• Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study) 

      Liesl Zühlke, Mark E Engel, Ganesan Karthikeyan, Sumathy Rangarajan, Pam Mackie, Blanche Cupido, Katya Mauff, Shofiqul Islam, Alexia Joachim, Rezeen Daniels, Veronica Francis, Stephen Ogendo, Bernard Gitura, Charles Mondo, Emmy Okello, Peter Lwabi, Mohammed M Al-Kebsi, Christopher Hugo-Hamman, Sahar S Sheta, Abraham Haileamlak, Wandimu Daniel, Dejuma Y Goshu, Senbeta G Abdissa, Araya G Desta, Bekele A Shasho, Dufera M Begna, Ahmed ElSayed, Ahmed S Ibrahim, John Musuku, Fidelia Bode-Thomas, Basil N Okeahialam, Olukemi Ige, Christopher Sutton, Rajeev Misra, Azza Abul Fadl, Neil Kennedy, Albertino Damasceno, Mahmoud Sani, Okechukwu S Ogah, Taiwo Olunuga, Huda HM Elhassan, Ana Olga Mocumbi, Abiodun M Adeoye, Phindile Mntla, Dike Ojji, Joseph Mucumbitsi, Koon Teo, Salim Yusuf, Bongani M Mayosi (Oxford University Press, 2015)
      This prospective registry enrolled 3343 patients (median age 28 years, 66.2% female) presenting with RHD at 25 hospitals in 12 African countries, India, and Yemen between January 2010 and November 2012. The majority (63.9%) ...
    • Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases 

      M Taariq Salie, Jing Yang, Carlos R Ramírez Medina, Liesl J Zühlke, Chishala Chishala, Mpiko Ntsekhe, Bernard Gitura, Stephen Ogendo, Emmy Okello, Peter Lwabi, John Musuku, Agnes Mtaja, Christopher Hugo-Hamman, Ahmed El-Sayed, Albertino Damasceno, Ana Mocumbi, Fidelia Bode-Thomas, Christopher Yilgwan, Ganiyu A Amusa, Esin Nkereuwem, Gasnat Shaboodien, Rachael Da Silva, Dave Chi Hoo Lee, Simon Frain, Nophar Geifman, Anthony D Whetton, Bernard Keavney, Mark E Engel (BioMed Central, 2022)
      Rheumatic heart disease (RHD) remains a major source of morbidity and mortality in developing countries. A deeper insight into the pathogenetic mechanisms underlying RHD could provide opportunities for drug repurposing, ...
    • Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases 

      M Taariq Salie, Jing Yang, Carlos R Ramírez Medina, Liesl J Zühlke, Chishala Chishala, Mpiko Ntsekhe, Bernard Gitura, Stephen Ogendo, Emmy Okello, Peter Lwabi, John Musuku, Agnes Mtaja, Christopher Hugo-Hamman, Ahmed El-Sayed, Albertino Damasceno, Ana Mocumbi, Fidelia Bode-Thomas, Christopher Yilgwan, Ganiyu A Amusa, Esin Nkereuwem, Gasnat Shaboodien, Rachael Da Silva, Dave Chi Hoo Lee, Simon Frain, Nophar Geifman, Anthony D Whetton, Bernard Keavney, Mark E Engel (BioMed Central, 2022)
      Background Rheumatic heart disease (RHD) remains a major source of morbidity and mortality in developing countries. A deeper insight into the pathogenetic mechanisms underlying RHD could provide opportunities for drug ...
    • Design of a novel online, modular, flipped-classroom surgical curriculum for East, Central, and Southern Africa 

