Browsing School of Medicine by Title
Now showing items 144-163 of 553
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Determination of hematological response to iron and folic acid supplementation among the expectant mothers attending Kakamega County Referral Hospital, Kenya
(Medknow, 2023-11-09)Despite iron and folic acid supplementation program among expectant mothers while attending antenatal care clinic at Kakamega County, the rates of maternal and fetal morbidity and mortality due to anemia complications are ... -
Determination of reference intervals for common chemistry and immunoassay tests for Kenyan adults based on an internationally harmonized protocol and up-to-date statistical methods
(Public Library of Science, 2020-07-09)Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for 40 common chemistry and immunoassay tests as part of the IFCC global RI project. -
Determination of reference intervals for common chemistry and immunoassay tests for Kenyan adults based on an internationally harmonized protocol and up-to-date statistical methods
(Public Library of Science, 2020)Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for 40 common chemistry and immunoassay tests as part of the IFCC global RI project. -
Developing and implementing a pediatric emergency care curriculum for providers at district level hospitals in Sub-Saharan Africa: a case study in Kenya
(Frontiers, 2017)Emergency medicine is a relatively new field in sub-Saharan Africa and dedicated training in pediatric emergency care is limited. While guidelines from the African Federation of Emergency Medicine (AFEM) regarding emergency ... -
Development and initial validation of a pictorial survey to assess for symptomatic pelvic organ prolapse and urinary incontinence in western Kenya
(Springer International Publishing, 2022)Visual tools are a valuable tool for ascertaining patient symptoms, especially in populations with low literacy rates. The objective was to develop and validate a pictorial scale for assessing symptomatic pelvic organ ... -
Diagnostic dose determination and efficacy of chlorfenapyr and clothianidin insecticides against Anopheles malaria vector populations of western Kenya
(BioMed Central, 2019)Background: Malaria vector control is dependent on chemical insecticides applied to walls by indoor residual spraying or on long-lasting insecticidal nets. The emergence and spread of insecticide resistance in major malaria ... -
Differences in Demographic Characteristics in the Morphology of Brachial Plexus among Black African Population: A Cadaveric Study in Western Kenya.
(AJOL, 2023-07-07)The anterior principal rami of C5 to C8 and T1 are joined to form brachial plexus (Bp), a network of nerves that wraps around neck and axilla of the body. Trauma, radiation, neoplasms, infections, and autoimmune diseases ... -
The differential effect of the free maternity services policy in Kenya
(AOSIS Publishing, 2019)BACKGROUND: The Government of Kenya introduced the free maternity services (FMS) policy to enable mothers deliver at a health facility and thus improve maternal health indicators. AIM: The aim of this study was to determine ... -
Differential Gene Expression in Host Ubiquitination Processes in Childhood Malarial Anemia
(Frontiers Media SA, 2021): Malaria remains one of the leading global causes of childhood morbidity and mortality. In holoendemic Plasmodium falciparum transmission regions, such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < ... -
Dihydrofolate reductase I164L mutations in Plasmodium falciparum isolates: clinical outcome of 14 Kenyan adults infected with parasites harbouring the I164L …
(Royal Society of Tropical Medicine and Hygiene, 2008)Recently, Plasmodium falciparum bearing dihydrofolate reductase (DHFR) I164L was isolated from Africa. Quadruple mutations containing I164L confer high-level resistance to antifolate antimalarials. We prospectively measured ... -
Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide
(Nature Publishing Group, 2019-04-17)Bacteremia is a leading cause of death in sub-Saharan Africa where childhood mortality rates are the highest in the world. The early diagnosis of bacteremia and initiation of treatment saves lives, especially in high-disease ... -
Distinct pattern of class and subclass antibodies in immune complexes of children with cerebral malaria and severe malarial anaemia
(Blackwell Publishing Ltd, 2008)Plasmodium falciparum infection can lead to deadly complications such as severe malaria‐associated anaemia (SMA) and cerebral malaria (CM). Children with severe malaria have elevated levels of circulating immune complexes ... -
Distribution and abundance of schistosomiasis and fascioliasis host snails along the Mara River in Kenya and Tanzania
(Taylor & Francis, 2014)We purposively selected 39 sampling sites along the Mara River and its two perennial tributaries of Amala and Nyangores and sampled snails. In addition, water physicochemical parameters (temperature, turbidity, dissolved ... -
Distribution of Biomphalaria Snails in Associated Vegetations and Schistosome Infection Prevalence Along the Shores of Lake Victoria in Mbita, Kenya: A Cross-Sectional Study
(East African Health Research Commission, 2019)Background: Schistosomiasis due to Schistosoma mansoni remains a major public health problem and cause of morbidity and mortality in sub-Saharan Africa despite the implementation of control programmes. More than 6 million ... -
Diversity and taxonomic revision of methanogens and other archaea in the intestinal tract of terrestrial arthropods
(Frontiers, 2023-11-11)Methane emission by terrestrial invertebrates is restricted to millipedes, termites, cockroaches, and scarab beetles. The arthropod-associated archaea known to date belong to the orders Methanobacteriales, Methanomassiliicoccales, ... -
Does cotrimoxazole prophylaxis for the prevention of HIV-associated opportunistic infections select for resistant pathogens in Kenyan adults?
(The American Society of Tropical Medicine and Hygiene, 2008)We assessed the effect of daily cotrimoxazole, essential for HIV care, on development of antifolateresistant Plasmodium falciparum, naso-pharyngeal Streptococcus pneumoniae (pneumococcus), and commensal Escherichia coli. ... -
Dual role of erythrocyte complement receptor type 1 in immune complex‐mediated macrophage stimulation: implications for the pathogenesis of Plasmodium falciparum malaria
(Blackwell Publishing Ltd, 2011)iven the ability of erythrocytes to bind immune complexes (ICs), we postulated that they can serve a dual role during inflammatory or infectious processes. Erythrocytes could restrict stimulation of macrophages by free ICs ... -
Duffy Antigen/Receptor for Chemokines (DARC): Is There a Role in Prostate Cancer?.
(American Society of Hematology, 2005-11-16)Introduction: The Duffy blood group antigens function as chemokine receptors and as receptors for several species of malarial parasites. Approximately 70% of African Americans are Duffy negative as a result of a single ... -
Duffy Antigen/Receptor for Chemokines (DARC): Is There a Role in Prostate Cancer?.
(science direct, 2005)Introduction: The Duffy blood group antigens function as chemokine receptors and as receptors for several species of malarial parasites. Approximately 70% of African Americans are Duffy negative as a result of a single ...