Department of Medical Biochemistry: Recent submissions

Now showing items 201-220 of 282

    • Follow up pattern for post oesophagectomy patients at a single centre: association with peri-operative variables 

      SW Ogendo (Annals of African Surgery, 2007)
      BACKGROUND: Though the operative mortality for resection of oesophageal malignancy has fallen significantly over time, the overall postoperative survival has remained fairly constant irrespective of surgical techniques, ...

    • Management pathway for congenital heart disease at Kenyatta National Hospital, Nairobi 

      MN Awori, SW Ogendo, SW Gitome, SK Ong'uti, NG Obonyo (East African medical journal, 2007)
      „Background: Congenital heart disease (CHD) is a significant cause of death amongst infants. The timing of treatment in relation to the natural history of the disease correlates with the treatment outcome. Objectives: To ...

    • Weight change post oesophagectomy for carcinoma of oesophagus 

      SW Ogendo (East African medical journal, 2007)
      Objective: To determine the pattern of weight changes observed in postoperative oesophagectomy patients at the Kenyatta National Hospital and evaluate weight change with selected preoperative variables. Design: A prospective ...

    • Of lice and men: A case of Bartonella quintana 

      Liesl Zuehlke, Rik De Decker, John Hewitson, Neil Seller, Andrew Whitelaw, John Lawrenson (SA MEDICAL ASSOC, 2007-11-01)
      Of lice and men: A case of Bartonella quintana

    • No evidence for an association between the mitochondrial variant T16189C and dilated cardiomyopathy: A systematic review and meta-analysis 

      ME Engel, G Shaboodien, BM Mayosi (SA MEDICAL ASSOC, 2007-11-01)
      No evidence for an association between the mitochondrial variant T16189C and dilated cardiomyopathy: A systematic review and meta-analysis

    • Ortner syndrome 

      E Meyer, NE Jones, LJ Zühlke (South African Journal of Child Health, 2008)
      Ortner syndrome, or cardio-vocal syndrome, is a clinical entity characterised by hoarseness (secondary to left-sided recurrent laryngeal nerve palsy) caused by cardiovascular disease. It has been reported in up to 12% of ...

    • Rachs-1 system in rist stratification for congenital heart disease surgery outcome 

      MN Awori, SW Ogendo (East African medical journal, 2008-05-28)
      Background: The Risk Adjustment in Congenital Heart Surgery (RACHS-1) system has been used as a benchmark to compare surgical results in developed countries. Its ability to stratify postoperative mortality risk has been ...

    • Risk of conjunctival contamination from blood splashes during surgery at the Kenyatta National Hospital, Nairobi 

      East African medical journal (East African medical journal, 2008-12-15)
      Objectives: To determine the utilisation rate of design specific eye protection by surgeons and to assess the risk of conjunctival contamination with blood splashes during surgery. Design: Cross sectional, observational ...

    • Rheumatic fever and rheumatic heart disease: where are we now in South Africa?: ASAP programme 

      Mark E Engel, Liesl Zuhlke, Kate Robertson (The South African Heart Association, 2009)
      South Africa continues to face unacceptably high rates of rheumatic fever (RF) and rheumatic heart disease (RHD), despite readily available and inexpensive preventive measures. However, in the past several years, key players ...

    • A global" School for Surgeons" could help bridge the Healthcare Human Resource Crisis in Sub-Saharan Africa 

      STEPHEN OGENDO, SWO Ogendo (University of Nairobi, 2009)
      Appropriately designed elearning programmes (including Best or School for Surgeons) may allow more efficient use of consultant teaching time. Using funding from Irish Aid, we piloted these existing e-learning tools in a ...

    • The role of echocardiography in diagnosing carditis in the setting of acute rheumatic fever 

      John Lawrenson, Liesl Zühlke, Rik De Decker (Cambridge University Press, 2009-08)
      Sir, Vijayalakshmi and her colleagues are to be commended for their paper.1 We disagree, however, with the use of a scoring system to make an echocardiographic diagnosis of carditis due to acute rheumatic fever. We ...

    • The mitochondrial DNA T16189C polymorphism and HIV-associated cardiomyopathy: a genotype-phenotype association study 

      Gasnat Shaboodien, Mark E Engel, Faisal F Syed, Joanna Poulton, Motasim Badri, Bongani M Mayosi (BioMed Central, 2009-12-01)
      Background The mitochondrial DNA (mtDNA) T16189C polymorphism, with a homopolymeric C-tract of 10–12 cytosines, is a putative genetic risk factor for idiopathic dilated cardiomyopathy in the African and British populations. ...

    • Surgical Audit 

      SWO Ogendo (Annals of African Surgery, 2010)
      No Abstract

    • Patient Willingness To Undergraduate Medical Student Involvement In Their Care At The Kenyatta National Hospital: A Cross Sectional Study. 

      STEPHEN WO Ogendo (University of Nairobi, 2010)
      Research Question: How willing are patients to the participation of medical students in their care. Objective: To determine the level of patient willingness to medical student participation in their care Design: Cross ...

    • Thromboembolic and bleeding complications in patients with prosthetic heart valves at the Kenyatta National Hospital 

      Eric Wanyutu Hungu, SWO Ogendo (Annals of African Surgery, 2012)
      Background: Despite constant monitoring of anticoagulation in prosthetic valve patients, haematologic complications occur. This study documented the occurrence of such complications and associated risk factors at the ...

