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Comparison of equations for estimating glomerular filtration rate in screening for chronic kidney disease in asymptomatic black Africans: a cross sectional study

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dc.contributor.author Geoffrey Omuse, Daniel Maina, Jane Mwangi, Caroline Wambua, Alice Kanyua, Elizabeth Kagotho, Angela Amayo, Peter Ojwang, Rajiv Erasmus
dc.date.accessioned 2020-08-18T08:56:28Z
dc.date.available 2020-08-18T08:56:28Z
dc.date.issued 2017-12
dc.identifier.citation 7 en_US
dc.identifier.issn 1471-2369
dc.identifier.uri https://repository.maseno.ac.ke/handle/123456789/2181
dc.description.abstract Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of the equations provide a correction factor for African-Americans due to their relatively increased muscle mass and this has been extrapolated to black Africans. Studies carried out in Africa in patients with CKD suggest that using this correction factor for the black African race may not be appropriate. However, these studies were not carried out in healthy individuals and as such the extrapolation of the findings to an asymptomatic black African population is questionable. We sought to compare the proportion of asymptomatic black Africans reported as having reduced eGFR using various eGFR equations. We further compared the association between known risk factors for CKD with eGFR determined using the different equations. en_US
dc.publisher BioMed Central en_US
dc.subject MDRD;CKD-EPI;Cockcroft-Gault;FAS;eGFR en_US
dc.title Comparison of equations for estimating glomerular filtration rate in screening for chronic kidney disease in asymptomatic black Africans: a cross sectional study en_US
dc.type Article en_US


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