Browsing Department of Biomedical Sciences by Title
Now showing items 1-20 of 91
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16S rRNA gene profiling of bacterial communities mediating production of tsetse attractive phenols in mammalian urine
(AOSIS Publishing, 2019)Several types of odours are involved in the location of host animals by tsetse (Diptera: Glossinidae), a vector of animal African trypanosomiasis. Host animals' ageing urine has been shown to be the source of a phenolic ... -
Acceptability, adherence, and clinical outcomes, of amoxicillin dispersible tablets versus oral suspension in treatment of children aged 2–59 Months with pneumonia, Kenya: A cluster randomized controlled trial
(Heliyon, 2020)Amoxicillin dispersible tablet (DT) is now recommended by the WHO as a first-line drug for the treatment of pneumonia in children below 5 years. The study aim was to compare acceptability, adherence and clinical outcome ... -
Antimalarial activity of Nigella sativa L. Seed extracts and selection of resistance in Plasmodium berghei ANKA in a mouse model
(Hindawi Limited, 2021-02-03)Chemotherapy plays a crucial role in malaria control. However, the main obstacle to treatment has been the rise of parasite resistance to most antimalarial drugs. Artemisinin-based combination therapies (ACTs) remain the ... -
Antimalarials: Review of Plasmepsins as Drug Targets and HIV Protease Inhibitors Interactions
(Bentham Science Publishers, 2018)Malaria is a major global health concern with the majority of cases reported in regions of South-East Asia, Eastern Mediterranean, Western Pacific, the Americas, and Sub-Saharan Africa. The World Health Organization (WHO) ... -
Antimicrobial Resistance Patterns of Bacteria Isolated from Wounds of Diabetic Patients at Jaramogi Oginga Odinga Teaching & Referral Hospital (JOOTRH), Kenya
(EJMED, 2022)The purpose of this study was to determine antimicrobial resistance patterns of bacteria isolated from wounds of diabetes mellitus patients at JOOTRH. A hospital based cross sectional study design was employed with a target ... -
Archaeal diversity and community structure in the compartmented gut of highert termites
(Philipps-Universität Marburg, 2013)Termites are phylogenetically divided into lower and higher termites (Inward et al., 2007). The higher termites, which constitute three quarter of all known termite species, are represented by only one family Termitidae, ... -
Assessment of Organizational Factors for Health Management Information System (HMIS) Performance in Elgeiyo Marakwet County, Kenya.
(EPH - International Journal of Medical and Health Science, 2018-03)Health Management Information Systems (HMIS) have been used by many countries using platforms adopted or own-designed. It’s implemented by integrating all healthcare services and gives service providers the ability to ... -
Assessment of palliative care services in western Kenya
(AME, 2017-01)Background: The need for palliative care services is rapidly increasing due to the rising number of patients with non-communicable diseases. The objective of this study was to assess the current availability and barriers ... -
Association between haematological parameters and sickle cell genotypes in children with Plasmodium falciparum malaria resident in Kisumu County in Western Kenya
(2020)Background: Sickle cell disease (SCD) is a monogenic disorder due to point mutation in the β-globin gene resulting in substitution of Valine for Glutamic acid. The SCD is prevalent in P. falciparum endemic regions such ... -
Barriers and Misconceptions Hindering Reduction of Intestinal Schistosomiasis in Mbita Sub-County, Western Kenya
(Research Square, 2024-02-05)Community and individual participation are crucial for the success of schistosomiasis control. The World Health Organization (WHO) has highlighted the importance of enhanced sanitation, health education, and mass treatment ... -
Barriers and Opportunities to Advancing Women in Leadership Roles in Vector Control: Perspectives from a Stakeholder Survey
(The American journal of tropical medicine and hygiene, 2018-03-19)Increasing the active participation of professional women in vector control (VC) activities may help promote greater gender equity in the workplace and reduce the burden of vector-borne diseases. This stakeholder survey ... -
Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H
(BMC, 2020)Background: Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and ... -
CHAPTER EIGHTEEN A BIORATIONALE FOR CONTROL OF BIOMPHALARIA PFEIFFERI HOST SNAILS, LARVAE OF ANOPHELES GAMBIAE AND SCHISTOSOMA MANSONI
(Cambridge Scholars Publishing, 2019-11-14)Mosquitoes transmit deadly diseases in tropical countries. Despite tremendous efforts towards disease control, the burden is still huge in endemic areas. In 2015, the region was home to 89% of malaria cases and 91% of ... -
Clinical malaria incidence and health seeking pattern in geographically heterogeneous landscape of western Kenya
(BioMed Central, 2022)Malaria remains a public health problem in Kenya despite sustained interventions deployed by the government. One of the major impediments to effective malaria control is a lack of accurate diagnosis and effective treatment. ... -
Coagulation hallmark indicators of menorrhagia in a comparative study between menorrhagic and healthy women attending Bungoma County Referral Hospital in Kenya
(Research Square, 2024-02-13)Despite the significant burden of menorrhagia among women in Western Kenya, it remains unknown whether coagulation disorders are one of the important underlying causes of this condition in the region. This study evaluated ... -
Comparative genomic and phenotypic characterization of invasive non-typhoidal Salmonella isolates from Siaya, Kenya
(PLOS, 2021)Non-typhoidal Salmonella (NTS) is a major global health concern that often causes blood stream infections in areas of the world affected by malnutrition and comorbidities such as HIV and malaria. Developing a strategy to ... -
Comparison of Different Trapping Methods to Collect Malaria Vectors Indoors and Outdoors in Western Kenya
(Research square, 2023-08-31)Enhanced vector surveillance, is one of the 4 pillars of the WHO’s global vector control response (2017–2030). Human landing catches are the gold standard for entomological surveys but are difficult to implement and expose ... -
Compartment-specific bacterial communities in higher termites
(M icroha bitat-specificity of the hindgut microbiota in higher termites, 2013)The higher termite gut is a highly structured habitat and shows the presence of spatially separated compartments. The differences in physicochemical parameters between the compartments, most importantly pH, play an important ... -
Comprehensive Transcriptome and Mutational Profiling of Endemic Burkitt Lymphoma Reveals EBV Type–Specific Differences
(OnlineFirst, 2017)e most common pedi atric cancer in malaria-endemic equatorial Africa and nearly always contains Epstein–Barr virus (EBV), unlike sporadic Burkitt lymphoma (sBL) that occurs with a lower incidence in developed countries. ... -
CRITICAL FACTORS AND CREDIT UPTAKE IN YOUTH ENTERPRISE DEVELOPMENT FUND IN SUNA EAST CONSTITUENCY, MIGORI COUNTY, KENYA
(KENYATTA UNIVERSITY, 2018-11)Youth entrepreneurship in Kenya plays a significant role in enhancing Kenya’s economic development and in reducing youth unemployment. Despite the great significance of entrepreneurship in Kenya, there is a high failure ...
