Browsing Department of Biomedical Sciences by Title
Now showing items 58-77 of 88
-
Knowledge, Perceptions, and Practice of Nurses on Surveillance of Adverse Events following Childhood Immunization in Nairobi, Kenya
(Hindawi Publishing Corporation, 2016)Although vaccines currently approved for routine childhood immunization are safe and effective, frequent adverse events following immunization often cause illnesses and sometimes loss of public trust in immunization ... -
Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria
(Frontier in Immunology, 2018)Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is known about human immune responses to ... -
Low sensitivity of the careHPV™ Assay for detection of Oncogenic Human Papillomavirus in cervical samples from HIV-infected and HIV-uninfected Kenyan women
(HSPC, 2020)Human papillomavirus (HPV) infection causes cervical cancer (CC), a common malignancy among Kenyan women. New CC screening methods rely on oncogenic HPV (“highrisk”, or HR-HPV) detection, but most have not been evaluated ... -
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
(Nature Communications, 2021)A highly protective vaccine will greatly facilitate achieving and sustaining malaria elimination. Understanding mechanisms of antibody-mediated immunity is crucial for developing vaccines with high efficacy. Here, we ... -
Metabollic syndrome components as a risk factor to the health status of university students in Kenya
(IJCIRAS, 2019)An efficient healthcare system targets the maintenance or improving the health position for citizens that can be achieved through disease and illness prevention based on curative and preventive care. Kenya currently ... -
Metagenomic analysis of the microbiota in the highly compartmented hindguts of six wood-or soil-feeding higher termites
(BioMed Central, 2015-12-01)Termites are important contributors to carbon and nitrogen cycling in tropical ecosystems. Higher termites digest lignocellulose in various stages of humification with the help of an entirely prokaryotic microbiota housed ... -
“Methanoplasmatales,” Thermoplasmatales-related archaea in termite guts and other environments, are the seventh order of methanogens
(American Society for Microbiology, 2012-12-01)The Euryarchaeota comprise both methanogenic and nonmethanogenic orders and many lineages of uncultivated archaea with unknown properties. One of these deep-branching lineages, distantly related to the Thermoplasmatales, ... -
Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling
(science direct, 2019)Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory receptor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe malarial anaemia ... -
Non-Puerperal Uterine Inversion in a Young Woman: A Case Report, Brief Surgical Review, and Clinical Insights
(Clinical Medical Reviews and Case Reports, 2016-08) -
Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe malarial anemia in kenyan children
(Frontiers, 2022)Severe malarial anemia (SMA; Hb < 5.0 g/dl) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions such as western Kenya. -
Optimization of growth conditions and characterization of enzymatic activity of selected novel Streptomyces species from Kenyan soils
(Scientific Conference Proceedings, 2012-06-14)This study was aimed at unveiling and assessing protease, esterase, amylase and lipase enzymes from selected novel Streptomyces species with biotechnological interest. Four Streptomyces isolates from Jomo Kenyatta University ... -
Phylogeography and population structure of the tsetse fly Glossina pallidipes in Kenya and the Serengeti ecosystem
(PLOS, 2020)Glossina pallidipes is the main vector of animal African trypanosomiasis and a potential vector of human African trypanosomiasis in eastern Africa where it poses a large economic burden and public health threat. Vector ... -
The Potential of Differentiation Related Gene 1 DRG1) as a Biomarker for Metastasis of Estrogen Receptor Positive Breast Cancer
(Journal of Advances in Medicine and Medical Research, 2021-10-07)Breast cancer is major burden worldwide and the majority of breast cancers express estrogen receptors (ER) suggesting a high dependence on estrogen hormone. Age is among the major determinants of breast cancer development, ... -
Prevalence and detection of drug resistant mutations in Mycobacterium tuberculosis among drug naïve patients in Nairobi, Kenya
(BioMed Central, 2019-12)Tuberculosis (TB), an ancient scourge of humanity known for several thousands of years, is still a significant public health challenge in many countries today even though some progress has been made in recent years in ... -
The prevalence and management strategies of gestational urinary tract infections (UTI) in Kisumu County, Kenya
(Cold Spring Harbor Laboratory Press, 2022)Urinary tract infections (UTI) contribute to substantive proportions of adverse pregnancy outcomes. Current national statistics in Kenya show high maternal mortality (488/100,000) and neonatal mortality (24/1,000) rates. ... -
Prevalence of food insecurity in patients with diabetes in western Kenya.
(Wiley, 2013-06)Aims To determine the characteristics of patients with diabetes who reported food insecurity at three diabetes clinics in western Kenya. Methods This study includes routinely collected demographic data at the first ... -
Prevalence of preconception care provision in Kisumu county-Kenya
(Cold Spring Harbor Laboratory Press, 2022)‘Preconception care’ (PCC) is the provision of biomedical, behavioral and social health interventions to women and couples before conception occurs. The PCC, is valuable and key in preventing and controlling non-communicable ... -
Profiling genome-wide recombination in Epstein Barr virus reveals type-specific patterns and associations with endemic-Burkitt lymphoma
(BioMed Central, 2022-12)Endemic Burkitt lymphoma (eBL) is potentiated through the interplay of Epstein Barr virus (EBV) and holoendemic Plasmodium falciparum malaria. To better understand EBV’s biology and role in eBL, we characterized genome-wide ... -
Pyrethroid resistance in Anopheles gambiae s.s. and Anopheles arabiensis in western Kenya: phenotypic, metabolic and target site characterizations of three populations
(Wiley Online Library, 2012)Field and laboratory investigations revealed phenotypic, target site and metabolic resistance to permethrin in an Anopheles gambiae s.s. (Diptera: Culicidae) population in Bungoma District, a region in western Kenya in ... -
Qualitative analysis of phytoconstituents in tragia brevipes plant
(International Journal of Pharmaceutical Research & Analysis, 2013)The study was conducted to analyze the phytoconstituents of Tragia brevipes plant leaves. The plant samples were extracted using methanol and water in the ratio 9:1. The phytoconstituents study was done using standard ...