Browsing School of Medicine by Title

Now showing items 237-256 of 553

    • Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality 

      Anyona, SB; Kempaiah, P; Raballah, E; Ouma, C; Were, T; Davenport, GC; Konah, SN; Vulule, JM; Hittner, JB; Gichuki, CW; Ong'echa, JM; Perkins, DJ (Pub Med Central, 2011-12)
      Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where Plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ...

    • Fusion of the Medial Clavicular Epiphysis in the South African and Kenyan Populations. 

      DO Marera, KS Satyapal (International Journal of Morphology, 2019)
      : Age estimation from clavicular ossification has been studied by many researchers based on the pattern and degree of the epiphyseal union through the use of dry bone specimens, radiographs, CT and MRI. These studies found ...

    • Fusión de la Epífisis Clavicular Medial en las Poblaciones de Sudáfrica y Kenia 

      DO Marera, KS Satyapal (Sociedad Chilena de Anatomía, 2019)
      Age estimation from clavicular ossification has been studied by many researchers based on the pattern and degree of the epiphyseal union through the use of dry bone specimens, radiographs, CT and MRI. These studies found ...

    • GalAactosaemia in black South African children 

      PJ Ojwang; T Manickum; WM Deppe (Kenya Medical Association, 1999)
      To evaluate the clinical and biochemical features of all black children confirmed to have galactosaemia from the KwaZulu Natal Province of South Africa.

    • Gender Influence on Changes of Coagulation Factors in Fresh Frozen Plasma at Kisii Teaching and Referral Hospital 

      Ogolla, Collince Odiwuor; Demba, Rodgers Norman (Opast Publishing Group, 2023-06-08)
      Fresh frozen plasma is a critical substitute therapy in management of bleeding. Increased risk of venous thrombosis has been described to be associated with high plasma levels of several coagulation factors.

    • Gender Role Strain and the Precarious Manhood of Sexual Minority Kenyan Men 

      Ricky M. Granderson, Gary W. Harper , Ryan Wade, Wilson Odero , Daniel P. Onyango Olwango and Errol L. Fields (American Psychological Association, 2020)
      Examining the impact of precarious manhood on the mental health of sexual minority men living in Kenya, we hypothesized that (a) men who have sex with men exclusively (MSME) and men who have sex with men and women (MSMW) ...

    • Genetic analysis of HIV-1 subtypes in Nairobi, Kenya 

      Suhail Khoja, Peter Ojwang, Saeed Khan, Nancy Okinda, Reena Harania, Syed Ali (Public Library of Science, 2008-09-11)
      Genetic analysis of a viral infection helps in following its spread in a given population, in tracking the routes of infection and, where applicable, in vaccine design. Additionally, sequence analysis of the viral genome ...

    • Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine 

      Daniel E Neafsey, Michal Juraska, Trevor Bedford, David Benkeser, Clarissa Valim, Allison Griggs, Marc Lievens, Salim Abdulla, Samuel Adjei, Tsiri Agbenyega, Selidji T Agnandji, Pedro Aide, Scott Anderson, Daniel Ansong, John J Aponte, Kwaku Poku Asante, Philip Bejon, Ashley J Birkett, Myriam Bruls, Kristen M Connolly, Umberto D’Alessandro, Carlota Dobaño, Samwel Gesase, Brian Greenwood, Jonna Grimsby, Halidou Tinto, Mary J Hamel, Irving Hoffman, Portia Kamthunzi, Simon Kariuki, Peter G Kremsner, Amanda Leach, Bertrand Lell, Niall J Lennon, John Lusingu, Kevin Marsh, Francis Martinson, Jackson T Molel, Eli L Moss, Patricia Njuguna, Christian F Ockenhouse, Bernhards Ragama Ogutu, Walter Otieno, Lucas Otieno, Kephas Otieno, Seth Owusu-Agyei, Daniel J Park, Karell Pellé, Dana Robbins, Carsten Russ, Elizabeth M Ryan, Jahit Sacarlal, Brian Sogoloff, Hermann Sorgho, Marcel Tanner, Thor Theander, Innocent Valea, Sarah K Volkman, Qing Yu, Didier Lapierre, Bruce W Birren, Peter B Gilbert, Dyann F Wirth (Massachusetts Medical Society, 2015)
      BACKGROUND The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium falciparum and has partial protective efficacy against clinical and severe malaria disease in infants and children. We investigated ...

    • Genetic diversity and relationships among populations of jackfruit, an underutilized nutrient-rich climate-smart fruit tree crop in Kenya and Uganda 

      OJWANG, Redemtor Awuor; MUGE, Edward K; NYABOGA, Evans N; MBATIA, Betty N; OGOYI, Dorington O (Taylor & Francis, 2022-09-03)
      Jackfruit (Artocarpus heterophyllus Lam.) is an underutilized fruit tree crop in East Africa. Despite its importance for food and nutritional security, only limited information exists on the extent of genetic variability ...

