School of Medicine: Recent submissions
Now showing items 201-220 of 553
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A ten-year study of Retinoblastoma in Uganda: An approach to improving outcome with limited resources
(Elsevier, 2021)Background: Survival of children with cancer in resource-limited regions is very poor compared to betterresourced regions. Retinoblastoma (RB) is a childhood cancer that is commonly reported in many regions of Africa. RB ... -
Determinants of Uptake of Intermittent Preventive Treatment for Malaria among Pregnant Women in Suba Sub-County, Homabay County, Kenya
(International Journal of Innovative Research and Development, 2020)Background: Intermittent preventive treatment of malaria in pregnancy (IPTp) is one of the effective and efficacious interventions recommended for prevention of malaria in pregnancy. The drug of choice is Sulphadoxine-Py ... -
Patient care and clinical outcomes for patients with COVID-19 infection admitted to African high-care or intensive care units (ACCCOS): a multicentre, prospective, observational cohort study
(Elsevier, 2021)Background Molecular imaging is increasingly used to guide treatment decisions and planning in prostate cancer. We aimed to evaluate the role of 18F-fluciclovine-PET/CT in improving cancer control compared with conventional ... -
Feasibility and Acceptability of Smartphone-Based Cervical Cancer Screening Among HIV-Positive Women in Western Kenya
(Gynecologic Cancer, 2021)PURPOSE Adjunct cervical cancer screening methods are under evaluation to improve the diagnostic accuracy of human papillomavirus (HPV)-based screening in low- and middle-income countries. We evaluated the feasibility and ... -
Hepatitis B and C virus co-infections and genetic diversity among HIV-1 infected individuals in Siaya County, Kenya
(EAST AFRICAN MEDICAL JOURNAL, 2021)Objectives: The present study determined the prevalence of HBV/HCV coinfections; genetic diversity and drug resistance of HBV among HIV infected patients visiting Siaya County Referral Hospital, Kenya. Design: This was ... -
Molecular identification and antibiotic susceptibility patterns of bacterial isolates from urine samples of African buffalo, eland and cattle
(International Journal of Applied Biology, 2021)Presence of antibiotic resistant bacteria in natural environment is an escalating risk of serious implication on human and animal health. Livestock and wildlife have been long recognized as reservoirs for antibiotic resistant ... -
Burden of disease and risk factors for mortality amongst hospitalized newborns in Nigeria and Kenya
(Public Library of Science, 2021)Objective To describe the patient population, priority diseases and outcomes in newborns admitted <48 hours old to neonatal units in both Kenya and Nigeria. Study design In a network of seven secondary and tertiary ... -
Case report: Acute Kidney Injury, Liver impairment, Severe Anemia in a child with Malaria and Hyperparasitaemia
(Global Journal of Medical and Clinical Case Report, 2021)Severe Malaria is a medical emergency mainly because of its rapid progression to complications and death if not promptly and adequately treated. In 2018 WHO put the incidence of P. falciparum Malaria in the African region ... -
Clinical laboratory hematology reference values among infants aged 1month to 17 months in Kombewa Sub-County, Kisumu: A cross sectional study of rural population in Western Kenya
(Public Library of Science, 2021)There is an urgent need for reliable region-specific hematological reference values for clinical monitoring. Laboratory reference ranges are important for assessing study participant eligibility, toxicity grading and ... -
Combined chemotherapy manifest less severe immunopathology effects in helminth-protozoa comorbidity
(Experimental parasitology, 2019)Background Co-infection with Leishmania major and Schistosoma mansoni may have significant consequences for disease progression, severity and subsequent transmission dynamics. Pentavalent antimonials and Praziquantel (PZQ) ... -
Microscopy Underestimates the Prevalence of Trypanosomes’ Infection in Asymptomatic Cattle and Sheep in a Lowland Area within the Kenyan Rift Valley
(Scientific Research Publishing, 2019)Animal trypanosomosis continues to impede animal production in sub-Saharan Africa mostly in locations where tsetse flies are endemic. This has ended up devastating many livelihoods where majority of the people depend on ... -
Identity, Preparation, Dosages and Conservation Knowledge of the Antidiabetic Herbs Used by The Tugen Living in Baringo County-Kenya
(African Journal of Health Sciences, 2020)The primary goal of managing Diabetes Mellitus (DM) is to regulate blood sugar levels within the physiologic limits (3Mmol/l to7Mmmol/l-fasting blood sugars). This can be either done pharmacologically (conventional or ... -
Effects of Allium Sativum Ethanolic Extract on Trypanosoma brucei brucei Parasites’ Morphometric Parameters and Clinical Outcome in White Albino Laboratory Rats
(African Journal of Health Sciences, 2021)Background: Trypanosomosis affects humans as well as wild and domestic vertebrates, yet has no successful prophylaxis, chemotherapy nor cure. Objectives: The study was to investigate the effects of Allium sativum extract ... -
Intensity, duration and frequency of exercise needed to achieve change in metabolic profiles in prediabetes at Moi Teaching and Referral Hospital in Uasin Gishu County in Kenya
(East African Medical Journal, 2021)Objective: To establish the intensity, duration and frequency of exercise needed to achieve change in metabolic profiles of pre-diabetes at Moi Teaching and Referral Hospital, Eldoret, Kenya. Design: A randomized ... -
SEROPREVALENCE OF CHLAMYDOPHILA PSITTACIAMONG EMPLOYEES OF TWO GERMAN DUCK FARMS
(Akadémiai Kiadó, 2017)Psittacosis is a zoonotic infectious disease that is caused by Chlamydophila psittaci. To determine the occupational risk of getting the infection, we investigated the seroprevalence of C. psittaci among employees of two ... -
Proteotyping as alternate typing method to differentiate Campylobacter coli clades
(Nature Publishing Group, 2019)Besides Campylobacter jejuni, Campylobacter coli is the most common bacterial cause of gastroenteritis worldwide. C. coli is subdivided into three clades, which are associated with sample source. Clade 1 isolates are ... -
Proteome Profiling by Label‐Free Mass Spectrometry Reveals Differentiated Response of Campylobacter jejuni 81–176 to Sublethal Concentrations of Bile Acids
(PROTEOMICS–Clinical Applications, 2019)Purpose Bile acids are crucial components of the intestinal antimicrobial defense and represent a significant stress factor for enteric pathogens. Adaptation processes of Campylobacter jejuni to this hostile environment ... -
Factors influencing anti-retroviral therapy uptake among HIV positive and exposed children aged below 14 years in Meru North District, Kenya
(EAST AFRICAN MEDICAL JOURNAL, 2018)Anti-retroviral Therapy (ART) is a major intervention for children infected and exposed to HIV infection and it influences their morbidity and mortality.Objective: To investigate factors influencing ARV uptake in HIV ... -
The Role of Income Generating Activities in Sustainable Retention of Community Health Volunteers in Primary Health-Care Service Provision in Bungoma County, Kenya
(Annals of Community Health, 2020)The role of community health volunteers (CHVs) in provision of primary health-care (PHC) has been widely acclaimed as poignant. CHVs help not only in addressing shortage in trained health workers but also in improving ... -
Esteem Needs and the Retention of Community Health Volunteers in Primary Health Care Service Provision in Bungoma County, Kenya
(Annals of Community Health, 2020)The main objective of this study was to investigate how the self-esteem of the Community health volunteers (CHVs) influences the retention of CHVs in primary health-care (PHC) service provision. The study design was ...