• Clinical malaria incidence and health seeking pattern in geographically heterogeneous landscape of western Kenya 

  Wilfred Ouma Otambo, Patrick O Onyango, Kevin Ochwedo, Julius Olumeh, Shirley A Onyango, Pauline Orondo, Harrysone Atieli, Ming-Chieh Lee, Chloe Wang, Daibin Zhong, Andrew Githeko, Guofa Zhou, John Githure, Collins Ouma, Guiyun Yan, James Kazura (BioMed Central, 2022)

  Malaria remains a public health problem in Kenya despite sustained interventions deployed by the government. One of the major impediments to effective malaria control is a lack of accurate diagnosis and effective treatment. ...
• Antimicrobial Resistance Patterns of Bacteria Isolated from Wounds of Diabetic Patients at Jaramogi Oginga Odinga Teaching & Referral Hospital (JOOTRH), Kenya 

  Susan Mamusavu Tuvei, Bernard Guyah, Rose Kakai (EJMED, 2022)

  The purpose of this study was to determine antimicrobial resistance patterns of bacteria isolated from wounds of diabetes mellitus patients at JOOTRH. A hospital based cross sectional study design was employed with a target ...
• Impact of integrated water, sanitation, hygiene, health and nutritional interventions on diarrhoea disease epidemiology and microbial quality of water in a resource-constrained setting in Kenya: A controlled intervention study 

  Ernest Apondi Wandera, Betty Muriithi, Cyrus Kathiiko, Felix Mutunga, Mary Wachira, Maurine Mumo, Anne Mwangi, Joseph Tinkoi, Mirasine Meiguran, Pius Akumu, Valeria Ndege, Fredrick Kasiku, James Ang'awa, Ryoichiro Mochizuki, Satoshi Kaneko, Kouichi Morita, Collins Ouma, Yoshio Ichinose (Wiley online library, 2022)

  We assessed the impact of water, hygiene and sanitation (WASH), maternal,new-born and child health (MNCH), nutrition and early childhood development (ECD) on diarrhoea and microbial quality of water in a resource-constrained ...
• Genetic differentiation in East African ethnicities and its relationship with endurance running success 

  André LS Zani, Mateus H Gouveia, Marla M Aquino, Rodrigo Quevedo, Rodrigo L Menezes, Charles Rotimi, Gerald O Lwande, Collins Ouma, Ephrem Mekonnen, Nelson JR Fagundes (Public Library of Science, 2022)

  Since the 1960s, East African athletes, mainly from Kenya and Ethiopia, have dominated long-distance running events in both the male and female categories. Further demographic studies have shown that two ethnic groups are ...
• Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe malarial anemia in kenyan children 

  Evans Raballah, Kristen Wilding, Samuel B Anyona, Elly O Munde, Ivy Hurwitz, Clinton O Onyango, Cyrus Ayieko, Christophe G Lambert, Kristan A Schneider, Philip D Seidenberg, Collins Ouma, Benjamin H McMahon, Qiuying Cheng, Douglas J Perkins (Frontiers, 2022)

  Severe malarial anemia (SMA; Hb < 5.0 g/dl) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum transmission regions such as western Kenya.
• The prevalence and management strategies of gestational urinary tract infections (UTI) in Kisumu County, Kenya 

  Eunice Namuyenga Toko, Shivanthi Samarasinghe, Esther Furaha, Tariq Kapasi, Collins Ouma (Cold Spring Harbor Laboratory Press, 2022)

  Urinary tract infections (UTI) contribute to substantive proportions of adverse pregnancy outcomes. Current national statistics in Kenya show high maternal mortality (488/100,000) and neonatal mortality (24/1,000) rates. ...
• Prevalence of preconception care provision in Kisumu county-Kenya 

  Everlyne N Morema, Morris Senghor, Collins Ouma (Cold Spring Harbor Laboratory Press, 2022)

  ‘Preconception care’ (PCC) is the provision of biomedical, behavioral and social health interventions to women and couples before conception occurs. The PCC, is valuable and key in preventing and controlling non-communicable ...
• Evidence of co-exposure with Brucella spp, Coxiella burnetii, and Rift Valley fever virus among various species of wildlife in Kenya 

  Francis Gakuya1☯, James AkokoID2,3☯*, Lillian Wambua2 , Richard Nyamota2 , Bernard Ronoh4 , Isaac Lekolool4 , Athman Mwatondo2,5,6, Mathew Muturi2,5,7, Collins Ouma3 , Daniel Nthiwa8 , Earl Middlebrook9 , Jeanne Fair9 , John Gachohi10,11, Kariuki Njenga10, Bernard Bett2 (Public Library of Science, 2022-09)

  Co-infection, especially with pathogens of dissimilar genetic makeup, may result in a more devastating impact on the host. Investigations on co-infection with neglected zoonotic pathogens in wildlife are necessary to ...
• Influence of landscape heterogeneity on entomological and parasitological indices of malaria in Kisumu, Western Kenya 

  Wilfred Ouma Otambo, Patrick O Onyango, Chloe Wang, Julius Olumeh, Benyl M Ondeto, Ming-Chieh Lee, Harrysone Atieli, Andrew K Githeko, James Kazura, Daibin Zhong, Guofa Zhou, John Githure, Collins Ouma, Guiyun Yan (BioMed Central, 2022)

  Identification and characterization of larval habitats, documentation of Anopheles spp. composition and abundance, and Plasmodium spp. infection burden are critical components of integrated vector management. The present ...
• Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region of Kenya 

