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Temporal genetic differentiation in Glossina pallidipes tsetse fly populations in Kenya

Okeyo, Norah P; Mengual, Michael; Dio, Kirstin; Saarman, Norah P; Bateta, Rosemary; Mireji, Paul O; Okoth, Sylvance; Ouma, Johnson O; Ouma, Collins; Ochieng, Joel; Murilla, Grace; Aksoy, Serap; Caccone, Adalgisa (BioMed Central, 2017-12)

Glossina pallidipes is a major vector of both Human and Animal African Trypanosomiasis (HAT and AAT) in Kenya. The disease imposes economic burden on endemic regions in Kenya, including south-western Kenya, which has ...

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya

Munde, Elly O; Okeyo, Winnie A; Raballah, Evans; Anyona, Samuel B; Were, Tom; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BioMed Central, 2017-04-20)

Background Naturally-acquired immunity to Plasmodium falciparum malaria develops after several episodes of infection. Fc gamma receptors (FcγRs) bind to immunoglobulin G (IgG) antibodies and mediate phagocytosis of ...

Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a P. falciparum holoendemic transmission area...

Munde, Elly O; Raballah, Evans; Okeyo, Winnie A; Ong’echa, John M; Perkins, Douglas J; Ouma, Collins (BioMed Central, 2017-04-20)

Background Improved understanding of the molecular mechanisms involved in pediatric severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel therapeutics. Identification of host genetic ...

Multiple evolutionary origins of Trypanosoma evansi in Kenya

Kamidi, Christine M; Saarman, Norah P; Dion, Kirstin; Mireji, Paul O; Ouma, Collins; Murilla, Grace; Aksoy, Serap; Schnaufer, Achim; Caccone, Adalgisa (Public Library of Science, 2017-09-07)

Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world. Trypanosoma evansi transmission can ...

Assessment of community health volunteers’ knowledge on cervical cancer in Kadibo Division, Kisumu County: a cross sectional survey

Ochomo, Edwin O; Atieli, Harrysone; Gumo, Sussy; Ouma, Collins (BioMed Central, 2017-12)

Globally, cervical cancer is the fourth most frequent cancer in women, with an estimated 530,000 new cases in 2012, representing 7.5% of all female cancer deaths. Of the estimated more than 270,000 deaths from cervical ...

HAPLOTYPES WITHIN NFKBIA PROMOTER ARE ASSOCIATED WITH SEVERE MALARIAL ANEMIA AND CIRCULATING IL-10 AND IP-10 LEVELS IN CHILDREN...

Munde, Elly O; Achieng, Angela O; Kisia, Lily E; Karim, Zachery S; Raballah, Evans O; Kempaiah, Prakasha; Ong'echa, John M; Ouma, Collins; Perkins, Douglas J (AMER SOC TROP MED & HYGIENE, 2017-11-01)

HAPLOTYPES WITHIN NFKBIA PROMOTER ARE ASSOCIATED WITH SEVERE MALARIAL ANEMIA AND CIRCULATING IL-10 AND IP-10 LEVELS IN CHILDREN WITH PLASMODIUM FALCIPARUM MALARIA

MYCOBACTERIUM TUBERCULOSIS RESISTANCE TO ISONIAZID AND RIFAMPICIN IN A HIV-1 ENDEMIC POPULATION IN WESTERN KENYA IN 2014

Likhovole, Clement; Ouma, Collins; Vulule, John; Musau, Susan; Khayumbi, Jeremiah; Okumu, Albert; Murithi, Wilfred (BMJ Specialist Journals, 2017-02-01)

Background The spread of mono-resistant and multi-drug resistant tuberculosis (MDR-TB) has been enhanced by delays in the identification of resistant strains. However, resistance gene patterns and the extent and ...