Seroprevalence of anti-dengue virus 2 serocomplex antibodies in out-patients with fever visiting selected hospitals in rural parts of western Kenya in 2010-2011: a cr...

Abstract

There has been a recent increase in the spread of dengue to rural areas. Rural parts of western kenya are naturally prone to mosquito-borne diseases, however, limited research has been documented on infections with dengue. This study therefore investigated the presence of antibodies against dengue virus 2 (denv-2) in a cross- section of febrile out-patients visiting three selected hospitals to assess the level of exposure and to possibly identify the epidemiologic and clinical factors of seropositive participants. Methods: In a cross-sectional study, we administered a questionnaire and used indirect elisa to test for the presence of denv-2 antibodies in febrile outpatients (n= 422) visiting three selected hospitals in rural western kenya. All positive and borderline samples were re- evaluated by plaque reduction neutralization tests (prnt). Results: The prevalence of denv …