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Defects in resting metabolic rates and mitochondrial respiration in Kwashiorkor and dietary obese rats

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dc.contributor.author Konji, Victor N
dc.contributor.author Olowookere, Julius O
dc.contributor.author Makawiti, Dominic W
dc.contributor.author Kamau, John MZ
dc.contributor.author Kiaira, Job K
dc.contributor.author Omwandho, Charles A
dc.date.accessioned 2018-03-29T11:53:15Z
dc.date.available 2018-03-29T11:53:15Z
dc.date.issued 1991-07-01
dc.identifier.uri https://repository.maseno.ac.ke/handle/123456789/431
dc.description.abstract Resting metabolic rates have been measured and compared with hepatic mitochondrial respiration in Kwashiorkor and diet-induced obese weaned rats. In Kwashiorkor, resting metabolic rate was 21% lower than the value of controls, while that of the obese rats was 14% higher than in control animals. The resting metabolic rate for Kwashiorkor animals was 50% of the predicted basal metabolic rate (BMR), whereas that of the obese rats was 23% higher than the predicted BMR. The mitochondrial oxygen consumption patterns, using malate plus glutamate or succinate as respiratory substrates, revealed that the resting respiration (state 4) was 23.9% higher in Kwashiorkor and 29.1% higher in obese animals, while the active (state 3) respiration was 34.8% lower in Kwashiorkor and 43.3% lower in obese rats compared to controls. The respiratory control … en_US
dc.publisher Springer-Verlag en_US
dc.title Defects in resting metabolic rates and mitochondrial respiration in Kwashiorkor and dietary obese rats en_US
dc.type Article en_US


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