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Vitamin D status in healthy black African adults at a tertiary hospital in Nairobi, Kenya: a cross sectional study
(BioMed Central, 2018-12-01)
Vitamin D has been known since the twentieth Century for its benefits in bone health. Recent observational studies have demonstrated its benefits in infectious diseases such as tuberculosis and non-communicable diseases ...
Determination of reference intervals for common chemistry and immunoassay tests for Kenyan adults based on an internationally harmonized protocol and up-to-date statistical methods
(Public Library of Science, 2020-07-09)
Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for
40 common chemistry and immunoassay tests as part of the IFCC global RI project.
Metabolic syndrome and its predictors in an urban population in Kenya: a cross sectional study
(BioMed Central, 2017-12-01)
The metabolic syndrome (MetS) is a clustering of interrelated risk factors which doubles the risk of cardio-vascular disease (CVD) in 5–10 years and increases the risk of type 2 diabetes 5 fold. The identification of ...
Comparison of equations for estimating glomerular filtration rate in screening for chronic kidney disease in asymptomatic black Africans: a cross sectional study
(BioMed Central, 2017-12)
Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of ...
Measurement of improvement achieved by participation in international laboratory accreditation in sub-Saharan Africa: the Aga Khan University Hospital Nairobi experience
(Oxford University Press, 2014-02-02)
As part of the ISO 15189:2007 accreditation process, the Aga Khan University Hospital Nairobi laboratory became the first internationally accredited hospital laboratory in sub-Saharan Africa outside South Africa in 2011 ...
Complete blood count reference intervals from a healthy adult urban population in Kenya
(Public Library of Science, 2018-06-07)
There are racial, ethnic and geographical differences in complete blood count (CBC) blood count (CBC) and therefore it is necessary to establish RIs that are population specific. Several studies have been carried out in ...
Genetic analysis of HIV-1 subtypes in Nairobi, Kenya
(Public Library of Science, 2008-09-11)
Genetic analysis of a viral infection helps in following its spread in a given population, in tracking the routes of infection and, where applicable, in vaccine design. Additionally, sequence analysis of the viral genome ...
The effect of abdominal obesity on insulin sensitivity and serum lipid and cytokine concentrations in African women
(Blackwell Publishing Ltd, 2006-05)
Studies have shown clear associations of abdominal obesity with lipid and glucose metabolism and cytokine levels in a number of different population groups. However, no such studies have been performed in an African ...
The effect of different apo (a) isoforms on plasminogen activation in black South African subjects: cardiovascular topics
(Clinics Cardive Publishing, 2003-05-01)
The present study evaluates the effect of different apolipoprotein (a)[apo (a)] isoforms on plasminogen activation.
Biochemical and molecular diagnosis of glutaric aciduria type 1 in a black South African male child: case report
(East African medical journal, 2001)
Glutaric aciduria type I (GA-1) is an inborn error of metabolism caused by a deficiency of the mitochondrial enzyme glutaryl-Co enzyme A dehydrogenase. GA-1 is not uncommon amongst Caucasians but to the best of our knowledge, ...