prevalence of peripheral arterial disease worldwide has been estimated at between 4.5% and 29%. Peripheral arterial disease can be asymptomatic or symptomatic. It is an independent risk factor for cardiovascular morbidity ... -
Prevalence, Progression and Associated Risk Factors of Asymptomatic Peripheral Arterial Disease
(The Surgical Society of Kenya, 2017)Introduction: The prevalence of peripheral arterial disease (PAD) ranges between 4.5% and 57% and is independently associated with cardiovascular disease burden irrespective of symptoms. Two thirds of cases are thought to ... -
Primary cerebral angitis of the central nervous
(East African medical journal, 2008)We report a case of a 28 year old female who presented with variedly progressive stroke like illness and raised intracranial pressure. Brain MRI scans revealed pericallosal and periventricular hyperintensities with oedema. ... -
Progesterone, estradiol and their respective receptors in leiomyoma and adjacent normal myometria of black Kenyan women
(University of Nairobi, 2018) -
Prolactin levels in South African women on injectable progestogen contraceptives
(Health and Medical Publishing Group, 1999)To demonstrate the effect of depot medroxyprogesterone acetate (DMPA) and norethisterone oenanthate (NET EN) on basal prolactin levels with a view to investigating the role of progestogen-induced hyperprolactinaemia ... -
Proteins Associated with SF3a60 in T. brucei
(Public Library of Science, 2014-03-20)Trypanosoma brucei relies on Spliced leader trans splicing to generate functional messenger RNAs. Trans splicing joins the specialized SL exon from the SL RNA to pre-mRNAs and is mediated by the trans-spliceosome, which ... -
Protein–protein interaction map of the Trypanosoma cruzi ribosomal P protein complex
(Elsevier, 2005-09-12)The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. Four out of five ribosomal P proteins of Trypanosoma cruzi, TcP0, TcP1α, TcP2α, and TcP2β had been ... -
Quality Blood Sampling Techniques and Influence of Socio cultural Factors among ARVs Forces Community in Seeking Healthcare
(SMU Medical Journal, 2016-01)Project monitoring and evaluation (M/E) determines resource accountability and its impact to various stakeholders. Plenary project success requires holistic community participation and empowerment. However, this approach ... -
Quality of life among gynaecological cancer patients receiving palliative care in Kenya: A cross-sectional study
(MA Healthcare, 2016-01-02)Background/Aims: Cancer and its treatment affects the quality of life in patients. In Africa, there is limited research available on the quality of life among cancer patients. This study describes quality of life in ... -
Quality of post abortion care services in Bungoma District hospital, Kenya
(University of Nairobi,, 2010)Abortion is the commonest complication of early pregnancy occurring in 10% - 15% of pregnancies. The demand for Post Abortion Care remains high in hospitals in Kenya. The public health rationale to address abortions and ...