Browsing School of Medicine by Title
Now showing items 486-505 of 553
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Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa
(Taylor & Francis, 2019)A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS,S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children (enrolled ... -
Same day colposcopic examination and loop electrosurgical excision procedure (LEEP) presents minimal overtreatment and averts delay in treatment of cervical intraepithelial …
(Scientific Research Publishing, 2013-05-08)Background: Screening for cancer of the cervix at Kenyatta National Hospital (KNH), follows the recommended three-step strategy; Papanicolaou (Pap) smear, colposcopy/biopsy and loop electrosurgical excision procedure ... -
Screening of Bioactive Secondary Metabolites from Sea Sponge (Clathria Indica) Against Bacteria Associated with Urinary Tract Infections
(Journal of the Open University of Tanzania, 2013)The marine sponge Clathria indica, collected from Thondi-Palk Strait region of Tamil Nadu, was studied for bacterial antagonistic activity. Sponge species were identified based on specula morphology. Ethyl Acetate extracts ... -
Sehistosoma Mansoni in the Baboon: Modulation of Pathology After Vaccination with Polyclonal Anti‐Idiotypic Antibodies
(Blackwell Publishing Ltd, 1995-12-01)Vaccination of five baboons with an anti-idiotypic vaccine to irradiated Schistosoma mansoni cercariae resulted in nearly 19% protection compared to 39% protection conferred to five baboons vaccinated with an irradiated ... -
Selected genes of Human herpesvirus-8 associated Kaposi’s sarcoma among patients with Human Immunodeficiency Virus-1 and Acquired Immunodeficiency Disease Syndrome
(AJOL, 2019)Kaposi's sarcoma (KS) is a kind of cancer that causes flat or raised lesions containing Human herpes virus 8 (HHV8). The KS lesions are common among immunosuppressed HIV patients. Highly Active Antiretroviral (HHART) treats ... -
Selective Blockade of Trypanosomatid Protein Synthesis by a Recombinant Antibody Anti-Trypanosoma cruzi P2β Protein
(Public Library of Science, 2012-05-03)The ribosomal P proteins are located on the stalk of the ribosomal large subunit and play a critical role during the elongation step of protein synthesis. The single chain recombinant antibody C5 (scFv C5) directed against ... -
Sensitivity of 3D7 and W2 Clones in a Formulated Transport Medium and EDTA Anticoagulants against a Panel of Antimalarials
(Journal of Biology, Agriculture and Healthcare, 2016)Introduction: in vitro drug sensitivity relies on the growth of plasmodium in the presence of the antimalarials. These fresh isolates brought in for assay from collection sites normally not near the laboratory require a ... -
SEROPREVALENCE OF CHLAMYDOPHILA PSITTACIAMONG EMPLOYEES OF TWO GERMAN DUCK FARMS
(Akadémiai Kiadó, 2017)Psittacosis is a zoonotic infectious disease that is caused by Chlamydophila psittaci. To determine the occupational risk of getting the infection, we investigated the seroprevalence of C. psittaci among employees of two ... -
Seroprevalence of hepatitis B surface antigen and it’s associated factors among hiv positive pregnant women in Jaramogi Oginga Odinga Teaching and Referral
(University of Nairobi, 2015)Introduction: Hepatitis B Virus (HBV) and Human Immunodeficiency Virus (HIV) are among the leading causes of infectious disease deaths worldwide. The two viruses are highly endemic in sub-Saharan Africa. Pregnant women who ... -
Serum cystatin C for assessment of glomerular filtration rate in hypertensive disorders of pregnancy
(Taylor & Francis, 2004-01-01)Assessment of renal function is important in the evaluation of the pregnant hypertensive patient. The aim of this study was to evaluate the diagnostic utility of cystatin C as a marker of glomerular filtration rate in ... -
Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communiqué: cardiovascular topics
(Sabinet, 2016-05-01)Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major causes of heart failure, stroke and death among African women and children, despite being preventable and imminently treatable. From 21 to 22 ... -
Severe hyponatraemia in hospital inpatients
(BMJ Publishing Group, 1978-12-09) -
Sickle cell trait (HbAS) is associated with increased expression of erythrocyte complement regulatory proteins CR1 and CD55 levels in children
(International Journal of TROPICAL DISEASE & Health, 2013)Aims: Erythrocyte complement regulatory proteins, complement receptor 1 (CR1) and decay accelerating factor (CD55) protect red blood cells (RBCs) from complement mediated damage by controlling complement activation cascade ... -
Sigmoid volvulus in pregnancy
(Annals of African Surgery., 2019)Sigmoid volvulus in pregnancy is a rare condition that poses a myriad of challenges in diagnosis and management of the patient. It demands on the clinician a high index of suspicion, immediate treatment involving resuscitation ... -
Sigmoid volvulus in pregnancy
(The Surgical Society of Kenya, 2010)Sigmoid volvulus in pregnancy is a rare condition that poses a myriad of challenges in diagnosis and management of the patient. It demands on the clinician a high index of suspicion, immediate treatment involving resuscitation ... -
Single voxel magnetic resonance spectroscopy in distinguishing focal neoplastic from non-neoplatic brain lesions
(East African Medical Journal, 2011)Objective: Assess diagnostic utility of combined magnetic resonance imaging and magnetic resonance spectroscopy (MRI, MRS) in differentiating focal neoplastic lesions from focal non- neoplastic (infective or degenerative) ... -
Smartphone-based Ophthalmic Imaging Compared With Spectral-domain Optical Coherence Tomography Assessment of Vertical Cup-to-disc Ratio Among Adults in Southwestern Uganda
(NIH Public Access, 2021)Precis: Using optical coherence tomography (OCT) measurements as a reference standard for vertical cup-to-disc ratio (vCDR), a smartphone-based ophthalmic camera has a sensitivity of 67.7% and specificity of 96.7% to detect ... -
Socio-Cultural Support Systems For The Elderly And Its Implications For Formal Social Protection Programmes In Rural Western Kenya
(Academic Journals, 2015)The rising populations of the elderly and the various socio-cultural and economic changes that have taken place in the Luo community have had an impact on support systems for the elderly. However, there is little knowledge ... -
Spatial distribution and habitat characterisation of mosquito species in the lake and land habitats of western Kenya
(Kenya Medical Association, 2016) -
Spatial distribution and habitat characterization of mosquito species during the dry season along the Mara River and its tributaries, in Kenya and Tanzania
(BioMed Central, 2018)Background Vector-borne diseases are increasingly becoming a major health problem among communities living along the major rivers of Africa. Although larger water bodies such as lakes and dams have been extensively ...