| dc.contributor.author | S RTS, Elisha Adeniji, Kwaku Poku Asante, Owusu Boahen, Guillaume Compaoré, Boubacar Coulibaly, Seyram Kaali, Youssouf Kabore, Mathieu Lamy, John Lusingu, Anangisye Malabeja, Petra Mens, Mattéa Orsini, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Janet Oyieko, Jean-Yves Pirçon, Nicolas Praet, François Roman, Ali Sie, Valentine Sing’oei, Sodiomon B Sirima, Khadime Sylla, Roger Tine, Alfred B Tiono, Mathilda Tivura, Effua Usuf, Stéphanie Wéry | |
| dc.description.abstract | RTS, S/AS01 E malaria vaccine safety, effectiveness, and impact will be assessed in pre-and post-vaccine introduction studies, comparing the occurrence of malaria cases and adverse events in vaccinated versus unvaccinated children. Because those comparisons may be confounded by potential year-to-year fluctuations in malaria transmission intensity and malaria control intervention usage, the latter should be carefully monitored to adequately adjust the analyses. This observational cross-sectional study is assessing Plasmodium falciparum parasite prevalence (PfPR) and malaria control intervention usage over nine annual surveys performed at peak parasite transmission. Plasmodium falciparum parasite prevalence was measured by microscopy and nucleic acid amplification test (quantitative PCR) in parallel in all participants, and defined as the proportion of infected participants among participants tested … | en_US |
