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The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis
(Springer, 2012)
Plasmodium falciparum malaria is a leading global cause of morbidity and mortality of infectious disease origin. Here, we focus largely on P. falciparum malaria in sub-Saharan Africa since this geographic region bears the ...
Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia
(Wiley Subscription Services, Inc., A Wiley Company, 2012)
In holoendemic Plasmodium falciparum transmission areas, severe malaria primarily occurs in children aged <48 months and manifests as severe malarial anemia [SMA; hemoglobin (Hb) < 6.0 g/dL]. Induction of high levels of ...