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Now showing items 11-20 of 25
Distinct pattern of class and subclass antibodies in immune complexes of children with cerebral malaria and severe malarial anaemia
(Blackwell Publishing Ltd, 2008)
Plasmodium falciparum infection can lead to deadly complications such as severe malaria‐associated anaemia (SMA) and cerebral malaria (CM). Children with severe malaria have elevated levels of circulating immune complexes ...
Association between sickle cell trait and low density parasitaemia among asymptomatic and parasitaemic individuals living in P. falciparum malaria Holoendemic region of Western …
(SDI, 2008)
The frequency of the mutant gene for sickle cell is widely distributed in the sub-Saharan Africa, the Middle East and the Indian subcontinent. There is epidemiologic evidence that sickle cell trait confers a survival ...
Clinical and molecular evidence for a case of Buruli ulcer (Mycobacterium ulcerans infection) in Kenya
(The American Society of Tropical Medicine and Hygiene, 2009)
Mycobacterium ulcerans infection is an emerging disease that causes indolent, necrotizing skin lesions known
as Buruli ulcer (BU) and occasional contiguous or metastatic bone lesions. Buruli ulcer is named after Buruli ...
COMPLEMENT REGULATORY PROTEIN LEVELS IN CHILDREN WITH SICKLE CELL TRAIT
(Nairobi university, 2009)
Sickle cell disease refers to a collection of autosomal recessive genetic disorders characterized by the presence of HbS variant of the globin chain while “sickle cell anaemia” refers to individuals with two copies of the ...
Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial.
(Pub Med Central, 2009-11-17)
OBJECTIVE:
RTS,S, a candidate vaccine for malaria, is a recombinant protein expressed in yeast containing part of the circumsporozoite protein (CSP) sequence of 3D7 strain of Plasmodium falciparum linked to the hepatitis ...
Pitting of malaria parasites and spherocyte formation
(Pub Med Central, 2006-07-31)
BACKGROUND:
A high prevalence of spherocytes was detected in blood smears of children enrolled in a case control study conducted in the malaria holoendemic Lake Victoria basin. It was speculated that the spherocytes ...
The role of echocardiography in diagnosing carditis in the setting of acute rheumatic fever
(Cambridge University Press, 2009-08)
Sir,
Vijayalakshmi and her colleagues are to be
commended for their paper.1 We disagree, however,
with the use of a scoring system to make an
echocardiographic diagnosis of carditis due to acute
rheumatic fever. We ...
The mitochondrial DNA T16189C polymorphism and HIV-associated cardiomyopathy: a genotype-phenotype association study
(BioMed Central, 2009-12-01)
Background
The mitochondrial DNA (mtDNA) T16189C polymorphism, with a homopolymeric C-tract of 10–12 cytosines, is a putative genetic risk factor for idiopathic dilated cardiomyopathy in the African and British populations. ...
Rheumatic fever and rheumatic heart disease: where are we now in South Africa?: ASAP programme
(The South African Heart Association, 2009)
South Africa continues to face unacceptably high rates of rheumatic fever (RF) and rheumatic heart disease (RHD), despite readily available and inexpensive preventive measures. However, in the past several years, key players ...
Risk of conjunctival contamination from blood splashes during surgery at the Kenyatta National Hospital, Nairobi
(East African medical journal, 2008-12-15)
Objectives: To determine the utilisation rate of design specific eye protection by surgeons and to assess the risk of conjunctival contamination with blood splashes during surgery.
Design: Cross sectional, observational ...