Browsing Biomedical Science by Title
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Antibody Responses to Plasmodium Falciparum Antigens in Hiv Infected Adults in Bondo Sub County Hospital, Siaya County, Kenya
(Maseno University, 2016)Malaria and human immunodeficiency virus (HIV) are co-endemic in sub-Saharan Africa. Infection with HIV results in B cell anomalies. Antibodies are critical in protection against malaria and it is hypothesized that B cell ... -
Antimicrobial Activities of Secondary Metabolites From Vernonia Adoensis and Ocimum Kilimandscharicum Medicinal Plants and Associated Endophytes From Kakamega Forest in Kenya
(Maseno University, 2016)Medicinal plants have been used for the treatment of different ailments in human and animal health systems for many years. Approximately over 80% of rural and urban African populations use plant-based synthetic products ... -
Association between genetic variations in selected cell receptors and nuclear transcription factors and susceptibility to Paediatric p. Falciparum severe malaria Anaemia in Siaya county, Western Kenya
(Maseno University, 2018)ABSTRACT Plasmodium falciparum severe malaria aneamia [SMA, haemoglobin (Hb) <5.0 g/dL or Hb<6.0 g/dL with any parasite density] remains the most life-threatening malaria. With its immuno-genetic basis partially understood, ... -
Association between Ifn-γ, Tnf-α, Fcγriia and il-12β gene Polymorphisms and Susceptibility to Endemic Burkitt Lymphoma in children from Western Kenya
(Maseno University, 2018)Endemic Burkitt lymphoma (eBL) is an aggressive paediatric B-cell lymphoma prevalent in children from holoendemic malaria regions of sub-Saharan Africa. It is associated with early primary Epstein-Barr virus (EBV) and ... -
Associations between Functional Variations in Fc'yriiia and TLR 9 and Susceptibility to Severe Malaria Anemia in Cidldren below 3 Years in Western Kenya
(Maseno University, 2013)Plasmodium Jalciparum malaria in holoendemic transmission areas is a major cause of childhood morbidity and mortality. The greatest burden of this morbidity and mortality is as a consequence of severe malaria anemia (SMA) ... -
Characterization and source tracking of diarrheagenic bacteria contaminating fish in lake victoria, Kenya
(Maseno University, 2016)Lake Victoria is an important source of fish. Nonetheless, fish has been reported to be of low microbiological quality as they have been reported to be contaminated with Escherichia coli, Vibrio spp, Shigella spp and ... -
Clinical equivalence of heparinized arterial plasma to venous Serum for magnesium and phosphate measurement among Patients admitted at the intensive care unit of Moi teaching and referral hospital
(Maseno University, 2018)Electrolytes routinely measured in patients in Intensive Care Unit (ICU) are sodium, potassium, chloride, calcium, magnesium and phosphate. Of these; sodium, potassium, chloride and calcium are measured as part of tests ... -
Comparison of diagnostic performance of mini-flotac with formalin-ether concentration and kato-katz for detection of intestinal helminths and protozoa in nursery school children in Mbita, Western Kenya
(Maseno University, 2016)Schistosoma mansoni (S. mansoni), soil-transmitted helminths (STH) and protozoa affect approximately 2 billion people world-wide. Most of these infections occur in developing countries and children below 14 years of age ... -
Comparison of hepatitis B virus sero-markers, clinical stages and genotypes between HIV-1 infected and uninfected injecting substance users in Mombasa city, Kenya
(Maseno University, 2015)Globally, it is estimated that 1.2 million injecting substance users are HBV infected while 1.7 million live with HIV. Africa is home to about 1.02 million injecting substance users of whom 12.7% are HBV infected while ... -
Comparison of perfomance and factors that affect circulating cathodic antigen, kato-katz and elisa tests for schistosoma mansoni diagnosis in school children in Western Kenya
(Maseno University, 2015)Schistosomiasis infects approximately 207 million people worldwide with 90% of the cases occurring in Africa. Kato-Katz, is the standard method of S.mansoni diagnosis, however it is characterized by low sensitivity. Another ... -
Development of antibody dependent respiratory burst assay as a tool for evaluating cellular immunity to malaria
(Maseno University, 2016)Malaria vaccine clinical trials in exposed populations have not always been consistent in finding robust associations between the predicted immune responses and protection against disease. The selection of most promising ... -
The diagnostic accuracy, sensitivity and specificity of fine needle aspiration cytology in evaluating thyroid masses at Moi teaching and referral hospital
(2016)Thyroid masses are common surgical presentations with a worldwide prevalence of 4–7% in the general adult population. Africa, specifically Kenya is not excluded from these surgical conditions. The vast majority of adult ... -
Effect of knockdown resistance on plasmodium falciparum sporozoite rates in malaria vectors in western Kenya
(Maseno University, 2017) -
Effect of maternal plasmodium falciparum malaria infection during pregnancy on trans-placental transfer of Epstein Barr virus-specific igG antibodies, fetal lymphocyte homeostasis and cytokines in Chulaimbo
(Maseno University, 2015)Co-infection with malaria and Epstein Barr virus (EBV) have been implicated in the etiology of endemic Burkitt’s lymphoma (eBL) but the precise mechanism by which these two agents lead to the pathogenesis of eBL has been ... -
Efficacy of Chlorfenapyr and Clothianidin Insecticides on Anopheles Malaria Vector populations of Nyando, Bumula and Ndhiwa sub-counties, Western Kenya
(Maseno University, 2018)Malaria is a global health problem resulting in 435,000 deaths annually with 90% of the deaths occurring in sub-Saharan Africa. Over 70% of the Kenyan population is at risk of malaria and western Kenya is an endemic region ... -
An evaluation of Bacteriological quality of Water from ready-to-eat food outlets in Maseno Township, Western Kenya
(Maseno University, 2016)Water is a commodity which is essential for life as it has long been singled out globally as the most important factor in sustaining human health. Among other factors linked to human health; water has been implicated in ... -
Evaluation of the performance of Sacace HPV genotypes 14 real-tm quant and Carehpv against linear array in detection of human Papilloma virus genotypes in women from Western Kenya
(Maseno University, 2018)Cervical cancer (CC) is common among women, with global estimates of over 530,000 new cases and over 270,000 deaths annually. Human papilloma virus (HPV) infection increases the risk for CC development while high HIV ... -
Evaluation of the Repellency Effectiveness of Linalool and Metofluthrin against Anopheles Gambiae S.L. in Kisian Village, Western Kenya
(Maseno University, 2012)Malaria continues to pose a major public health threat. Despite the efforts that have been made to prevent humans from mosquito bites, changes in the vector biting behavior, and mosquitoes tending to bite earlier before ... -
Expression of cd23 by schistosoma mansoni antigen-activated b cells of highly exposed adult males on the shores of lake Victoria, Western Kenya
(Maseno University, 2016)Increased B cell membrane CD23 (low affinity IgE receptor) and its soluble cleavage product (sCD23) is related to the development of resistance to re-infection with Schistosoma mansoni. CD23 occurs as two isoforms (CD23a ...