Search
Now showing items 51-60 of 221
Modelling the Impact of Misdiagnosis and Treatment on the Dynamics of Malaria Concurrent and Co-infection with Pneumonia
(2013)
Incidences of misdiagnosis of diseases with similar symptoms as malaria has
increased lately due to the increasing levels of endemicity of these diseases and their co-
infection with malaria. In this paper a mathematical ...
Polymorphic variability in the 3'untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falc...
(BioMed Central, 2011-08-06)
Plasmodium falciparum malaria remains a leading cause of morbidity and
mortality among African children. Innate immunity provides the first line of defence against P.
falciparum infections, particularly in young children ...
Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating...
(Journals. ASm. org, 2012-10-08)
An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium
falciparum infection would aid in the designing of a rationally based malaria vaccine.
Variants within the Fc gamma receptors ...
Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya
(BioMed Central, 2011-04-20)
The appropriate use of anti-malarial drugs determines therapeutic efficacy and
the emergence and spread of drug-resistant malaria. Strategies for improving drug
compliance require accurate information about current ...
Bacteremia in Kenyan children presenting with malaria
(American Society for Microbiology, 2011-02-01)
Since the etiologies and clinical outcomes of bacteremia in children with
Plasmodium falciparum infections, particularly in areas of holoendemic malaria
transmission, are largely unexplored, blood cultures and comprehensive ...
Natural monocytic acquisition of haemozoin and rantes polymorphisms: association with malarial disease outcomes and functional changes in children from Wester...
(2011-08-15)
Plasmodium falciparum is an important cause of morbidity and mortality in children residing
in holoendemic transmission areas largely from severe malarial anaemia (SMA). Although
overproduction of inflammatory-derived ...
Communicating African spirituality through ecology: Challenges and prospects for the 21st century
(2012-06-19)
This review was set in the context of African spirituality and ecology. Specifically,
the review addressed issues of African spirituality and the environment from a Kenyan
context. Through analyses on existing literature, ...
Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV‐1
(Wiley Subscription Services, Inc., A Wiley Company, 2010-04-01)
Malaria and HIV-1 are coendemic in many developing countries, with anemia being
the most common pediatric hematological manifestation of each disease. Anemia is also
one of the primary causes of mortality in children ...
Turning point
(Nature Research, 2011-02-01)
Collins Ouma became a molecular biologist to help thwart malaria's high mortality rate in his
native Kenya. Last November, he won the Royal Society Pfizer award for his work on
identifying genes that may confer protection ...
Functional Haplotypes of Fc Gamma (Fcy) Receptor (FcyRIIA and FcyRIIB) Predict Risk to Repeated Episodes of Severe Malarial Anaemia and Mortality in Kenyan...
(SN Konah, 2012)
Development of protective immunity against Plasmodium falciparum is partially mediated
through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human
FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ...