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Red blood cell immune complex binding capacity in children with sickle cell trait (HbAS) living in P. falciparum malaria holoendemic region of Western Kenya
(ARMY MEDICAL RESEARCH UNIT-KENYA APO NEW YORK 09675, 2013)
Malaria infection leads to the formation of circulating immune complexes CICs which have been implicated in the pathogenesis of complicated malaria which includes severe malarial anemia. Children with sickle cell trait ...
Dual role of erythrocyte complement receptor type 1 in immune complex‐mediated macrophage stimulation: implications for the pathogenesis of Plasmodium falciparum malaria
(Blackwell Publishing Ltd, 2011)
iven the ability of erythrocytes to bind immune complexes (ICs), we postulated that they can serve a dual role during inflammatory or infectious processes. Erythrocytes could restrict stimulation of macrophages by free ICs ...
The levels of CD16/Fc gamma receptor III A on CD14+CD16+ monocytes are higher in children with severe Plasmodium falciparum anemia than in children with …
(BioMed Central, 2010)
Fc gamma receptor IIIA (CD16/FCgRIIIA) on monocytes/macro-phages may play an important role in the
pathogenesis of severe malarial anemia (SMA) by promoting phagocytosis of IgG-coated uninfected red cells
and by allowing ...
The Benefits of research partnerships to the community at KEMRI/Walter Reed Project
(Dspace, 2015)
Ethical Principles on Human Subject Protection in Clinical Research revolves around Autonomy, Beneficence and Justice. Beneficence requires that the benefits to research participants are maximized as you minimize the risk ...
Sickle cell trait (HbAS) is associated with increased expression of erythrocyte complement regulatory proteins CR1 and CD55 levels in children
(International Journal of TROPICAL DISEASE & Health, 2013)
Aims: Erythrocyte complement regulatory proteins, complement receptor 1 (CR1) and decay accelerating factor (CD55) protect red blood cells (RBCs) from complement mediated damage by controlling complement activation cascade ...
Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia
(BioMed Central, 2010)
Severe anemia due to Plasmodium falciparum malaria is a major cause of mortality among young children in western Kenya. The factors that lead to the age-specific incidence of this anemia are unknown. Previous studies have ...
The levels of CD16/Fc gamma receptor III A on CD14+CD16+ monocytes are higher in children with severe Plasmodium falciparum anemia than in children with …
(BioMed Central, 2010)
Fc gamma receptor IIIA (CD16/FCγRIIIA) on monocytes/macro-phages may play an important role in the pathogenesis of severe malarial anemia (SMA) by promoting phagocytosis of IgG-coated uninfected red cells and by allowing ...
Health care seeking behavior among caregivers of sick children who 2 had severe malarial anaemia 3
(maseno university, 2015)
Aims:
The western region in Kenya is holoendemic to malaria and experience stable P. falciparum malaria
transmission. The use of health care options has a direct influence on the outcome of severe malaria.
As such, the ...
Perspectives of Women on Strategies to Improve the Number of Male Partners Testing for HIV at the Antenatal Clinic in Western Kenya, 2015.
(International Journal of Scientific and Research Publications,, 2015)
- Mother to child transmission of HIV (MTCT) remains
a significant public health problem in Western Kenya. Male
partner testing at the antenatal clinic (ANC) has been cited as a
key strategy to reduce MTCT. The Western ...
, No.20, 2017 1 First-Line Anti-Tuberculosis Drug Susceptibility Patterns of Mycobacterium tuberculosis Complex Strains Responsible for New Cases of Human Pulmonary Tuberculosis in Kisumu County, Western Kenya
(Journal of Natural Sciences Research, 2017)
Background: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, drug-resistant
tuberculosis being a major public health problem. The emergence and spread of multidrug resistant (MDR)
Mycobacterium ...