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Pyrethroid susceptibility of malaria vectors in four Districts of western Kenya

Ochomo, Eric; Bayoh, Nabie M; Kamau, Luna; Atieli, Francis; Vulule, John; Ouma, Collins; Ombok, Maurice; Njagi, Kiambo; Soti, David; Mathenge, Evan; Muthami, Lawrence; Kinyari, Teresa; Subramaniam, Krishanthi; Kleinschmidt, Immo; Donnelly, Martin J; Mbogo, Charles (BioMed Central, 2014-07-04)

Increasing pyrethroid resistance in malaria vectors has been reported in western Kenya where long lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the mainstays of vector control. To ensure the ...

Sickle cell trait is not associated with endemic Burkitt lymphoma: An ethnicity and malaria endemicity‐matched case–control study suggests factors controlling EBV...

Mulama, David H; Bailey, Jeffrey A; Foley, Joslyn; Chelimo, Kiprotich; Ouma, Collins; Jura, Walter G; Otieno, Juliana; Vulule, John; Moormann, Ann M (2014-02)

Endemic Burkitt lymphoma (eBL) is associated with Epstein–Barr virus (EBV) and Plasmodium falciparum coinfections. Malaria appears to dysregulate immunity that would otherwise control EBV, thereby contributing to eBL ...

Determinants of cervical screening services uptake among 18–49 year old women seeking services at the Jaramogi Oginga Odinga Teaching and Referral Hospital,...

Morema, Everlyne N; Atieli, Harrysone E; Onyango, Rosebella O; Omondi, Joyce H; Ouma, Collins (BioMed Central, 2014-08-06)

Kenyan women aged≥ 15 years are at risk of developing cervical cancer. Currently, cervical cytology reduces cervical cancer incidence, since it allows for early diagnosis and treatment. Uptake of cervical screening ...

Access to artemisinin-based combination therapy (ACT) and quinine in malaria holoendemic regions of western Kenya

Watsierah, Carren A; Ouma, Collins (BioMed Central, 2014-07-28)

Artemisinin-based combination therapy (ACT) has been adopted as the most effective treatment against malaria in many endemic countries like Kenya while quinine has remained the second line. The objective of the current ...

A non-synonymous polymorphism in IL-23R Gene (rs1884444) is associated with reduced risk to schistosomiasis-associated Immune Reconstitution Inflammatory S...

Ogola, George O; Ouma, Collins; Jura, Walter G; Muok, Erick O; Colebunders, Robert; Mwinzi, Pauline N (BioMed Central, 2014-06-10)

Background Human Immunodeficiency Virus (HIV) and Schistosomiasis co-infection is common among residents at the shores of Lake Victoria in Kenya. About 36% of this population initiating antiretroviral therapy (ART) ...

Clinical chemistry profiles in injection heroin users from Coastal Region, Kenya

Were, Tom; Wesongah, Jesca O; Munde, Elly; Ouma, Collins; Kahiga, Titus M; Owuor, Francisca O; Kiarie, James N; Ahmed, Aabid A; Makokha, Ernest P; Budambula, Valentine (Biomed central, 2014-07-09)

Background Although the co-burden of injection drug use and HIV is increasing in Africa, little is known about the laboratory markers of injection drug use and anti-retroviral treatment (ART) in Kenyan injection drug ...

Changes in antigen-specific cytokine and chemokine responses to Plasmodium falciparum antigens in a highland area of Kenya after a prolonged absence of malari...

Ochola, Lyticia A; Ayieko, Cyrus; Kisia, Lily; Ng'wena, G Magak; Shabani, Estela; Ouma, Collins; John, Chandy C (American Society for Microbiology, 2014-09-01)

Individuals naturally exposed to Plasmodium falciparum lose clinical immunity after a prolonged lack of exposure. P. falciparum antigen-specific cytokine responses have been associated with protection from clinical ...

Efficacy of long lasting insecticidal nets compromised by insecticide resistance

Ochomo, Eric O; Bayoh, Nabie M; Walker, Edward D; Abongo, Bernard O; Ombok, Maurice O; Ouma, Collins; Githeko, Andrew K; Vulul, John; Yan, Guiyun; Gimnig, John E (Research Information Ltd, 2014-01-01)

Malaria control is heavily reliant on the use of insecticides given that the two most common control tools, long lasting insecticidal nets (LLIN) and indoor residual sprays are both insecticide based. Of these, the ...

Seroprevalence of anti-dengue virus 2 serocomplex antibodies in out-patients with fever visiting selected hospitals in rural parts of western Kenya in 2010-2011: a cr...

Awando, Janet A; Ongus, Juliette R; Ouma, Collins; Mwau, Matilu (African Field Epidemiology Network, 2014)

There has been a recent increase in the spread of dengue to rural areas. Rural parts of western kenya are naturally prone to mosquito-borne diseases, however, limited research has been documented on infections with ...

Interleukin-6 and interleukin-10 gene promoter polymorphisms and risk of endemic Burkitt lymphoma

Oduor, Cliff I; Chelimo, Kiprotich; Ouma, Collins; Mulama, David H; Foley, Joslyn; Vulule, John; Bailey, Jeffrey A; Moormann, Ann M (The American Society of Tropical Medicine and Hygiene, 2014-09-03)

Overexpression of interleukin-6 (IL-6) and IL-10 in endemic Burkitt lymphoma (eBL) may facilitate tumorigenesis by providing a permissive cytokine milieu. Promoter polymorphisms influence interindividual differences ...