Paediatrics and Child Health: Recent submissions
Now showing items 21-39 of 39
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Baseline incidence of meningitis, malaria, mortality and other health outcomes in infants and young sub-Saharan African children prior to the introduction of the RTS, S/AS01E …
(BioMed Central, 2021-04-26)The lack of background disease incidence rates in sub-Saharan countries where the RTS,S/AS01E malaria vaccine is being implemented may hamper the assessment of vaccine safety and effectiveness. This study aimed to document ... -
Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya
(BioMed Central, 2021-12)In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ... -
Caffeine for the care of preterm infants in sub-Saharan Africa: a missed opportunity?
(BMJ Specialist Journals, 2021-12-01)In 2019, 2.4 million neonates (infants< 28 days of age) died globally. Of these, over 80% were preterm infants (< 37 weeks gestation), with the majority born in low-income and middle-income countries. 1 Complications of ... -
Enteral Feeding Practices for Very Preterm and Very Low Birth Weight Infants in Nigeria and Kenya
(Frontiers in pediatrics, 2022-05-11)Optimizing nutrition in very preterm (28–32 weeks gestation) and very low birth weight (VLBW; 1,000 g to< 1,500 g) infants has potential to improve their survival, growth, and long-term health outcomes. Aim To assess ... -
Assessing the safety, impact and effectiveness of RTS, S/AS01E malaria vaccine following its introduction in three sub-Saharan African countries: methodological approaches and …
(BioMed Central, 2022-12)Following a 30-year development process, RTS,S/AS01E (GSK, Belgium) is the frst malaria vaccine to reach Phase IV assessments. The World Health Organization-commissioned Malaria Vaccine Implementation Pro‑ gramme (MVIP) ... -
The paediatrician workforce and its role in addressing neonatal, child and adolescent healthcare in Kenya
(BMJ, 2020)To examine the availability of paediatricians in Kenya and plans for their development. -
Clinical cascades as a novel way to assess physical readiness of facilities for the care of small and sick neonates in Kenya and Uganda
(PLOS, 2018)Background Globally, there were 2.7 million neonatal deaths in 2015. Significant mortality reduction could be achieved by improving care in low- and middle-income countries (LMIC), where the majority of deaths occur. ... -
Factors influencing mothers’ decisions regarding obstetrical care in Western Kenya: a mixed-methods study
(BioMed Central, 2021)Siaya County in Western Kenya has one of the highest maternal mortality rates in Kenya. We sought to elucidate factors that influence mothers’ decisions regarding where to seek obstetrical care, to inform interventions ... -
Caffeine for the care of preterm infants in sub-Saharan Africa: a missed opportunity?
(BMJ Specialist Journals, 2021)In 2019, 2.4million neonates (infants <28 days of age) died globally. Of these, over 80% were preterm infants (<37 weeks gestation), with the majority born in low-income and middle-income countries.1 Complications ... -
Risk factors for hypertension among young adults (18-35) years attending in Tenwek Mission Hospital, Bomet County, Kenya in 2018
(The pan African medical journal, 2019)hypertension ranks third in the world, after underweight and unsafe sex, in the list of six major risk factors contributing to the global disease. In Kenya, the prevalence stands at 24% in the general population, while ... -
Immunophenotypic Characterization of ART- naive, HIV Infected Adults in Kombewa Sub-county, Kisumu: A Cross Sectional Study of Rural Population in Western Kenya
(Journal of Clinical Immunology and Research, 2020)Reliable information on clinical immunophenotypic biomarkers is critical in the management of Hepatitis B and C infections especially in ART naive HIV positive adults. CD4 cell counts and the level of liver function ... -
Case Report: An unusual case of bee envenomation presenting with acute kidney injury, cavernous venous thrombosis and multiple episodes of convulsions
(peertechzpublications, 2020)Bee stings are common in the tropics and cause minor problems but may occasionally cause severe anaphylactoid reactions -
Baseline incidence of meningitis, malaria, mortality and other health outcomes in infants and young sub-Saharan African children prior to the introduction of the RTS,S/AS01E malaria vaccine
(BioMed Central, 2021)The lack of background disease incidence rates in sub-Saharan countries where the RTS,S/AS01E malaria vaccine is being implemented may hamper the assessment of vaccine safety and efectiveness. This study aimed to document ... -
Differential Gene Expression in Host Ubiquitination Processes in Childhood Malarial Anemia
(Frontiers Media SA, 2021): Malaria remains one of the leading global causes of childhood morbidity and mortality. In holoendemic Plasmodium falciparum transmission regions, such as western Kenya, severe malarial anemia [SMA, hemoglobin (Hb) < ... -
Burden of disease and risk factors for mortality amongst hospitalized newborns in Nigeria and Kenya
(Public Library of Science, 2021-01-14)To describe the patient population, priority diseases and outcomes in newborns admitted <48 hours old to neonatal units in both Kenya and Nigeria. -
Case report: Acute Kidney Injury, Liver impairment, Severe Anemia in a child with Malaria and Hyperparasitaemia
(Global journal of medical and clinical case reports, 2021-01-19)Severe Malaria is a medical emergency mainly because of its rapid progression to complications and death if not promptly and adequately treated. In 2018 WHO put the incidence of P. falciparum Malaria in the African region ... -
Clinical laboratory hematology reference values among infants aged 1month to 17 months in Kombewa Sub-County, Kisumu: A cross sectional study of rural population in Western Kenya
(Public Library of Science, 2021-03-17)There is an urgent need for reliable region-specific hematological reference values for clinical monitoring. Laboratory reference ranges are important for assessing study participant eligibility, toxicity grading and ... -
Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya
(Springer, 2021)In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ... -
Caffeine for the care of preterm infants in sub- Saharan Africa: a missed opportunity?
(BMJ Specialist Journals, 2021)In 2019, 2.4 million neonates (infants <28 days of age) died globally. Of these, over 80% were preterm infants (<37 weeks gestation), with the majority born in low- income and middle- income countries.1 Complications of ...