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Seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya

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dc.contributor.author Onyango, Calleb G
dc.contributor.author Ogonda, Lilian
dc.contributor.author Guyah, Bernard
dc.contributor.author Okoth, Peter
dc.contributor.author Shiluli, Clement
dc.contributor.author Humwa, Felix
dc.contributor.author Opollo, Vallarie
dc.date.accessioned 2018-05-09T12:53:30Z
dc.date.available 2018-05-09T12:53:30Z
dc.date.issued 2018-03-12
dc.identifier.other https://doi.org/10.1186/s13104-018-3276-y
dc.identifier.uri https://repository.maseno.ac.ke/handle/123456789/510
dc.description.abstract Since the implementation of a series of blood donation safety improvements in Kenya, information about seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors especially in high HIV burden regions of Homabay, Kisumu and Siaya counties remain scanty. A cross-sectional study examining HIV, syphilis, hepatitis B and C virus sero-markers and associated determinants was conducted among voluntary blood donors. Their demographic characteristics and previous risk exposure were recorded in a pre-donation questionnaire, while blood samples collected were screened for hepatitis B, hepatitis C, human immunodeficiency viruses by ELISA and RPR (syphilis), then confirmed using CMIA. Overall TTIs seroprevalence was 114 (9.4%), distributed among HIV, HBV, HCV and syphilis at 14 (1.15%), 42 (3.46%), 39 (3.21%) and 19 (1.56%), respectively, with co-infections of 3 (0.25%). There were no significant differences in proportions distributions among demographic variables. However, high risk sex was significantly associated with higher odds of HBV infections [> 1 partner vs. 0–1 partner; odd ratio (OR) 2.60; 95% confidence interval (CI) 1.098–6.86; p = 0.046]. In conclusion, a substantial percentage of blood donors still harbor transfusion transmissible infections despite recent safety improvements with greater majority cases caused by HBV infections arising from previous exposure to high risk sex. en_US
dc.publisher BioMed Central en_US
dc.subject Seroprevalence, HIV, HBV, Donors, Kenya en_US
dc.title Seroprevalence and determinants of transfusion transmissible infections among voluntary blood donors in Homabay, Kisumu and Siaya counties in western Kenya en_US
dc.type Article en_US


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