School of Medicine: Recent submissions
Now showing items 261-280 of 553
-
Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-infected women receiving cotrimoxazole prophylaxis: a multicenter randomized placebo-controlled
(Public Library of Science, 2014)Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women ... -
Effect of malaria rapid diagnostic tests on the management of uncomplicated malaria with artemether-lumefantrine in Kenya: a cluster randomized trial
(The American Society of Tropical Medicine and Hygiene, 2009)Shortly after Kenya introduced artemether-lumefantrine (AL) for first-line treatment of uncomplicated malaria, we conducted a pre-post cluster randomized controlled trial to assess the effect of providing malaria rapid ... -
Antifolate Resistance in Plasmodium falciparum: Multiple Origins and Identification of Novel dhfr Alleles
(The University of Chicago Press, 2006)BackgroundSulfadoxine-pyrimethamine has been widely used as first-line therapy for uncomplicated malaria throughout sub-Saharan Africa. Recent studies conducted in Asia and Africa suggest the triple-mutant dhfr genotype ... -
Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin–piperaquine versus intermittent preventive treatment with sulfadoxine …
(Elsevier, 2015)Background Every year, more than 32 million pregnancies in sub-Saharan Africa are at risk of malaria infection and its adverse consequences. The effectiveness of the intermittent preventive treatment with sulfadoxine–py ... -
Barriers and facilitators to antenatal and delivery care in western Kenya: a qualitative study
(BioMed Central, 2015)Background In western Kenya, maternal mortality is a major public health problem estimated at 730/100,000 live births, higher than the Kenyan national average of 488/100,000 women. Many women do not attend antenatal care ... -
Quality of post abortion care services in Bungoma District hospital, Kenya
(University of Nairobi,, 2010)Background: Abortion is the commonest complication of early pregnancy occurring in 10% - 15% of pregnancies. The demand for Post Abortion Care remains high in hospitals in Kenya. The public health rationale to address ... -
Vaginal hysterectomy as a primary approach of in managing benign gynecological conditions. A review of local practice.
(KOGS, 2016)Background: Hysterectomy is the commonest major gynaecological surgery performed. Traditionally this has been done abdominally, although the vaginal route could confer more benefits if well performed. Objective: To ... -
Toward Cervical Cancer Elimination: Evaluation of Access to Diagnostic Services After Referral to a Specialist Gynecologist Clinic at a Major Referral Hospital in Kisumu, Kenya
(American Society of Clinical Oncology, 2020)PURPOSE Women in low- and middle-income countries bear a disproportionate burden of cervical cancer incidence and mortality. WHO recommends screening with visual inspection with acetic acid (VIA), followed by treatment ... -
Assessing quality of life among gynaecological cancer patients receiving care in the palliative care unit at Kenyatta national hospital
(University of Nairobi, 2014)Quality of life (QOL) assessment among cancer patients is considered to be an important aspect in palliative care. QOL assessment helps in the identification of the physical, psychological, social and spiritual needs of ... -
Levels of Compliance to Proposed Hemodialysis Treatment Standards by Nurses at Kenyatta National Hospital, Kenya
(Scientific & Academic Publishing. A, 2017)Compliance with treatment standards helps to improve health outcomes and prevent complications. This study sought to determine the level of compliance to hemodialysis treatment standards among nurses in the renal unit at ... -
The Role of Mobile Health in Supporting Cancer Prevention, Detection, Treatment and Palliative Care in Low and Middle Income Countries: A Scoping Review
(Scientific & Academic Publishing, 2017)Cancer is one of the non-communicable diseases with high morbidity and mortality rates, particularly in low-and-middle income countries. Increasing cancer burden is attributable to lifestyle risk factors, poor health ... -
Case Management of Substance Induced Psychosis Using Peplau’s Theory of Interpersonal Relations
(2017)Substance induced psychosis is a form of psychosis that develops from the use of alcohol or other drugs. The symptoms for this form of psychosis can resolve within days or weeks though tendencies of relapsing occur with ... -
Quality of life among gynaecological cancer patients receiving palliative care in Kenya: A cross-sectional study
(MA Healthcare, 2016-01-02)Background/Aims: Cancer and its treatment affects the quality of life in patients. In Africa, there is limited research available on the quality of life among cancer patients. This study describes quality of life in ... -
Determinants of quality of life among gynaecological cancer patients on follow up at a referral hospital in Kenya
(University of Nairobi, 2015-06-08)Various factors influence the quality of life (QOL) in cancer patients. This study sought to determine the predictors and factors associated with quality of life among g ynaecological cancer patients on follow up at Kenya ... -
Alcohol use among khat (Catha) chewers in Kenya
(Blackwell Publishing Ltd, 1987-01)Among one hundred randomly selected outpatients at the Meru District Hospital in Kenya, 29 (28 men and 1 woman) were Khat chewers. Six of these were ‘heavy’ and 23 ‘moderate’ users. Twenty out of 29 Khat chewers also used ... -
Prevalence of khat chewers among primary health clinic attenders in Kenya
(Blackwell Publishing Ltd, 1987-03)In a rural district hospital in Kenya, the authors screened 100 randomly selected outpatients for khat (miraa) chewing. A surprisingly high number of them admitted chewing khat leaves. The implications of this finding and ... -
Alcohol use among khat (Catha) chewers in Kenya
(Blackwell Publishing Ltd, 1987-01)Among one hundred randomly selected outpatients at the Meru District Hospital in Kenya, 29 (28 men and 1 woman) were Khat chewers. Six of these were ‘heavy’ and 23 ‘moderate’ users. Twenty out of 29 Khat chewers also used ... -
Characteristics of psychosocial support seeking during HIV-related treatment in western Kenya
(Mary Ann Liebert, Inc., 2008-07-01)While the characteristics of those who seek psychosocial support following an HIV diagnosis have been well documented in western countries where linkages between HIV-related treatment and psychosocial support programs are ... -
Validity/reliability of PHQ-9 and PHQ-2 depression scales among adults living with HIV/AIDS in western Kenya
(Springer-Verlag, 2009-02-01)Background Depression greatly burdens sub-Saharan Africa, especially populations living with HIV/AIDS, for whom few validated depression scales exist. Patient Health Questionnaire-9 (PHQ-9), a brief dual-purpose instrument ... -
Systematic cultural adaptation of cognitive-behavioral therapy to reduce alcohol use among HIV-infected outpatients in western Kenya
(Springer US, 2010-06-01)Two-thirds of those with HIV worldwide live in sub-Saharan Africa. Alcohol use is associated with the HIV epidemic through risky sex and suboptimal ARV adherence. In western Kenya, hazardous drinking was reported by HIV ...