Browsing Paediatrics and Child Health by Title

Now showing items 27-38 of 38

    • A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa 

      Sandra Van Puyvelde, Tessa De Block, Sushmita Sridhar, Matt Bawn, Robert A Kingsley, Brecht Ingelbeen, Mathew A Beale, Barbara Barbé, Hyon Jin Jeon, Lisette Mbuyi-Kalonji, Marie-France Phoba, Dadi Falay, Delphine Martiny, Olivier Vandenberg, Dissou Affolabi, Jean Pierre Rutanga, Pieter-Jan Ceyssens, Wesley Mattheus, Wim L Cuypers, Marianne AB Van Der Sande, Se Eun Park, Simon Kariuki, Kephas Otieno, John PA Lusingu, Joyce R Mbwana, Samuel Adjei, Anima Sarfo, Seth O Agyei, Kwaku P Asante, Walter Otieno, Lucas Otieno, Marc C Tahita, Palpouguini Lompo, Irving F Hoffman, Tisungane Mvalo, Chisomo Msefula, Fatimah Hassan-Hanga, Stephen Obaro, Grant Mackenzie, Stijn Deborggraeve, Nicholas Feasey, Florian Marks, Calman A MacLennan, Nicholas R Thomson, Jan Jacobs, Gordon Dougan, Samuel Kariuki, Octavie Lunguya (Nature Publishing Group UK, 2023-10-23)
      Invasive non-typhoidal Salmonella (iNTS) disease manifesting as bloodstream infection with high mortality is responsible for a huge public health burden in sub-Saharan Africa. Salmonella enterica serovar Typhimurium (S. ...

    • Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya 

      Paul Kosiyo, Walter Otieno, Jesse Gitaka, Elly O. Munde & Collins Ouma (Springer, 2021)
      In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ...

    • Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya 

      Paul Kosiyo, Walter Otieno, Jesse Gitaka, Elly O Munde, Collins Ouma (BioMed Central, 2021-12)
      In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ...

    • Immunophenotypic Characterization of ART- naive, HIV Infected Adults in Kombewa Sub-county, Kisumu: A Cross Sectional Study of Rural Population in Western Kenya 

      Ochola, Jew; Korir, Jackson C.; Otieno, Walter; Ake, Julie; Polyak, Christina; Mulama, David H. (Journal of Clinical Immunology and Research, 2020)
      Reliable information on clinical immunophenotypic biomarkers is critical in the management of Hepatitis B and C infections especially in ART naive HIV positive adults. CD4 cell counts and the level of liver function ...

    • Immunophenotypic Characterization of ART-naive, HIV Infected Adults in Kombewa Sub-county, Kisumu: A Cross Sectional Study of Rural Population in Western Kenya 

      Jew Ochola, Jackson C Korir, Walter Otieno, Julie Ake, Christina Polyak, David H Mulama (Journal of Clinical Immunology and Research, 2020-11-12)
      Reliable information on clinical immunophenotypic biomarkers is critical in the management of Hepatitis B and C infections especially in ART naive HIV positive adults. CD4 cell counts and the level of liver function ...

    • The paediatrician workforce and its role in addressing neonatal, child and adolescent healthcare in Kenya 

      Mike English, , Brigid Strachan, Fabian Esamai, Thomas Ngwiri,5 Osman Warfa,6 Patrick Mburugu,7 Grace Nalwa,8 Jesse Gitaka,9 John Ngugi, Yingxi Zhao , Paul Ouma, Fred Were (BMJ, 2020)
      To examine the availability of paediatricians in Kenya and plans for their development.