    • Surgical Apgar Score Predicts Post-Laparatomy Complications 

      M Dullo, SWO Ogendo, EO Nyaim (Annals of African Surgery, 2013-09-20)
      Introduction: The Surgical Apgar score (SAS) presents a simple, immediate and an objective means of determining surgical outcomes. The score has not been widely validated in low resource settings where it would be most ...

    • Research capacity. Enabling the genomic revolution in Africa. 

      Charles Rotimi, Akin Abayomi, Alash'le Abimiku, Victoria May Adabayeri, Clement Adebamowo, Ezekiel Adebiyi, Adebowale D Ademola, Adebowale Adeyemo, Dwomoa Adu, Dissou Affolabi, Godfred Agongo, Samuel Ajayi, Sally Akarolo-Anthony, Rufus Akinyemi, Albert Akpalu, Marianne Alberts, AM Alzohairy, G Ameni, O Amodu, G Anabwani, K Andersen, F Arogundade, O Arulogun, D Asogun, R Bakare, N Balde, ML Baniecki, C Beiswanger, A Benkahla, L Bethke, M Boehnke, V Boima, J Brandful, AI Brooks, FC Brosius, C Brown, B Bucheton, DT Burke, BG Burnett, S Carrington-Lawrence, N Carstens, J Chisi, A Christoffels, R Cooper, H Cordell, N Crowther, T Croxton, J de Vries, L Derr, P Donkor, S Doumbia, A Duncanson, I Ekem, A El Sayed, ME Engel, JC Enyaru, D Everett, FM Fadlelmola, E Fakunle, KH Fischbeck, A Fischer, O Folarin, J Gamieldien, RF Garry, S Gaseitsiwe, R Gbadegesin, A Ghansah, M Giovanni, P Goesbeck, FX Gomez-Olive, DS Grant, R Grewal, M Guyer, NA Hanchard, CT Happi, S Hazelhurst, BJ Hennig, W Hide, F Hilderbrandt, C Hugo-Hamman, ME Ibrahim, R James, Y Jaufeerally-Fakim, C Jenkins, U Jentsch, PP Jiang, M Joloba, V Jongeneel, F Joubert, M Kader, K Kahn, P Kaleebu, SH Kapiga, SK Kassim, I Kasvosve, J Kayondo, B Keavney, A Kekitiinwa, SH Khan, P Kimmel, MC King, R Kleta, M Koffi, J Kopp, M Kretzler, J Kumuthini, S Kyobe, C Kyobutungi, DT Lackland, KA Lacourciere, G Landouré, R Lawlor, T Lehner, M Lesosky, N Levitt, K Littler, Z Lombard, JF Loring, S Lyantagaye, A Macleod, EB Madden, CR Mahomva, J Makani, M Mamven, M Marape, G Mardon, P Marshall, DP Martin, D Masiga, R Mason, M Mate-Kole, E Matovu, M Mayige, BM Mayosi, JC Mbanya, SA McCurdy, MI McCarthy, H McIlleron, SO Mc'Ligeyo, C Merle, AO Mocumbi, C Mondo, JV Moran, A Motala, M Moxey-Mims, WS Mpoloka, CL Msefula, T Mthiyane, N Mulder, Mulugeta Gh (Science (New York, NY), 2014-06-01)
      Our understanding of genome biology, genomics, and disease, and even human history, has advanced tremendously with the completion of the Human Genome Project. Technological advances coupled with significant cost reductions ...

    • Enabling the genomic revolution in Africa 

      Charles Rotimi, Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, (American Association for the Advancement of Science, 2014-04-20)
      Our understanding of genome biology, genomics, and disease, and even human history, has advanced tremendously with the completion of the Human Genome Project. Technological advances coupled with significant cost reductions ...

    • Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study) 

      Liesl Zühlke, Mark E Engel, Ganesan Karthikeyan, Sumathy Rangarajan, Pam Mackie, Blanche Cupido, Katya Mauff, Shofiqul Islam, Alexia Joachim, Rezeen Daniels, Veronica Francis, Stephen Ogendo, Bernard Gitura, Charles Mondo, Emmy Okello, Peter Lwabi, Mohammed M Al-Kebsi, Christopher Hugo-Hamman, Sahar S Sheta, Abraham Haileamlak, Wandimu Daniel, Dejuma Y Goshu, Senbeta G Abdissa, Araya G Desta, Bekele A Shasho, Dufera M Begna, Ahmed ElSayed, Ahmed S Ibrahim, John Musuku, Fidelia Bode-Thomas, Basil N Okeahialam, Olukemi Ige, Christopher Sutton, Rajeev Misra, Azza Abul Fadl, Neil Kennedy, Albertino Damasceno, Mahmoud Sani, Okechukwu S Ogah, Taiwo Olunuga, Huda HM Elhassan, Ana Olga Mocumbi, Abiodun M Adeoye, Phindile Mntla, Dike Ojji, Joseph Mucumbitsi, Koon Teo, Salim Yusuf, Bongani M Mayosi (Oxford University Press, 2015)
      Aims Rheumatic heart disease (RHD) accounts for over a million premature deaths annually; however, there is little contemporary information on presentation, complications, and treatment. Methods and results This ...

    • Prevalence, Associated Risk Factors and Progression Of Asymptomatic Peripheral Arterial Disease At Kenyatta National Hospital 

      NP Mehta (University of Nairobi, 2016)
      The prevalence of peripheral arterial disease worldwide has been estimated at between 4.5% and 29%. Peripheral arterial disease can be asymptomatic or symptomatic. It is an independent risk factor for cardiovascular morbidity ...