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Provider knowledge of treatment policy and dosing regimen with artemether-lumefantrine and quinine in malaria-endemic areas of western Kenya
(BioMed Central, 2012-12-29)
Due to widespread anti-malarial drug resistance in many countries, Kenya
included, artemisinin-based Combination Therapy (ACT) has been adopted as the most
effective treatment option against malaria. Artemether-lumefantrine ...
Factors in the management of feeding in nursery school children as perceived by their mothers in rural Bondo County, Kenya
(BioMed Central, 2013-11-15)
The effects of malnutrition on health status and survival of children has been the
subject of extensive research for several decades. Malnutrition affects physical growth,
cognitive development of children, morbidity ...
Polymorphic variability in the 3'untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falc...
(BioMed Central, 2011-08-06)
Plasmodium falciparum malaria remains a leading cause of morbidity and
mortality among African children. Innate immunity provides the first line of defence against P.
falciparum infections, particularly in young children ...
Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating...
(Journals. ASm. org, 2012-10-08)
An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium
falciparum infection would aid in the designing of a rationally based malaria vaccine.
Variants within the Fc gamma receptors ...
Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya
(BioMed Central, 2011-04-20)
The appropriate use of anti-malarial drugs determines therapeutic efficacy and
the emergence and spread of drug-resistant malaria. Strategies for improving drug
compliance require accurate information about current ...
Communicating African spirituality through ecology: Challenges and prospects for the 21st century
(2012-06-19)
This review was set in the context of African spirituality and ecology. Specifically,
the review addressed issues of African spirituality and the environment from a Kenyan
context. Through analyses on existing literature, ...
Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV‐1
(Wiley Subscription Services, Inc., A Wiley Company, 2010-04-01)
Malaria and HIV-1 are coendemic in many developing countries, with anemia being
the most common pediatric hematological manifestation of each disease. Anemia is also
one of the primary causes of mortality in children ...
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)
Development of protective immunity against Plasmodium falciparum is partially mediated
through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human
FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2012)
Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children
residing in regions where plasmodium falciparum transmission is holoendemic. Although
largely unexplored in children with SMA, ...
Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults
(Immunogenetics, 2012)
Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40
subunit is associated with susceptibility to severe malaria in African populations. Since the
role of genetic variation in conditioning ...