    • A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa 

      Sandra Van Puyvelde, Tessa De Block, Sushmita Sridhar, Matt Bawn, Robert A Kingsley, Brecht Ingelbeen, Mathew A Beale, Barbara Barbé, Hyon Jin Jeon, Lisette Mbuyi-Kalonji, Marie-France Phoba, Dadi Falay, Delphine Martiny, Olivier Vandenberg, Dissou Affolabi, Jean Pierre Rutanga, Pieter-Jan Ceyssens, Wesley Mattheus, Wim L Cuypers, Marianne AB Van Der Sande, Se Eun Park, Simon Kariuki, Kephas Otieno, John PA Lusingu, Joyce R Mbwana, Samuel Adjei, Anima Sarfo, Seth O Agyei, Kwaku P Asante, Walter Otieno, Lucas Otieno, Marc C Tahita, Palpouguini Lompo, Irving F Hoffman, Tisungane Mvalo, Chisomo Msefula, Fatimah Hassan-Hanga, Stephen Obaro, Grant Mackenzie, Stijn Deborggraeve, Nicholas Feasey, Florian Marks, Calman A MacLennan, Nicholas R Thomson, Jan Jacobs, Gordon Dougan, Samuel Kariuki, Octavie Lunguya (Nature Publishing Group UK, 2023-10-23)
      Invasive non-typhoidal Salmonella (iNTS) disease manifesting as bloodstream infection with high mortality is responsible for a huge public health burden in sub-Saharan Africa. Salmonella enterica serovar Typhimurium (S. ...

    • The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis 

      Douglas J Perkins, Tom Were, Samuel Anyona, James B Hittner, Prakasha Kempaiah, Gregory C Davenport, John Michael Ong’echa (Springer, New York, NY, 2013)
      Plasmodium falciparum malaria is a leading global cause of morbidity and mortality of infectious disease origin. Here, we focus largely on P. falciparum malaria in sub-Saharan Africa since this geographic region bears the ...

    • The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis 

      Douglas J. PerkinsEmail authorTom WereSamuel AnyonaJames B. HittnerPrakasha KempaiahGregory C. DavenportJohn Michael Ong’echa (Springer, 2012)
      Plasmodium falciparum malaria is a leading global cause of morbidity and mortality of infectious disease origin. Here, we focus largely on P. falciparum malaria in sub-Saharan Africa since this geographic region bears the ...

    • A global" School for Surgeons" could help bridge the Healthcare Human Resource Crisis in Sub-Saharan Africa 

      STEPHEN OGENDO, SWO Ogendo (University of Nairobi, 2009)
      Appropriately designed elearning programmes (including Best or School for Surgeons) may allow more efficient use of consultant teaching time. Using funding from Irish Aid, we piloted these existing e-learning tools in a ...

    • The growth and development outcomes of foetuses born of albino rats (Rattus Norvegicus) prenatally exposed to varying doses of lamotrigine 

      Wairimu Ann, Mwangi, Kariuki Joseph, Kweri, Kamau Cyrus, Kweri, Mwangi James, Kanyoni, Muriithi Alex, Kigundu, Githinji Elijah, Mwangi, Oduor Dominic, Marera (AJOL, 2023-05-16)
      The growth and development outcomes of the foetuses born by mothers who prenatally get exposed to lamotrigine (LAMT) have not been well established. Lamotrigine is an anticonvulsant medicine used in the management of acute ...

    • Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya 

      Paul Kosiyo, Walter Otieno, Jesse Gitaka, Elly O. Munde & Collins Ouma (Springer, 2021)
      In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ...

    • Haematological abnormalities in children with sickle cell disease and non-severe malaria infection in western Kenya 

      Paul Kosiyo, Walter Otieno, Jesse Gitaka, Elly O Munde, Collins Ouma (BioMed Central, 2021-12)
      In Plasmodium falciparum infection, clinical conditions such as anaemia, thrombocytopenia and leukocytosis are common. Mutation in haemoglobin sub-unit beta gene (HBB) may be a genetic factor responsible for these ...

    • Haematological Parameters by Age and Sex of Asymptomatic Indigenous Cattle and Sheep Infected with Gastrointestinal Parasites in Kerio Valley, Kenya 

      E. C. Ngetich1, 2,* , M. Ngeiywa2 , G. M. Ng’wena3 , Chemwolo L.4 (Science & Education Publishing, 2019)
      Gastro-intestinal parasites are prevalent and directly impede livestock production causing impaired productivity. Haematological parameters, which are likely to be influenced by parasites, are generally indicators of healthy ...

    • Haemostatic disorders in patients with breast cancer at Kenyatta national hospital, Kenya 

      Peter K Asaava (University of Nairobi, 2010)
      Haemostatic disorders (thrombosis and haemorrhage) are increasingly being investigated and assessed as factors that influence outcome of treatment of solid tumors including breast cancer. There is little data available on ...

    • Haemostatic disorders in patients with breast cancer at Kenyatta national hospital, Kenya 

      Peter K Asaava (University of Nairobi, 2010)
      Background Haemostatic disorders (thrombosis and haemorrhage) are increasingly being investigated and assessed as factors that influence outcome of treatment of solid tumors including breast cancer. There is little data ...

    • Haemostatic disorders in patients with breast cancer at Kenyatta national hospital, Kenya 

      Peter K. Asaava (University of Nairobi, 2010)
      Haemostatic disorders (thrombosis and haemorrhage) are increasingly being investigated and assessed as factors that influence outcome of treatment of solid tumors including breast cancer. There is little data available ...