  Lily E Kisia, Qiuying Cheng, Evans Raballah, Elly O Munde, Benjamin H McMahon, Nick W Hengartner, John M Ong’echa, Kiprotich Chelimo, Christophe G Lambert, Collins Ouma, Prakasha Kempaiah, Douglas J Perkins, Kristan A Schneider, Samuel B Anyona (BioMed Central, 2022)

  Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31.1, the colony-stimulating factor 2 gene (CSF2) encodes granulocyte ...
• Sero-Prevalence and Molecular Analysis of Brucellosis in Livestock Keepers and Domestic Ruminants in Baringo County, Kenya 

  Peter N Lokamar, Moses A Kutwah, Elly O Munde, Dickens Oloo, Harrysone Atieli, Sussy Gumo, James M Akoko, Collins Ouma (Research square, 2022)

  Brucellosis is widely distributed in more than 170 countries around the world, where it poses a huge threat to animal husbandry and human health. Brucellosis is a worldwide re-emerging zoonotic disease that poses serious ...
• Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling 

  Angela O.Achienga, Bernard Guyah,Qiuying Cheng,John M.Ong'echa,Collins Ouma,Christophe G.Lambert,Douglas J.Perkins (science direct, 2019)

  Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory receptor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe malarial anaemia ...
• The diagnostic accuracy of Th1 (IFN-γ, TNF-α, and IL-2) and Th2 (IL-4, IL-6 and IL-10) cytokines response in AFB microscopy smear negative PTB- HIV co-infected patients 

  Kisuya J., Chemtai A., Raballah E., Keter A. & Ouma C (Springer, 2019)

  Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory diagnostic technique for Pulmonary Tuberculosis (PTB) in low-and-middle income countries. Although it is highly specifc, the sensitivity ...
• Low sensitivity of the careHPV™ Assay for detection of Oncogenic Human Papillomavirus in cervical samples from HIV-infected and HIV-uninfected Kenyan women 

  Titus M, Ermel A, Moormann A, Cu-Uvin S, Orang’o O, Tonui P, Chelimo K, Rosen B, Itsura P, Muthoka K, Loehrer P, Ong’echa JM and Brown DR (HSPC, 2020)

  Human papillomavirus (HPV) infection causes cervical cancer (CC), a common malignancy among Kenyan women. New CC screening methods rely on oncogenic HPV (“highrisk”, or HR-HPV) detection, but most have not been evaluated ...
• Incidence of Brucella infection in various livestock species raised under the pastoral production system in Isiolo County, Kenya 

  Josiah Njeru, Daniel Nthiwa, James Akoko, Harry Oyas & Bernard Bett (Springer, 2021)

  We implemented a longitudinal study to determine the incidence of Brucella infection in cattle, camels, sheep and goats that were being raised in a pastoral area in Isiolo County, Kenya. An initial cross-sectional survey ...
• Phylogeography and population structure of the tsetse fly Glossina pallidipes in Kenya and the Serengeti ecosystem 

  Bateta R, Saarman NP, Okeyo WA, DionK, Johnson T, Mireji PO, Okoth S., Malele I., Murilla G., Aksoy S., Adalgisa C. (PLOS, 2020)

  Glossina pallidipes is the main vector of animal African trypanosomiasis and a potential vector of human African trypanosomiasis in eastern Africa where it poses a large economic burden and public health threat. Vector ...
• Determinants of tuberculosis treatment interruption among patients in Vihiga County, Kenya 

  Paul Waliaula Wekunda , Dickens S. Omondi Aduda,Bernard Guyah (PLOS ONE, 2021)

  Despite robust Tuberculosis (TB) program with effective chemotherapy and high coverage, treatment interruption remains a serious problem. Interrupting TB treatment means that patients remain infectious for longer time ...
• Synergism in Antiplasmodial Activities of Artemether and Lumefantrine in Combination with Securidaca longipedunculata Fresen (Polygalaceae) 

  Douglas O. Ochora , Esezah K. Kakudidi , Jane Namukobe , Perpetua Ipulet , Dancan M. Wakoli , Winnie Okore , Edwin W. Mwakio , Redempthah A. Yeda , Agnes C. Cheruiyot , Dennis W. Juma , Ben Andagalu , Amanda L. Roth , Bernhards R. Ogutu , Abiy Yenesew and Hoseah M. Akala (MDPI, 2021)

  Malaria is the most lethal parasitic disease in the world. The frequent emergence of resistance by malaria parasites to any drug is the hallmark of sustained malaria burden. Since the deployment of artemisinin-based ...
• Immunohistochemical Analysis of Prostein Expression in Archived Prostatic Core Biopsies from Prostate Cancer Patients in Western Kenya 

  Omondi Swaya Tyrus, Dedan Opondo,David O. Benard Guyah,Ng’wena Gideon Magak (Research Square, 2021)

  Prostate cancer is the leading cause of cancer-associated mortality in men. Most of the current biomarkers for detection of the disease have low sensitivity and specificity. Prostein is a newly reported prostate cancer ...
• Effects of Achyranthes aspera, Bidens pilosa and Ajuga remota Leaf extracts on the blood glucose levels and hemoparameters in male goats treated with Alloxan 

  WO Opiyo , AGM Ngwena, AVO Ofulla (AJOL, 2021)

  Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus the disease constitutes a major health concern. Presently, it is an incurable metabolic disorder which affects about 2.8% of the global ...

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