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The pesticide heptachlor affects steroid hormone secretion in isolated follicular and luteal cells of rat
(Elsevier, 2006-09-01)
Heptachlor, a chlorinated hydrocarbon pesticide, suppresses the production of
progesterone and estradiol in the female rat in vivo or in isolated ovaries in vitro. In this study
the effect of heptachlor on steroid ...
Functional characterization and protein–protein interactions of trypanosome splicing factors U2AF35, U2AF65 and SF1
(Elsevier, 2009-04-01)
Early in the assembly of the spliceosome of eukaryotes the branch-point binding protein (BBP, also called SF1) recognizes the branch point sequence, whereas the heterodimer U2AF consisting of a 65 and a 35 kDa subunit, ...
The role of echocardiography in diagnosing carditis in the setting of acute rheumatic fever
(Cambridge University Press, 2009-08)
Sir,
Vijayalakshmi and her colleagues are to be
commended for their paper.1 We disagree, however,
with the use of a scoring system to make an
echocardiographic diagnosis of carditis due to acute
rheumatic fever. We ...
The mitochondrial DNA T16189C polymorphism and HIV-associated cardiomyopathy: a genotype-phenotype association study
(BioMed Central, 2009-12-01)
Background
The mitochondrial DNA (mtDNA) T16189C polymorphism, with a homopolymeric C-tract of 10–12 cytosines, is a putative genetic risk factor for idiopathic dilated cardiomyopathy in the African and British populations. ...
A global" School for Surgeons" could help bridge the Healthcare Human Resource Crisis in Sub-Saharan Africa
(University of Nairobi, 2009)
Appropriately designed elearning programmes (including Best or School for Surgeons) may allow more efficient use of consultant teaching time. Using funding from Irish Aid, we piloted these existing e-learning tools in a ...
Rheumatic fever and rheumatic heart disease: where are we now in South Africa?: ASAP programme
(The South African Heart Association, 2009)
South Africa continues to face unacceptably high rates of rheumatic fever (RF) and rheumatic heart disease (RHD), despite readily available and inexpensive preventive measures. However, in the past several years, key players ...
Risk of conjunctival contamination from blood splashes during surgery at the Kenyatta National Hospital, Nairobi
(East African medical journal, 2008-12-15)
Objectives: To determine the utilisation rate of design specific eye protection by surgeons and to assess the risk of conjunctival contamination with blood splashes during surgery.
Design: Cross sectional, observational ...
Rachs-1 system in rist stratification for congenital heart disease surgery outcome
(East African medical journal, 2008-05-28)
Background: The Risk Adjustment in Congenital Heart Surgery (RACHS-1) system has been used as a benchmark to compare surgical results in developed countries. Its ability to stratify postoperative mortality risk has been ...
Ortner syndrome
(South African Journal of Child Health, 2008)
Ortner syndrome, or cardio-vocal syndrome, is a clinical entity characterised by hoarseness (secondary to left-sided recurrent laryngeal nerve palsy) caused by cardiovascular disease. It has been reported in up to 12% of ...
No evidence for an association between the mitochondrial variant T16189C and dilated cardiomyopathy: A systematic review and meta-analysis
(SA MEDICAL ASSOC, 2007-11-01)
No evidence for an association between the mitochondrial variant T16189C and dilated cardiomyopathy: A systematic review and meta-analysis