Browsing School of Medicine by Title
Now showing items 127-146 of 553
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Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children
(BioMed Centra, 2017)Background: We aimed to show the non-inferiority of home fortification with a daily dose of 3 mg iron in the form of iron as ferric sodium ethylenediaminetetraacetate (NaFeEDTA) compared with 12.5 mg iron as encapsulated ferrous ... -
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases
(BioMed Central, 2022)Rheumatic heart disease (RHD) remains a major source of morbidity and mortality in developing countries. A deeper insight into the pathogenetic mechanisms underlying RHD could provide opportunities for drug repurposing, ... -
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases
(BioMed Central, 2022)Background Rheumatic heart disease (RHD) remains a major source of morbidity and mortality in developing countries. A deeper insight into the pathogenetic mechanisms underlying RHD could provide opportunities for drug ... -
Defects in resting metabolic rates and mitochondrial respiration in Kwashiorkor and dietary obese rats
(Springer-Verlag, 1991-07-01)Resting metabolic rates have been measured and compared with hepatic mitochondrial respiration in Kwashiorkor and diet-induced obese weaned rats. In Kwashiorkor, resting metabolic rate was 21% lower than the value of ... -
Delay Along the Care Seeking Journey of Patients with Microbial Keratitis in Uganda
(Taylor & Francis, 2019)PURPOSE To describe the care seeking journey and causes of delay among patients with Microbial Keratitis in Uganda. METHODS A prospective cohort of patients presenting with microbial keratitis at the two main eye units ... -
Delayed recovery of adrenocortical and testicular function after chemotherapy of human trypanosomiasis
(Elsevier, 2018)The following indicators of pituitary, adreno-cortical and testicular function were measured in 58 male African trypanosomiasis patients from Western Kenya; plasma cortisol, luteinizing hormone (LH) and testosterone ... -
Depletion of trypanosome CTR9 leads to gene expression defects
(Public Library of Science, 2012-04-20)The Paf complex of Opisthokonts and plants contains at least five subunits: Paf1, Cdc73, Rtf1, Ctr9, and Leo1. Mutations in, or loss of Paf complex subunits have been shown to cause defects in histone modification, mRNA ... -
Deployment of Rotavirus Vaccine in Western Kenya Coincides with a Reduction in All-Cause Child Mortality: A Retrospective Cohort Study
(MDPI, 2023-07-29)Rotavirus is an important cause of fatal pediatric diarrhea worldwide. Many national immunization programs began adding rotavirus vaccine following a 2009 World Health Organization recommendation. Kenya added rotavirus ... -
Design of a novel online, modular, flipped-classroom surgical curriculum for East, Central, and Southern Africa
(LWW, 2022)Objective: We describe a structured approach to developing a standardized curriculum for surgical trainees in East, Central, and Southern Africa (ECSA). Summary Background Data: Surgical education is essential to ... -
Determinants of adherence to anti-retroviral therapy among discordant couples in Usigu Division, Bondo sub-county, Kenya
(Kenya Medical Association, 2018)Objective: To establish the determinants of adherence to ART among discordant couples in Usigu Division, Bondo sub-County. Design: A descriptive cross-sectional study. Setting: Comprehensive Care Clinics within Usigu ... -
Determinants of adherence to tuberculosis chemotherapy in Nairobi City County, Kenya
(East Cent. Afr. J. Pharm. Sci, 2021)Tuberculosis (TB) is a leading global cause of death and Kenya is among the top 20 countries with a high burden of the disease. Adherence to drugs used to treat the disease remains a crucial challenge towards the elimination ... -
Determinants of antibiotic dose adjustment in patients with chronic kidney disease at Kenyatta National Hospital Kenya
(University of Nairobi, 2014)Background: Reduced renal function in chronic kidney disease (CKD) necessitates appropriate dose alterations to avoid drug accumulation. Objectives: The main objective of the study was to determine the prevalence of ... -
Determinants of Appropriate Antibiotic Dosing in Patients with Chronic Kidney Disease in a Kenyan Referral Hospital
(A KeSoBAP Publication, 2014-12-05)Background: Reduced renal function in chronic kidney disease (CKD) necessitates appropriate dose alterations to avoid drug accumulation. Objectives: The main objective of the study was to determine the prevalence of ... -
Determinants of Aquaculture Productivity Among Small Holder Farmers in Bungoma County, Kenya
(Journal of Business, Economics and Management Research Studies, 2023-11-28)The world fish demand is steadily rising as result of low supply thus the need to intensively promote aquaculture. Concerted efforts by the Kenyan government and stakeholders have been in place to promote commercial ... -
Determinants of cadaver acquisition at Human Anatomy Learning Institutions in Kenya
(AJOL, 2023-10-09)Human anatomy instruction in Kenya is based on dissection of cadavers during practical sessions. Institutions get these cadavers using procedures available to them. However, the processes used are not standardized, and ... -
Determinants of quality of life among gynaecological cancer patients on follow up at a referral hospital in Kenya
(University of Nairobi, 2015-06-08)Various factors influence the quality of life (QOL) in cancer patients. This study sought to determine the predictors and factors associated with quality of life among g ynaecological cancer patients on follow up at Kenya ... -
Determinants of Uptake of Intermittent Preventive Treatment for Malaria among Pregnant Women in Suba Sub-County, Homabay County, Kenya
(International Journal of Innovative Research and Development, 2020)Background: Intermittent preventive treatment of malaria in pregnancy (IPTp) is one of the effective and efficacious interventions recommended for prevention of malaria in pregnancy. The drug of choice is Sulphadoxine-Py ... -
Determination of hematological response to iron and folic acid supplementation among the expectant mothers attending Kakamega County Referral Hospital, Kenya
(Medknow, 2023-11-09)Despite iron and folic acid supplementation program among expectant mothers while attending antenatal care clinic at Kakamega County, the rates of maternal and fetal morbidity and mortality due to anemia complications are ... -
Determination of reference intervals for common chemistry and immunoassay tests for Kenyan adults based on an internationally harmonized protocol and up-to-date statistical methods
(Public Library of Science, 2020-07-09)Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for 40 common chemistry and immunoassay tests as part of the IFCC global RI project. -
Determination of reference intervals for common chemistry and immunoassay tests for Kenyan adults based on an internationally harmonized protocol and up-to-date statistical methods
(Public Library of Science, 2020)Due to a lack of reliable reference intervals (RIs) for Kenya, we set out to determine RIs for 40 common chemistry and immunoassay tests as part of the IFCC global RI project.