      Andrea S Parker, Katherine A Hill, Bruce C Steffes, Deirdre Mangaoang, Eric O’Flynn, Niraj Bachheta, Maria F Bates, Caesar Bitta, Nicholas H Carter, Richard E Davis, Jeremy A Dressler, Deborah A Eisenhut, Akinniyi E Fadipe, John K Kanyi, Rondi M Kauffmann, Frances Kazal, Patrick Kyamanywa, Justus O Lando, Heath R Many, Valentine C Mbithi, Amanda J McCoy, Peter C Meade, Wairimu YB Ndegwa, Emmy A Nkusi, Philip B Ooko, Dixon JS Osilli, Madison ED Parker, Sinkeet Rankeeti, Katherine Shafer, James D Smith, David Snyder, Kimutai R Sylvester, Michelle E Wakeley, Marvin K Wekesa, Laura Torbeck, Russell E White, Abebe Bekele, Robert K Parker (LWW, 2022)
      Objective: We describe a structured approach to developing a standardized curriculum for surgical trainees in East, Central, and Southern Africa (ECSA). Summary Background Data: Surgical education is essential to ...
    • Enhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial 

      Bruce M Biccard, Leon du Toit, Maia Lesosky, Tim Stephens, Landon Myer, Agya BA Prempeh, Nicola Vickery, Hyla-Louise Kluyts, Alexandra Torborg, Akinyinka Omigbodun, Adesoji Ademuyiwa, Muhammed Elhadi, Mohamed Elfagieh, Bernard Mbwele, Mpoki Ulisubisya, Lazaro Mboma, Daniel Z Ashebir, Mahlet Tesfaye Bahta, Mohammed Hassen, Mikiyas Teferi, Yakob Seman, Eugene Zoumenou, Adam Hewitt-Smith, Janat Tumukunde, Dolly Munlemvo, Atilio Morais, Apollo Basenero, Pisirai Ndarukwa, Nazinigouba Ouerdraogo, Maman Sani Chaibou, Mohyeddine Zarouf, Ahmed Rhassane El Adib, Veekash Gobin, Zimogo Sanogo, Youssouf Coulibaly, Zipporah Ngumi, Tarig Fadalla, Cynthia Iradukunda, Vénérand Barendegere, Isaac O Smalle, Mustapha Bittaye, Ahmadou Lamin Samateh, Mahmoud Elfiky, Maher Fawzy, Wakisa Mulwafu, Vanessa Msosa, Lygia Lopes, Akwasi Antwi-Kusi, Hamza D Sama, Patrice Forget, Dawid van Straaten, Rupert M Pearse, Marichen Puchert, Lucy Rolt, Kris Schwebler, Freddy Kabambi, Tebogo Mabotja, Leandys Cobas, Albino Freitas, Maria Antunes, Bartolomeu Cabo, Domingos Paulo, Carlos Camongua, Yvette Avognon, Osseni Marcos, Raymond Kintomonho, Onesime Demahou, Gisèle Hounsa, Hugues Chobli, Elie Fassinou, Aurore Zoglobossou, Blaise Tchaou, Charles Tchegnonsi, Fifame Amadji, Francine Bossa, Ernest Ahounou, Djima Alao, Roushdane Odérémi, Afissatou Montairou, Oswald Gbehade, Romaric Tobome, Adam Boukari, Patrick Bakantieba, Arouna Sambo, Fanou Lionelle, Nounagnon Gilbert, Julien Attinon, Roger Klikpezo, Aumar Dadjo, Dénis Fanou, Gilberte Hounkpe, Bachabi Fafana, Néné Nguilu, Bodourin Dossou-Yovo, Chantal Segla, Mohamed Toko, Evelyne Gnele-Dedewanou, Michel Noukounwoui, Ethienne Yado, Timothé Gouroubéra, Valéry Adjignon, Serge Mewanou, Aïcha Tchomgang, Urielle Agossou, Fernand Soton, Charbel Azanlin, Lidwine Zomahoun, Rawéléguinbasba Armel Flavien Kabore, Salam Savadogo, Fatou Fleur Rosine Sanou, Farid Belém, Victoria Hien, Cheik Tidiane Hafid W Bougouma, Sie Ahmed Ouattara, Mariam Bambara Kabore, Ouedraogo Nazinigouba, Papougnezambo Bonkoungou, Martin Lankoandé, Mireille Traoré, Patrick Sawadogo, Inès Wenmenga, Boureima Kinda, André Simporé, Christian Sapo, Salah Idriss Traore, Haoua Dipama, Lydie WR Kaboré, Salifou Napon, Télesphore G Kaboré, Arouna Louré, Pélagie PP Tondé, Christian Zoundi, Harouna Sanou, Remy Ndikumana, Carlos Nsengiyumva, Gregory Sund, Alliance Niyukuri, Axel Kwizera, Jean-Claude Niyondiko, Adolphe Manzanza Kilembe, Jean Pierre Mwema Ilunga, Nehema Hailemariam Sarah, Gabriel Mubobo Makeya, Idesbald Mwebe Mwepu, Ted Botawaosenge Likongo, Richard Kapela Mvwala, Raphael Nzau Kapend Mubunda, Noellie Kanka Mukuna, Julie Djondo Pembe, Nicolas Lumuanga Ndaye (Elsevier, 2021)
      Background Risk of mortality following surgery in patients across Africa is twice as high as the global average. Most of these deaths occur on hospital wards after the surgery itself. We aimed to assess whether enhanced ...
    • Heart disease and stroke statistics—2017 update: a report from the American Heart Association 

