Efficacy of long lasting insecticidal nets compromised by insecticide resistance
Publication Date
2014-01-01Author
Ochomo, Eric O
Bayoh, Nabie M
Walker, Edward D
Abongo, Bernard O
Ombok, Maurice O
Ouma, Collins
Githeko, Andrew K
Vulul, John
Yan, Guiyun
Gimnig, John E
Metadata
Show full item recordAbstract/ Overview
Malaria control is heavily reliant on the use of insecticides given that the two most
common control tools, long lasting insecticidal nets (LLIN) and indoor residual sprays are
both insecticide based. Of these, the LLINs have only one class of insecticides approved for
use in net treatment, the pyrethroids. Insecticide resistance especially to pyrethroids, has
emerged and now spread to many parts of sub-Saharan Africa where LLIN and IRS are
central to malaria vector control and consequently threatens these vital programs. In a study
conducted in western Kenya in an area with high levels of pyrethroid resistance, live
Anopheles mosquitoes were routinely observed resting inside nets. Pyrethroid resistance
has been spreading rapidly in sub-Saharan Africa and has been documented in 23
countries. This may partly be in response to agricultural application and run-off of …