    • Prostration and the prognosis of death in African children with severe malaria 

      Selidji T Agnandji, Mario Recker, Benjamin Mordmüller, Stephan Glöckner, Akim A Adegnika, Bertrand Lell, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Kwaku P Asante, Tsiri Agbenyega, Daniel Ansong, Eusebio Macete, Pedro Aide, Hermann Sorgho, Halidou Tinto, Neema Mturi, John PA Lusingu, Samwel Gesase, Irving Hoffman, Nahya Salim Masoud, Charles R Newton, Kalifa Bojang, Gérard Krause, Peter Gottfried Kremsner (Elsevier, 2023-09-01)
      Malaria is still one of the main reasons for hospitalization in children living in sub-Saharan Africa. Rapid risk stratification at admission is essential for optimal medical care and improved prognosis. Whereas coma, deep ...

    • Risk factors for hypertension among young adults (18-35) years attending in Tenwek Mission Hospital, Bomet County, Kenya in 2018 

      Damaris Ogake Ondimu1, &, Gideon Mutie Kikuvi1 , Walter None Otieno2 (The pan African medical journal, 2019)
      hypertension ranks third in the world, after underweight and unsafe sex, in the list of six major risk factors contributing to the global disease. In Kenya, the prevalence stands at 24% in the general population, while ...

    • Safety and immunogenicity of the RTS, S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa 

      Lucas Otieno, Yolanda Guerra Mendoza, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Simon Kariuki, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, Marc Lievens, John Lusingu, Anangisye Malabeja, Nahya Salim Masoud, Ali Takadir Mtoro, Patricia Njuguna, Opokua Ofori-Anyinam, Godfrey Allan Otieno, Walter Otieno, Seth Owusu-Agyei, Lode Schuerman, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Pascale Vandoolaeghe, Jahit Sacarlal, Martina Oneko (Elsevier, 2020-01-22)
      We assessed the safety and immunogenicity of the RTS,S/AS01 malaria vaccine in a subset of children identified as HIV-infected during a large phase III randomized controlled trial conducted in seven sub-Saharan African ...

    • Safety profile of the RTS, S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa 

      Yolanda Guerra Mendoza, Elodie Garric, Amanda Leach, Marc Lievens, Opokua Ofori-Anyinam, Jean-Yves Pirçon, Jens-Ulrich Stegmann, Pascale Vandoolaeghe, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Jahit Sacarlal, Nahya Salim Masoud, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Ali Takadir Mtoro, Patricia Njuguna, Martina Oneko, Godfrey Allan Otieno, Kephas Otieno, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, John Lusingu, Anangisye Malabeja, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Lode Schuerman (Taylor & Francis, 2019-10-03)
      A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS, S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children ...

    • Time to full enteral feeds in hospitalised preterm and very low birth weight infants in Nigeria and Kenya 

      Zainab O Imam, Helen M Nabwera, Olukemi O Tongo, Pauline EA Andang’o, Isa Abdulkadir, Chinyere V Ezeaka, Beatrice N Ezenwa, Iretiola B Fajolu, Martha K Mwangome, Dominic D Umoru, Abimbola E Akindolire, Walter Otieno, Macrine Olwala, Grace M Nalwa, Alison W Talbert, Ismaela Abubakar, Nicholas D Embleton, Stephen J Allen, Neonatal Nutrition Network (NeoNuNet) (Public Library of Science, 2024-03-08)
      Preterm (born < 37 weeks’ gestation) and very low birthweight (VLBW; <1.5kg) infants are at the greatest risk of morbidity and mortality within the first 28 days of life. Establishing full enteral feeds is a vital aspect ...

    • The Walter Reed Project, Kisumu Field Station: Impact of Research on Malaria Policy, Management, and Prevention. 

      Peter M Sifuna, Michal Mbinji, Tina O Lucas, Irene Onyango, Hoseah M Akala, John N Waitumbi, Bernhards R Ogutu, Jack N Hutter, Walter Otieno (The American Journal of Tropical Medicine and Hygiene, 2024-04-23)
      The Walter Reed Project is a collaboration between the Walter Reed Army Institute of Research of the United States Department of Defense and the Kenya Medical Research Institute. The Kisumu field station, comprising four ...