      Emelia J Benjamin, Michael J Blaha, Stephanie E Chiuve, Mary Cushman, Sandeep R Das, Rajat Deo, Sarah D De Ferranti, James Floyd, Myriam Fornage, Cathleen Gillespie, Carmen R Isasi, Monik C Jimenez, Lori Chaffin Jordan, Suzanne E Judd, Daniel Lackland, Judith H Lichtman, Lynda Lisabeth, Simin Liu, Chris T Longenecker, Rachel H Mackey, Kunihiro Matsushita, Dariush Mozaffarian, Michael E Mussolino, Khurram Nasir, Robert W Neumar, Latha Palaniappan, Dilip K Pandey, Ravi R Thiagarajan, Mathew J Reeves, Matthew Ritchey, Carlos J Rodriguez, Gregory A Roth, Wayne D Rosamond, Comilla Sasson, Amytis Towfighi, Connie W Tsao, Melanie B Turner, Salim S Virani, Jenifer H Voeks, Joshua Z Willey, John T Wilkins, Jason HY Wu, Heather M Alger, Sally S Wong, Paul Muntner (Lippincott Williams & Wilkins, 2017)
      Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings together in a single document ...
    • Immediate postoperative pain management in adult patients following orthopaedic surgery at the Kenyatta national hospital 

      Unknown author (University of Nairobi, 2007)
      Background: Postoperative pain is a major challenge in the care of surgical patients yet pain therapy is a central medical task and a legal duty and optimum pain control is a fundamental right for all patients. Objective: ...
    • Intentional Unilateral Epidural Block for Surgery in a Pregnant Patient 

      S Okelo, JG Kabugi (AJOL, 2013)
      Unilateral epidural block often results inadvertently during routine epidurals. It can however be used intentionally to provide analgesia selectively to the limb being operated. We present an application of this approach ...
    • Patient care and clinical outcomes for patients with COVID-19 infection admitted to African high-care or intensive care units (ACCCOS): a multicentre, prospective, observational cohort study 

