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HIV-1 progression links with viral genetic variability and subtype, and patient’s HLA type: analysis of a Nairobi-Kenyan cohort
(Springer Berlin Heidelberg, 2014-02-01)
In a Nairobi-Kenyan cohort of 50 HIV-1 positive patients, we analysed the prevalence of HIV-1 subtypes and human leucocyte antigen (HLA) alleles. From this cohort, 33 patients were selected for the analysis of HIV-1 infection ...
Prevalence of transmitted drug resistance mutations in HIV-1-infected drug-naive patients from urban and suburban regions of Kenya
(Mary Ann Liebert, Inc., 2016-03-01)
HIV was first described in Kenya in 1984–1985. Currently, Kenya has an estimated HIV-1 prevalence of 6.2%. With the introduction of antiretroviral drugs, the survival of most HIV patients has been prolonged markedly. ...
Population-specific evolution of HIV Gag epitopes in genetically diverged patients
(Elsevier, 2013-06-01)
Under the host selection pressure HIV evolves rapidly to override crucial steps in the antigen presentation pathway. This allows the virus to escape binding and recognition by cytotoxic T lymphocytes. Selection pressures ...
Macro CK in patients with elevated troponin I levels: case report: online article
(Clinics Cardive Publishing, 2012-02-01)
CK-MB activity levels can be falsely elevated by the presence of macro CK, especially if immuno-inhibition assays are used in the measurement. In patients with macro CK and cardiac pathology that could result in an elevated ...
Family history as a risk for early-onset type 2 diabetes in Kenyan patients.
(EBSCO Industries, Inc, 2014)
Early-onset type 2 diabetes is regarded as disease occurring before the age of 40 years. It is well described, and increasing in prevalence, but there is little information from Africa. We therefore assessed the prevalence ...
A novel ED-based sexual assault centre in western Kenya: description of patients and analysis of treatment patterns
(BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine, 2011-11-01)
he aim of this study was to establish the feasibility of a Kenyan emergency department (ED)-based sexual assault centre; and to improve knowledge of the characteristics of sexual assault in the region.
Vaginal hysterectomy as a primary approach of in managing benign gynecological conditions. A review of local practice.
(KOGS, 2016)
Hysterectomy is the commonest major gynaecological surgery performed. Traditionally this has been done abdominally, although the vaginal route could confer more benefits if well performed.
Quality of post abortion care services in Bungoma District hospital, Kenya
(University of Nairobi,, 2010)
Abortion is the commonest complication of early pregnancy occurring in 10% - 15% of pregnancies. The demand for Post Abortion Care remains high in hospitals in Kenya. The public health rationale to address abortions and ...
An assessment of facility-based care of diabetes, hypertension, and heart failure across western Kenya
(Kenya Medical Association, 2018)
Low- and middle- income countries account for three-fourths of the global non- communicable disease related mortality. In response to the increasing number of non- communicable disease diagnoses in Kenya, the government ...
Malignant obstructive jaundice: Factors predictive of non Resectability at kenyatta National Hospital
(University of Nairobi, 2010)
Malignant obstructive jaundice is a rising cause of mortality and morbidity in surgical patients worldwide. Most patients at time of presentation have advanced disease. Surgery remains the only curative mode of treatment ...