Browsing Department of Medical Biochemistry by Title
Now showing items 97-116 of 282
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Factors associated with non-adherence to Artemisinin-based combination therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya.
(Pub Med Central, 2012-06)Background Over the years, reports implicate improper anti-malarial use as a major contributor of morbidity and mortality amongst millions of residents in malaria endemic areas, Kenya included. However, there are limited ... -
Factors Associated with Substance Abuse by Students in Medical Training Colleges in South Nyanza Region, Kenya
(British Journal of Medical Health Research, 2020)Substance abuse is a worldwide public health challenge with college youth being among those affected. An estimated 10-15 % of students in medical training institutions risk substance abuse in their lifetime as they are ... -
Factors underlying stigmatization of epilepsy: A comparative case study of Suba and Meru Central Districts, Kenya
(American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS), 2014)Epilepsy is the most common neurological disorder known to mankind. It is shrouded in mystery and associated with supernatural forces resulting in social stigma, systematic discrimination and psychological morbidity to the ... -
Family history as a risk for early-onset type 2 diabetes in Kenyan patients.
(EBSCO Industries, Inc, 2014)Early-onset type 2 diabetes is regarded as disease occurring before the age of 40 years. It is well described, and increasing in prevalence, but there is little information from Africa. We therefore assessed the prevalence ... -
Fibrosarcoma of the lung with extrapulmonary manifestations
(East African Medical Journal,, 1995-07-01)A 50-year-old female presented with a five months history of recurrent attacks of dizziness, sweatiness, tremors and fainting with loss of consciousness. These were found to be due to hypoglycaemic episodes with blood ... -
Follow up of patients after open heart surgery.
(East African medical journal, 1998-12)To determine the patient drop out to postoperative follow up for heart patients at the Kenyatta National Hospital. DESIGN SETTING AND PARTICIPANTS: The study analysed the postoperative attendance of heart patients to the ... -
Follow up pattern for post oesophagectomy patients at a single centre: association with peri-operative variables
(Annals of African Surgery, 2007)BACKGROUND: Though the operative mortality for resection of oesophageal malignancy has fallen significantly over time, the overall postoperative survival has remained fairly constant irrespective of surgical techniques, ... -
Functional characterization and protein–protein interactions of trypanosome splicing factors U2AF35, U2AF65 and SF1
(Elsevier, 2009-04-01)Early in the assembly of the spliceosome of eukaryotes the branch-point binding protein (BBP, also called SF1) recognizes the branch point sequence, whereas the heterodimer U2AF consisting of a 65 and a 35 kDa subunit, ... -
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.
(Pub Med Central, 2012-02)Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variation in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ... -
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality
(Pub Med Central, 2011-12)Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where Plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ... -
Fusion of the Medial Clavicular Epiphysis in the South African and Kenyan Populations.
(International Journal of Morphology, 2019): Age estimation from clavicular ossification has been studied by many researchers based on the pattern and degree of the epiphyseal union through the use of dry bone specimens, radiographs, CT and MRI. These studies found ... -
Fusión de la Epífisis Clavicular Medial en las Poblaciones de Sudáfrica y Kenia
(Sociedad Chilena de Anatomía, 2019)Age estimation from clavicular ossification has been studied by many researchers based on the pattern and degree of the epiphyseal union through the use of dry bone specimens, radiographs, CT and MRI. These studies found ... -
GalAactosaemia in black South African children
(Kenya Medical Association, 1999)To evaluate the clinical and biochemical features of all black children confirmed to have galactosaemia from the KwaZulu Natal Province of South Africa. -
Genetic analysis of HIV-1 subtypes in Nairobi, Kenya
(Public Library of Science, 2008-09-11)Genetic analysis of a viral infection helps in following its spread in a given population, in tracking the routes of infection and, where applicable, in vaccine design. Additionally, sequence analysis of the viral genome ... -
Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine
(Massachusetts Medical Society, 2015)BACKGROUND The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium falciparum and has partial protective efficacy against clinical and severe malaria disease in infants and children. We investigated ... -
Genetic diversity and relationships among populations of jackfruit, an underutilized nutrient-rich climate-smart fruit tree crop in Kenya and Uganda
(Taylor & Francis, 2022-09-03)Jackfruit (Artocarpus heterophyllus Lam.) is an underutilized fruit tree crop in East Africa. Despite its importance for food and nutritional security, only limited information exists on the extent of genetic variability ... -
The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis
(Springer, New York, NY, 2013)Plasmodium falciparum malaria is a leading global cause of morbidity and mortality of infectious disease origin. Here, we focus largely on P. falciparum malaria in sub-Saharan Africa since this geographic region bears the ... -
The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis
(Springer, 2012)Plasmodium falciparum malaria is a leading global cause of morbidity and mortality of infectious disease origin. Here, we focus largely on P. falciparum malaria in sub-Saharan Africa since this geographic region bears the ... -
A global" School for Surgeons" could help bridge the Healthcare Human Resource Crisis in Sub-Saharan Africa
(University of Nairobi, 2009)Appropriately designed elearning programmes (including Best or School for Surgeons) may allow more efficient use of consultant teaching time. Using funding from Irish Aid, we piloted these existing e-learning tools in a ... -
Haemostatic disorders in patients with breast cancer at Kenyatta national hospital, Kenya
(University of Nairobi, 2010)Haemostatic disorders (thrombosis and haemorrhage) are increasingly being investigated and assessed as factors that influence outcome of treatment of solid tumors including breast cancer. There is little data available on ...