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dc.contributor.authorBorus, Pk
dc.contributor.authorNyindo, M
dc.contributor.authorFarah, IO
dc.contributor.authorOguya, FO
dc.contributor.authorMakawiti, Dominic W
dc.description.abstractVaccination of five baboons with an anti-idiotypic vaccine to irradiated Schistosoma mansoni cercariae resulted in nearly 19% protection compared to 39% protection conferred to five baboons vaccinated with an irradiated vaccine. Vaccination with the anti-idiotypic antibodies resulted in a significant reduction of pathology and granuloma size following challenge with live unattenuated cercariae. Results presented in this work are considered highly significant because the anti-idiotypic vaccine markedly influenced schistosomiasis morbidity which is the main consideration in this disease.en_US
dc.publisherBlackwell Publishing Ltden_US
dc.titleSehistosoma Mansoni in the Baboon: Modulation of Pathology After Vaccination with Polyclonal Anti‐Idiotypic Antibodiesen_US

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