      Bruce M Biccard, Pragasan Dean Gopalan, Malcolm Miller, William Lance Michell, David Thomson, Adesoji Ademuyiwa, Ernest Aniteye, Greg Calligaro, Maman Sani Chaibou, Hailu Tamiru Dhufera, Mohamed Elfagieh, Mahmoud Elfiky, Muhammed Elhadi, Maher Fawzy, David Fredericks, Meseret Gebre, Abebe Genetu Bayih, Anneli Hardy, Ivan Joubert, Fitsum Kifle, Hyla-Louise Kluyts, Kieran Macleod, Zelalem Mekonnen, Mervyn Mer, Atilio Morais, Vanessa Msosa, Wakisa Mulwafu, Andrew Ndonga, Zipporah Ngumi, Akinyinka Omigbodun, Christian Owoo, Fathima Paruk, Jenna Lynn Piercy, Juan Scribante, Yakob Seman, Elliott Taylor, Dawid van Straaten, Ahmed Awad, Hend Hussein, Mahmoud Shaban, Merihan Elbadawy, Ahmed O Elmehrath, Ahmed Cordie, Mohamed Elganainy, Mostafa El-Shazly, Mahmoud Essam, Omar A Abdelwahab, Aboubakr Ali, Aliae Mohamed Hussein, Fatma A Monib, Islam Ahmed, Mahmoud M Saad, Mohammed Ali Al-Quossi, Nashwa Rafaat, Islam Galal, Dalia Omran Omran, Ahmed Azzam, Mohammed Azab, Ahmed Tawheed, Mahmoud Gamal, Mohamed El Kassas, Aml Azzam, Neama Ahmed, Yasmin NasrEldin, Omar Abdewahab, Omar Elmandouh, Meseret MeGebre, Abebe Addisie, Akine Eshete, Kokeb Desita, Hiruy Araya, Yared Agidew, Addisu Desalegn Andabo, Emnet Tesfaye, Elias Ali Yesuf, Gelaw Hailemariam, Menbeu Sultan Mohammed, Yemane Gebremedhin, Yoseph Taye, Tamiru Assefa Mebrate, Tirunesh Busha Gemechu, Tigist Tesfaye Bedane, Elias Tewabe Abera, Ayele Teshome, Ernest Aniteye Ernest Aniteye, Christian Owoo Christian Owoo, Alfred Doku, Jane Sandra Afriyie-Mensah, Aba Lawson, Daniel Akwanfo DYaw Sottie, Emma Addae, Ernest Ofosu-Appiah Ernest Ofosu-Appiah, William Obeng William Obeng, Anne Mugera, Caesar Bitta, Mohammed Abdalraheem Huwaysh, Mohammed Mahdi Ali Yahya, Alsnosy Abdullah Khalefa Mohammed, Amrajaa Alsalihin Mohammed Majeed, Amkhatirah Emad Mousay Mohammed, Elsalhein Majeed, Abdurraouf A Abusalama, Ehab Altayr, Taha Abubaker, Akram Mohammed Alkaseek, Butaina Abdulhafith, Zainab Alziyituni, Marwa F Gamra, Mohamed Muftah Anaiba, Samer Khel, Mohammed Abdelkabir, Saedah Abdeewi, Safia Adam, Abdulmueti Alhadi, Ahmed Alsoufi, Muhannad Hassan, Ahmed Msherghi, Ahmad Elmabri Mohammad Bouhuwaish, Francis Masoo, Singatiya stella Chikumbanje, Delia Mabedi, Antonio Carlos, Cesaltina Lorenzoni, Jorge Mambo, Isabel Isabel Chissaque, Mouzinho Mouzinho Saide, Maikassoua Mamane, Foumakoye Amadou, Adesoji Ademuyiwa Adesoji Ademuyiwa, Akinyinka Omigbodun Akinyinka Omigbodun, Ademola Adeyeye, Akinola Akinmade, Yakubu Momohsani, John Bamigboye, Donald Orshio, Erdoo Suckie Isamade, Henry Embu, Samuel Nuhu, Samuel Ojiakor, Ahmed Nuhu, Adeola Fowotade, Arinola Sanusi, Babatunde Osinaike, Olusola Idowu, Abdullahi Oteikwu Amali, Sanusi Ibrahim, Adamu Abba Adamu, Ibrahim Kida, Job Otokwala, Olubusola Alagbe-Briggs (Elsevier, 2021)
      Background Molecular imaging is increasingly used to guide treatment decisions and planning in prostate cancer. We aimed to evaluate the role of 18F-fluciclovine-PET/CT in improving cancer control compared with conventional ...