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Thyroid status and adenosine triphosphataseactivity in experimental Trypanosoma congolense infection in rabbits

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dc.contributor.author Lomo, Po
dc.contributor.author Makawiti, Dominic W
dc.contributor.author Okinji, VN
dc.date.accessioned 2018-03-29T08:02:58Z
dc.date.available 2018-03-29T08:02:58Z
dc.date.issued 1996-11-01
dc.identifier.uri https://repository.maseno.ac.ke/handle/123456789/425
dc.description.abstract Summary The effect of trypanosome infection on the plasma levels and ratios of tri- iodothyronine (T 3) and thyroxine (T 4) as well as the activity of mitochondrial adenosine triphosphatase (ATPase) were investigated. Three groups of sexually mature white New Zealand rabbits were used. Group 1 consisted of the normal non-infected rabbits, group 2 were experimentally infected with Trypanosoma congolense and group 3 were infected but given replacement doses of thyroxine. The infected animals (group 2) showed a rapid decline in both T 3 and T 4 but an increase in the T 3/T 4 ratio indicating differential production or clearance rates between the two hormones. The mitochondrial ATPase activity was found to be depressed in the infected group whereas there was no significant difference in the ATPase activity between the non-infected (group 1) and infected-treated animals … en_US
dc.publisher Saunders en_US
dc.title Thyroid status and adenosine triphosphataseactivity in experimental Trypanosoma congolense infection in rabbits en_US
dc.type Article en_US


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