Browsing Department of Biomedical Sciences by Title
Now showing items 62-81 of 81
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Optimization of growth conditions and characterization of enzymatic activity of selected novel Streptomyces species from Kenyan soils
(Scientific Conference Proceedings, 2012-06-14)This study was aimed at unveiling and assessing protease, esterase, amylase and lipase enzymes from selected novel Streptomyces species with biotechnological interest. Four Streptomyces isolates from Jomo Kenyatta University ... -
Phylogeography and population structure of the tsetse fly Glossina pallidipes in Kenya and the Serengeti ecosystem
(PLOS, 2020)Glossina pallidipes is the main vector of animal African trypanosomiasis and a potential vector of human African trypanosomiasis in eastern Africa where it poses a large economic burden and public health threat. Vector ... -
The Potential of Differentiation Related Gene 1 DRG1) as a Biomarker for Metastasis of Estrogen Receptor Positive Breast Cancer
(Journal of Advances in Medicine and Medical Research, 2021-10-07)Breast cancer is major burden worldwide and the majority of breast cancers express estrogen receptors (ER) suggesting a high dependence on estrogen hormone. Age is among the major determinants of breast cancer development, ... -
Prevalence and detection of drug resistant mutations in Mycobacterium tuberculosis among drug naïve patients in Nairobi, Kenya
(BioMed Central, 2019-12)Tuberculosis (TB), an ancient scourge of humanity known for several thousands of years, is still a significant public health challenge in many countries today even though some progress has been made in recent years in ... -
The prevalence and management strategies of gestational urinary tract infections (UTI) in Kisumu County, Kenya
(Cold Spring Harbor Laboratory Press, 2022)Urinary tract infections (UTI) contribute to substantive proportions of adverse pregnancy outcomes. Current national statistics in Kenya show high maternal mortality (488/100,000) and neonatal mortality (24/1,000) rates. ... -
Prevalence of food insecurity in patients with diabetes in western Kenya.
(Wiley, 2013-06)Aims To determine the characteristics of patients with diabetes who reported food insecurity at three diabetes clinics in western Kenya. Methods This study includes routinely collected demographic data at the first ... -
Prevalence of preconception care provision in Kisumu county-Kenya
(Cold Spring Harbor Laboratory Press, 2022)‘Preconception care’ (PCC) is the provision of biomedical, behavioral and social health interventions to women and couples before conception occurs. The PCC, is valuable and key in preventing and controlling non-communicable ... -
Profiling genome-wide recombination in Epstein Barr virus reveals type-specific patterns and associations with endemic-Burkitt lymphoma
(BioMed Central, 2022-12)Endemic Burkitt lymphoma (eBL) is potentiated through the interplay of Epstein Barr virus (EBV) and holoendemic Plasmodium falciparum malaria. To better understand EBV’s biology and role in eBL, we characterized genome-wide ... -
Pyrethroid resistance in Anopheles gambiae s.s. and Anopheles arabiensis in western Kenya: phenotypic, metabolic and target site characterizations of three populations
(Wiley Online Library, 2012)Field and laboratory investigations revealed phenotypic, target site and metabolic resistance to permethrin in an Anopheles gambiae s.s. (Diptera: Culicidae) population in Bungoma District, a region in western Kenya in ... -
Qualitative analysis of phytoconstituents in tragia brevipes plant
(International Journal of Pharmaceutical Research & Analysis, 2013)The study was conducted to analyze the phytoconstituents of Tragia brevipes plant leaves. The plant samples were extracted using methanol and water in the ratio 9:1. The phytoconstituents study was done using standard ... -
Reactive case detection of Plasmodium falciparum in western Kenya highlands: effective in identifying additional cases, yet limited effect on transmission
(BioMed Central, 2018-03-13)Background: Identifying asymptomatic reservoirs of malaria parasites using index cases as entry points into the community is potentially a cost-efective way towards achieving malaria elimination. Methods: Within 1 year, ... -
Safe Anesthesia Care in Western Kenya: A Preliminary Assessment of the Impact of Nurse Anesthetists at Multiple Levels of Government Hospitals
(International Anesthesia Research, 2019)BACKGROUND: Only 20% of the surgical burden in eastern sub-Saharan Africa is currently met, leaving >17 million surgical cases annually in need of safe surgery and anesthesia. Similarly, there is an extreme shortage of ... -
Seasonality of associations between production of indigenous foods and food security status of mother-child dyads in Kisumu County, Kenya
(BioMed Central, 2024-01-10)Food insecurity is a major predicament for rural populations, especially mothers and children, whose livelihoods are often dependent on rain-fed agriculture. Indigenous foods have the potential of mitigating food insecurity ... -
Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia
(Scientific Report, 2019)Epstein Barr virus (EBV) is the etiologic agent involved in numerous human cancers. After infecting the host, EBV establishes a latent infection, with low levels of messenger RNA (mRNA) and protein expression, evolved ... -
Sero-Prevalence and Molecular Analysis of Brucellosis in Livestock Keepers and Domestic Ruminants in Baringo County, Kenya
(Research square, 2022)Brucellosis is widely distributed in more than 170 countries around the world, where it poses a huge threat to animal husbandry and human health. Brucellosis is a worldwide re-emerging zoonotic disease that poses serious ... -
Seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya
(BioMed Central, 2018-03-12)Since the implementation of a series of blood donation safety improvements in Kenya, information about seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors especially in high ... -
Status of aflatoxin contamination in cow milk produced in smallholder dairy farms in urban and peri-urban areas of Nairobi County: a case study of Kasarani sub county, Kenya
(Taylor & Francis, 2018)Introduction: Milk consumption in Kenya supersedes other countries in East Africa. However, milk contamination with aflatoxin M1 (AFM1) is common, but the magnitude of this exposure and the health risks are poorly ... -
Synergism in Antiplasmodial Activities of Artemether and Lumefantrine in Combination with Securidaca longipedunculata Fresen (Polygalaceae)
(MDPI, 2021)Malaria is the most lethal parasitic disease in the world. The frequent emergence of resistance by malaria parasites to any drug is the hallmark of sustained malaria burden. Since the deployment of artemisinin-based ... -
Trends of non-vaccination, under-vaccination and missed opportunities for vaccination (2003–2014) amongst children 0–23 months in Kenya
(Public Library of Science, 2024-02-06)Vaccines are effective and cost-effective. Non-vaccination, under-vaccination, and missed opportunities for vaccination (MOV), have contributed to incomplete vaccination coverage in Kenya. Analyzing their trends is essential ... -
Young Adults in Endemic Areas: An Untreated Group in Need of School-Based Preventive Chemotherapy for Schistosomiasis Control and Elimination
(Tropical Medicine and Infectious Disease, 2018)Parasitologic surveys of young adults in college and university settings are not commonly done, even in areas known to be endemic for schistosomiasis and soil-transmitted helminths. We have done a survey of 291 students ...