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Safety and immunogenicity of the RTS, S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa
(Elsevier, 2020-01-22)
We assessed the safety and immunogenicity of the RTS,S/AS01 malaria vaccine in a subset of
children identified as HIV-infected during a large phase III randomized controlled trial conducted in
seven sub-Saharan African ...
Safety profile of the RTS, S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa
(Taylor & Francis, 2019-10-03)
A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS,
S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922
children ...
Burden of disease and risk factors for mortality amongst hospitalized newborns in Nigeria and Kenya
(Public Library of Science, 2021-01-14)
Objective To describe the patient population, priority diseases and outcomes in newborns admitted <48 hours old to neonatal units in both Kenya and Nigeria. Study design In a network of seven secondary and tertiary level ...
Estimating annual fluctuations in malaria transmission intensity and in the use of malaria control interventions in five sub-Saharan African countries
(The American Society of Tropical Medicine and Hygiene, 2020-11)
RTS, S/AS01 E malaria vaccine safety, effectiveness, and impact will be assessed in pre-and post-vaccine introduction studies, comparing the occurrence of malaria cases and adverse events in vaccinated versus unvaccinated ...
Estimating Annual Fluctuations in Malaria Transmission Intensity and in the Use of Malaria Control Interventions in Five Sub-Saharan African Countries
(The American Society of Tropical Medicine and Hygiene, 2020)
RTS,S/AS01E malaria vaccine safety, effectiveness, and impact will be assessed in pre- and post-vaccine
introduction studies, comparing the occurrence of malaria cases and adverse events in vaccinated versus unvaccinate ...
Enteral Feeding Practices for Very Preterm and Very Low Birth Weight Infants in Nigeria and Kenya
(Frontiers in pediatrics, 2022-05-11)
Optimizing nutrition in very preterm (28–32 weeks gestation) and very low birth weight (VLBW; 1,000 g to< 1,500 g) infants has potential to improve their survival, growth, and long-term health outcomes.
Aim
To assess ...
Costs of continuing RTS, S/ASO1E malaria vaccination in the three malaria vaccine pilot implementation countries
(Public Library of Science, 2021-01-11)
The RTS,S/ASO1E malaria vaccine is being piloted in three countries—Ghana, Kenya, and Malawi—as part of a coordinated evaluation led by the World Health Organization, with support from global partners. This study estimates ...
Clinical laboratory hematology reference values among infants aged 1month to 17 months in Kombewa Sub-County, Kisumu: A cross sectional study of rural population in Western Kenya
(Public Library of Science, 2021-03-17)
There is an urgent need for reliable region-specific hematological reference values for clinical monitoring. Laboratory reference ranges are important for assessing study participant eligibility, toxicity grading and ...
Assessing the safety, impact and effectiveness of RTS, S/AS01E malaria vaccine following its introduction in three sub-Saharan African countries: methodological approaches and …
(BioMed Central, 2022-12)
Following a 30-year development process, RTS,S/AS01E (GSK, Belgium) is the frst malaria vaccine to
reach Phase IV assessments. The World Health Organization-commissioned Malaria Vaccine Implementation Pro‑
gramme (MVIP) ...
Correction: Costs of continuing RTS, S/ASO1E malaria vaccination in the three malaria vaccine pilot implementation countries
(Public Library of Science, 2021-04-22)
Cost estimates under additional vaccine price assumptions are not included in the main result Table (Table 3). Please view S4 Table,“Unit cost of continuing to vaccinate in pilot areas at various vaccine prices,” for results ...