School of Medicine: Recent submissions
Now showing items 21-40 of 566
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Perceived acceptability of self-administered topical therapy for cervical precancer treatment among women undergoing cervical cancer screening in Kenya
(Cold Spring Harbor Laboratory Press, 2024-03-05)Innovative strategies are urgently needed to meet the World Health Organizations 2030 target of treating 90% of women with precancerous cervical lesions, especially in countries most affected by cervical cancer. We assessed ... -
A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa
(Nature Publishing Group UK, 2023-10-23)Invasive non-typhoidal Salmonella (iNTS) disease manifesting as bloodstream infection with high mortality is responsible for a huge public health burden in sub-Saharan Africa. Salmonella enterica serovar Typhimurium (S. ... -
Time to full enteral feeds in hospitalised preterm and very low birth weight infants in Nigeria and Kenya
(Public Library of Science, 2024-03-08)Preterm (born < 37 weeks’ gestation) and very low birthweight (VLBW; <1.5kg) infants are at the greatest risk of morbidity and mortality within the first 28 days of life. Establishing full enteral feeds is a vital aspect ... -
Diversity and taxonomic revision of methanogens and other archaea in the intestinal tract of terrestrial arthropods
(Frontiers, 2023-11-11)Methane emission by terrestrial invertebrates is restricted to millipedes, termites, cockroaches, and scarab beetles. The arthropod-associated archaea known to date belong to the orders Methanobacteriales, Methanomassiliicoccales, ... -
Characterization of Anopheles funestus Larval Habitats in Fiyoni, Kwale County, Kenya: Insights into Malaria Vector Ecology and Control
(2023-10-25)The breeding of malaria-spreading vectors such as Anopheles funestus is influenced by various environmental factors that contribute indirectly to the transmission of the Plasmodium parasite. However, there is limited ... -
Antimicrobial Activities of Some Constituents Isolated from a Kenyan Medicinal Plant, Capparis fascicularis DC
(Hindawi, 2023-10-31)Capparis fascicularis DC. is an indigenous medicinal plant belonging to the family Capparaceae found in Nyandarua County, Nairobi, Kenya, and many parts of Africa. It is a shrub whose roots are used traditionally to treat ... -
Plasmodium falciparum Infection Modulates Platelet Count than Leucocyte Parameters in Carriage of Different Haemoglobin Beta Subunit (HBB) Genotypes
(International Knowledge sharing platform, 2023)Sickle cell disease is a prime genetic disorder due to a single nucleotide mutation resulting in haemoglobin gene (HbS) occurring in the regions where malaria is endemic. Though it primarily a disease of erythrocytes, ... -
Substance use disorder and associated factors at an opioid de-addiction clinic in Western Kenya
(Qeios, 2023-07-13)Opioid substitution therapy with methadone is at the heart of substance use disorder intervention at the Jaramogi Oginga Odinga Teaching and Referral Hospital's medication-assisted therapy (MAT) clinic (JOOTRH). However, ... -
Determination of hematological response to iron and folic acid supplementation among the expectant mothers attending Kakamega County Referral Hospital, Kenya
(Medknow, 2023-11-09)Despite iron and folic acid supplementation program among expectant mothers while attending antenatal care clinic at Kakamega County, the rates of maternal and fetal morbidity and mortality due to anemia complications are ... -
Variation in Branching Pattern and Length of Brachial Artery among Black African Population
(International Journal of Innovative Science and Research Technology, 2023-06-06)As the main arterial supply of the upper limb, the normal documented branching pattern of brachial artery is by bifurcation of its terminal branches into radial and ulnar arteries, but due to variations in studies done, ... -
Differences in Demographic Characteristics in the Morphology of Brachial Plexus among Black African Population: A Cadaveric Study in Western Kenya.
(AJOL, 2023-07-07)The anterior principal rami of C5 to C8 and T1 are joined to form brachial plexus (Bp), a network of nerves that wraps around neck and axilla of the body. Trauma, radiation, neoplasms, infections, and autoimmune diseases ... -
Renal Biochemical Marker Changes in Restorative Activities of Curcuma longa on Sildenafil Induced Nephrotoxicity Among Male Albino Rats
(MJBAS, 2023-04-05)Nephrotoxicity is the rapid deterioration of kidney function due to altered histoarchitecture and drug clearance characterized by increased levels of renal biochemical markers. Sildenafil is among the drugs postulated to ... -
Finger print patterns distribution among diabetics and non-diabetics in western Uganda population
(AJOL, 2023-08-17)Dactyloscopy is a branch of dermatoglyphics (the study of epidermal ridges) which involves assessment and classification of fingerprint patterns for identification. All fingerprint patterns are laid down permanently from ... -
Restorative effects of Azadicarachta indica on the kidney histomorphometry in cisplatintreated Wister albino rats
(AJOL, 2023-08-17)Cisplatin is used for treatment of soft tissue tumors and has been associated with nephrotoxicity. Azadirachta indica is a local herb that has been associated with attenuation and counteracting the nephrotoxic effects of ... -
Renal gross morphological restorative effects of Curcuma longa on sildenafil induced nephrotoxicity among male albino rats.
(AJOL, 2023-08-17)Sildenafil is a phosphodiesterase inhibitor used in the management of erectile dysfunction and management of pulmonary hypertension. Curcuma longa is a traditional herbal plant that is commonly used as a diet in Africa and ... -
variations in the origin of the coronary artery in black African population: a cadaveric study in western Kenya
(AJOL, 2023-08-17)The coronary arteries which originate from the right and left aortic orifices are the main blood vessels to the myocardium. Variations are anomalies which could affect the overall perfusion of the myocardium causing ... -
Anatomical variations in morphology of right and left brachial plexus among black African population; a cadaveric study in western Kenya
(AJOL, 2023-08-17)Brachial plexus (Bp) is a network of bundles of nerves of spinal cord around neck and axilla in the body formed by union of anterior primary rami of C5 to C8, and T1. Technical expertise required for clinical and surgical ... -
Age estimation using orthopantomograms and Demirjian method among children attending dental clinics in western Kenya
(AJOL, 2023-10-09)Various methods have been used to estimate age in different populations among them being Demirjian which has widely been utilized. However, in Kenya, there is hardly any approved method that can be used to achieve this ... -
Protective effect of Rosemarinus officinalis on gentamicin-induced acute kidney injury in adult male albino rats
(AJOL, 2023-10-09)Gentamicin (GN) drug is one of the first-line drugs for managing severe gramnegative bacteria. Its association with acute kidney injury (AKI) has restricted its use due to oxidation damage to kidney architectural structures. ... -
Vertebral changes in the lumbar spine of adults presenting with chronic low back pain at a Referral Hospital in western Kenya
(AJOL, 2023-10-09)Chronic low back pain is a common musculoskeletal symptom affecting the lower part of the spine. It is described as pain and discomfort around the lumbar region lasting for more than twelve weeks. The symptoms of chronic ...