School of Medicine: Recent submissions
Now showing items 61-80 of 567
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Evaluation of changes in coagulation factors in fresh frozen plasma during storage at -18°C for 5 weeks at Kisii Teaching and Referral Hospital.
(Medrxiv, 2023)Background: Fresh frozen plasma is a critical substitute therapy in management of bleeding. Increased risk of venous thrombosis has been described to be associated with high plasma levels of several coagulation ... -
Rationale, Design, and the Baseline Characteristics of the RHDGen (The Genetics of Rheumatic Heart Disease) Network Study†
(AHA, 2023)BACKGROUND: The genetics of rheumatic heart disease (RHDGen) Network was developed to assist the discovery and validation of genetic variations and biomarkers of risk for rheumatic heart disease (RHD) in continental ... -
A patient with leishmaniasis presenting with longstanding pancytopenia and hepatosplenomegaly
(Wiley Online Library, 2023-02-10)Leishmaniasis is a common cause of pancytopenia and hepatosplenomegaly in tropical and subtropical regions. A high index of suspicion is required to diagnose and manage patients with leishmaniasis. Travel history should ... -
The ameliorative effects of graded intensities of exercise training on anthropometrical parameters on high fat diet and sucrose-induced obesity in Wistar rats
(AJOL, 2023)Obesity is a condition characterised by the expansion of visceral adipose tissue (VAT) depots, leading to its abnormal function, which is associated with the development of insulin insensitivity, cardiovascular disorders, ... -
Surgery is really a team sport
(Elsevier, 2022)A surgical team consists of healthcare professionals from various disciplines, all with different priorities, roles, expertise, and experience. This interdisciplinary team relies on the skills of all members and conducts ... -
Partnering to deliver sustainable children's surgical care in Kakuma refugee camp
(Elsevier, 2023)The devastating milestone of 100 million people globally forced to flee their homes because of war, violence, persecution, and discrimination was reached on May 23, 2022.1 Women and children are disproportionately affected. ... -
Human NCR3 gene variants rs2736191 and rs11575837 influence susceptibility to the longitudinal development of pediatric severe malarial anemia
(Research square, 2022)Plasmodium falciparum malaria is a leading cause of pediatric morbidity and mortality in holoendemic transmission areas. Severe malarial anemia [SMA, hemoglobin (Hb) < 5.0g/dL] is the most common clinical manifestation ... -
Mutations in Mycobacterium tuberculosis that Confers Resistance to First Line and Second Line Anti Tuberculosis agents in Western Kenya
(AJOL, 2022)Tuberculosis drug resistance remains a global, regional as well as a national public health concern, and is driven by point mutations in the Mycobacterium tuberculosis genome. However, their frequencies vary geographically ... -
Association among Cases of Women with first degree Family History of Diabetes Mellitus, Previous Macrosomia and Preterm Births, and Pregnancy Weight Gain at Mama Lucy Kibaki Hospital, Nairobi City
(EAST AFRICAN NATURE & SCIENCEORGANIZATION, 2023)Weight gain during pregnancy is of great concern for most women and obstetricians because of its possible consequences. This concern exists because gestational weight gain that exceeds what is recommended ... -
Association among Cases of Pregnancy Weight Gain, Gestational Diabetes Mellitus and Neonatal Delivery Outcomes at Mama Lucy Kibaki Hospital, Nairobi City
(Scientific Research Publishing, 2023)Gestational Weight Gain and Gestational Diabetes Mellitus are interrelated and are also closely associated with adverse neonatal deliveries namely macrosomia and preterm births. However, available literature does not ... -
Rationale, Design, and the Baseline Characteristics of the RHDGen (The Genetics of Rheumatic Heart Disease) Network Study
(Lippincott Williams & Wilkins, 2023)The genetics of rheumatic heart disease (RHDGen) Network was developed to assist the discovery and validation of genetic variations and biomarkers of risk for rheumatic heart disease (RHD) in continental Africans, as a ... -
The ameliorative effects of graded intensities of exercise training on anthropometrical parameters on high fat diet and sucrose-induced obesity in Wistar rats
(JAGST, 2023)Obesity is a condition characterised by the expansion of visceral adipose tissue (VAT) depots, leading to its abnormal function, which is associated with the development of insulin insensitivity, cardiovascular disorders, ... -
Association of Plasma Aflatoxin With Persistent Detection of Oncogenic Human Papillomaviruses in Cervical Samples From Kenyan Women Enrolled in a Longitudinal Study
(Research Square, 2023)Cervical cancer is common among Kenyan women and is caused by oncogenic human papillomaviruses (HR-HPV). Identification of factors that increase HR-HPV persistence is critically important. Kenyan women exposed to aflatoxin ... -
The Burden of Motorcycle Crash Injuries on the Public Health System in Kisumu City, Kenya
(Global Health Science, 2023)Background: In Kenya, the increased use of motorcycles for transport has led to increased morbidity, mortality, and disability. These injuries exert a burden on the public health system, yet little information exists ... -
Quality of Medical Care at the Emergency Departments of Public Hospitals in Kenya
(EAST AFRICANNATURE & SCIENCEORGANIZATION, 2022)Globally, states are obliged to prioritize quality medical care at emergency departments (EDs). Kenya is not an exception since medical care services are mainly offered in the outpatient departments. However, the quality ... -
Immunization of Rabbits with a Quadrivalent Shigella Bioconjugate Vaccine Induces Functional Antibodies Reactive with Shigella Isolates from Kenya
(American Society for Microbiology, 2022)Diarrheal diseases are a leading cause of global morbidity and mortality, disproportionately affecting children in resource-limited settings. Although improvements in hygiene and access to clean water are helpful, vaccines ... -
Effects of Training Small-Scale Farmers on Food Security in Moiben Sub County in Uasin Gishu County
(EANSO, 2022)Food security revolves around equality in the availability, access, and intake of nutritious food. The main purpose of this research is to determine the effectiveness of the adoption of agricultural technologies by small-scale ... -
Haemostatic disorders in patients with breast cancer at Kenyatta national hospital, Kenya
(University of Nairobi, 2010)Haemostatic disorders (thrombosis and haemorrhage) are increasingly being investigated and assessed as factors that influence outcome of treatment of solid tumors including breast cancer. There is little data available ... -
Patient Characteristics from an Emergency Care Center in Rural Western Keny
(Maseno University, 2019)Emergency care is a neglected area of focus in many low- and middle-income countries. There is a paucity of research on types and frequencies of acute illnesses and injuries in low-resource settings. -
Selected genes of Human herpesvirus-8 associated Kaposi’s sarcoma among patients with Human Immunodeficiency Virus-1 and Acquired Immunodeficiency Disease Syndrome
(AJOL, 2019)Kaposi's sarcoma (KS) is a kind of cancer that causes flat or raised lesions containing Human herpes virus 8 (HHV8). The KS lesions are common among immunosuppressed HIV patients. Highly Active Antiretroviral (HHART) treats ...