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    Multiple evolutionary origins of Trypanosoma evansi in Kenya

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    Publication Date
    2017-09-07
    Author
    Kamidi, Christine M
    Saarman, Norah P
    Dion, Kirstin
    Mireji, Paul O
    Ouma, Collins
    Murilla, Grace
    Aksoy, Serap
    Schnaufer, Achim
    Caccone, Adalgisa
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    Abstract/Overview
    Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world. Trypanosoma evansi transmission can be sustained mechanically by tabanid and Stomoxys biting flies, whereas the closely related African trypanosomes T. brucei brucei and T. b. rhodesiense require cyclical development in tsetse flies (genus Glossina) for transmission. In this study, we investigated the evolutionary origins of T. evansi. We used 15 polymorphic microsatellites to quantify levels and patterns of genetic diversity among 41 T. evansi isolates and 66 isolates of T. b. brucei (n= 51) and T. b. rhodesiense (n= 15), including many from Kenya, a region where T. evansi may have evolved from T. brucei. We found that T. evansi strains belong to at least two distinct T. brucei genetic units and …
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    https://repository.maseno.ac.ke/handle/123456789/153
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