• Login
    • Login
    Advanced Search
    View Item 
    •   Maseno IR Home
    • Journal Articles
    • School of Medicine
    • Department of Pathology
    • View Item
    •   Maseno IR Home
    • Journal Articles
    • School of Medicine
    • Department of Pathology
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    AMER SOC TROP MED & HYGIENE

    Thumbnail
    View/Open
    108 jmscr.pdf (560.4Kb)
    Publication Date
    2018
    Author
    AMER SOC TROP MED & HYGIENE
    Metadata
    Show full item record
    Abstract/Overview
    Background: Diagnosis of various causes of vaginal discharge is done by detailed history taking, physical examination and laboratory investigations. Use Nugent’s score as laboratory tests remains the gold standard however, its use presents challenges in resource limited set ups. Bacterial vaginosis (BV) result from supplanted Lactobacillus species leading to disruption in the normal vaginal microbiome. Objective: The main aim of the study was to evaluate vaginal cytology through clue cell detection and Nugent’s score in the laboratory diagnosis of BV in women of reproductive age. Specifically, the study determined the association between vaginal pH and the quantity of clue cells in BV, and the correlation between vaginal pH and polymorphonuclear cell in BV among non-pregnant women of reproductive age residents this Kisumu County. Methodology: The study was done at Jaramogi Oginga Odinga Teaching and Referral Hospital in 238 female participants aged (15-49yrs) presenting with vaginal discharge at Family Planning and Out Patient Department clinics. Clinical examination was done and laboratory specimens were collected to investigate the causative pathogens of vaginal discharge. Nugent’s score was performed to detect bacterial morphotypes and clue cell in BV using one swab while the other swab was used for high vaginal swab examination was performed using wet mount technique. Results: Results revealed positive correlation between clue cells and vaginal pH (ῥ=0.597, P<0.001). At the same time women without BV [mean (SEM), 4.32 (± 0.05)] had significantly low vaginal pH relative to those with BV [mean (SEM), 4.90, (± 0.05)], P<0.001. Moreover there was, positive correlation between vaginal pH and PMNs (ῥ=0.271, P<0.001). Conclusion: Clue cell detection and vaginal pH are the most useful criteria in the diagnosis of BV among symptomatic patients in resource limited settings as confirmed by the determined associations. However, PMNs should not be considered a criterion in diagnosis of BV even if it correlates well with vaginal pH
    Permalink
    https://repository.maseno.ac.ke/handle/123456789/3344
    Collections
    • Department of Pathology [17]

    Maseno University. All rights reserved | Copyright © 2022 
    Contact Us | Send Feedback

     

     

    Browse

    All of Maseno IRCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    Maseno University. All rights reserved | Copyright © 2022 
    Contact Us | Send Feedback