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Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin–piperaquine versus intermittent preventive treatment with sulfadoxine …

Meghna Desai, Julie Gutman, Anne L'lanziva, Kephas Otieno, Elizabeth Juma, Simon Kariuki, Peter Ouma, Vincent Were, Kayla Laserson, Abraham Katana, John Williamson, Feiko O ter Kuile (Elsevier, 2015)

Background Every year, more than 32 million pregnancies in sub-Saharan Africa are at risk of malaria infection and its adverse consequences. The effectiveness of the intermittent preventive treatment with sulfadoxine–py ...

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-infected women receiving cotrimoxazole prophylaxis: a multicenter randomized placebo-controlled

Raquel González, Meghna Desai, Eusebio Macete, Peter Ouma, Mwaka A Kakolwa, Salim Abdulla, John J Aponte, Helder Bulo, Abdunoor M Kabanywanyi, Abraham Katana, Sonia Maculuve, Alfredo Mayor, Arsenio Nhacolo, Kephas Otieno, Golbahar Pahlavan, María Rupérez, Esperança Sevene, Laurence Slutsker, Anifa Vala, John Williamsom, Clara Menéndez (Public Library of Science, 2014)

Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women ...

Barriers and facilitators to antenatal and delivery care in western Kenya: a qualitative study

Linda Mason, Stephanie Dellicour, Feiko Ter Kuile, Peter Ouma, Penny Phillips-Howard, Florence Were, Kayla Laserson, Meghna Desai (BioMed Central, 2015)

Background In western Kenya, maternal mortality is a major public health problem estimated at 730/100,000 live births, higher than the Kenyan national average of 488/100,000 women. Many women do not attend antenatal care ...

An analysis of pregnancy-related mortality in the KEMRI/CDC health and demographic surveillance system in western Kenya

Meghna Desai, Penelope A Phillips-Howard, Frank O Odhiambo, Abraham Katana, Peter Ouma, Mary J Hamel, Jackton Omoto, Sheila Macharia, Annemieke van Eijk, Sheila Ogwang, Laurence Slutsker, Kayla F Laserson (Public Library of Science, 2013)

Background: Pregnancy-related (PR) deaths are often a result of direct obstetric complications occurring at childbirth. Methods and Findings: To estimate the burden of and characterize risk factors for PR mortality, we ...

Effectiveness of antenatal clinics to deliver intermittent preventive treatment and insecticide treated nets for the control of malaria in pregnancy in Kenya

Jenny Hill, Stephanie Dellicour, Jane Bruce, Peter Ouma, James Smedley, Peter Otieno, Maurice Ombock, Simon Kariuki, Meghna Desai, Mary J Hamel, Feiko O ter Kuile, Jayne Webster (Public Library of Science, 2013)

Background: Malaria in pregnancy can have devastating consequences for mother and baby. Coverage with the WHO prevention strategy for sub-Saharan Africa of intermittent-preventive-treatment (IPTp) with two doses of ...

Antenatal and delivery care in rural western Kenya: the effect of training health care workers to provide" focused antenatal care"

Peter O Ouma, Anna M van Eijk, Mary J Hamel, Evallyne S Sikuku, Frank O Odhiambo, Kaendi M Munguti, John G Ayisi, Sara B Crawford, Piet A Kager, Laurence Slutsker (BioMed Central, 2010)

Background Maternal mortality remains high in developing countries and data to monitor indicators of progress in maternal care is needed. We examined the status of maternal care before and after health care worker (HCW) ...

User and provider acceptability of intermittent screening and treatment and intermittent preventive treatment with Dihydroartemisinin-Piperaquine to prevent malaria in …

Jenny Hill, Jenna Hoyt, Florence Achieng, Peter Ouma, Anne L’lanziva, Simon Kariuki, Meghna Desai, Jayne Webster (Public Library of Science, 2016)

Background The World Health Organization recommends intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) alongside long-lasting insecticide-treated nets (LLIN) and case management ...

Stephanie Dellicour, Meghna Desai, George Aol, Martina Oneko, Peter Ouma, Godfrey Bigogo, Deron C Burton, Robert F Breiman, Mary J Hamel, Laurence Slutsker, Daniel Feikin, Simon Kariuki, Frank Odhiambo, Jayesh Pandit, Kayla F Laserson, Greg Calip, Andy Stergachis, Feiko O Ter Kuile

Risks of miscarriage and inadvertent exposure to artemisinin derivatives in the first trimester of pregnancy: a prospective cohort study in western Kenya (BioMed Central, 2015)

Background The artemisinin anti-malarials are widely deployed as artemisinin-based combination therapy (ACT). However, they are not recommended for uncomplicated malaria during the first trimester because safety data from ...

Birth preparedness and complication readiness among women attending antenatal care clinic in health facilities within Bureti sub county of Kericho county, Kenya

Phanice K Omari, Yaw A Afrane, Peter Ouma (2016)

Maternal mortality remains a major public health problem in Kenya with 488 deaths per 100,000 live births. Birth preparedness and complication readiness is one of the recommended strategies by the major global initiatives ...

Weekly miscarriage rates in a community-based prospective cohort study in rural western Kenya

Stephanie Dellicour, George Aol, Peter Ouma, Nicole Yan, Godfrey Bigogo, Mary J Hamel, Deron C Burton, Martina Oneko, Robert F Breiman, Laurence Slutsker, Daniel Feikin, Simon Kariuki, Frank Odhiambo, Gregory Calip, Andreas Stergachis, Kayla F Laserson, Feiko O Ter Kuile, Meghna Desai (British Medical Journal Publishing Group, 2016)

Objective: Information on adverse pregnancy outcomes is important to monitor the impact of public health interventions. Miscarriage is a challenging end point to ascertain and there is scarce information on its rate ...