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Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2012)
Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children
residing in regions where plasmodium falciparum transmission is holoendemic. Although
largely unexplored in children with SMA, ...
Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults
(Immunogenetics, 2012)
Polymorphic variability in immune response genes, such as IL12B, encoding the IL-12p40
subunit is associated with susceptibility to severe malaria in African populations. Since the
role of genetic variation in conditioning ...
Polymorphisms in Fc gamma receptor (FcγRIIIA-176 F/V) and Toll-like receptor (TLR9 [-1237 T/C]) are associated with protection against severe malarial anemia an...
(American Society for Microbiology, 2012-10-08)
Understanding the immunogenetic basis of naturally acquired immunity to
Plasmodium falciparum infection would aid in designing a rationally-based malaria vaccine.
Variants within the Fc gamma receptors (FcγRs) mediate ...
(− 7402 T/G and-4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels
(Bio Med Central, 2013)
In holoendemic Plasmodium falciparum transmission areas such as western Kenya, severe
malarial anemia [SMA, hemoglobin (Hb)< 6.0 g/dL, with any density parasitemia] is the most
common clinical manifestation of severe ...
Upregulation of Peripheral Blood Levels of Immune-Regulatory Interleukin-10 Cytokine in Human Immunodeficiency Virus-infected Compared to Non-infected Pregn...
(2012)
Alterations in the cytokine status have been suggested to be at least partly
responsible for the immune tolerance during pregnancy. Indeed, interleukin-10 (IL-10)
cytokine is known to control inflammationinduced ...
Social and Demographic Characteristics of HIV-Positive Mother-Infant Pair and Their Association with Mother-To-Child Transmission of HIV in Vihiga, Kakamega, Bu...
(2012)
The World Health Organization report indicates that in 2013~ 35
million people worldwide lived with HIV and AIDS. Of these, 3.2 million were children age<
15 years. The proportion of women living with HIV has remained ...
Dose-Effects of Bednets Impregnated with a Natural Pyrethrins Formulation: Persistence, Feeding Inhibition, and Wash Resistance against Anopheles gambiae ss
(2012)
This study evaluated dose-response, persistence, irritancy and wash
resistance of mosquito nets treated with a synergized natural pyrethrins-formulation against
Anopheles gambiae ss Methods. Multi-filament polyester ...
The Trends of Progesterone Hormone in Advancing Pregnancy of Human Immunodeficiency Virus-infected Women: A Cohort Study in Western Kenya
(2012)
Despite many studies on Human Immunodeficiency Virus (HIV) and pregnancy,
there is still insufficient information regarding the effect of HIV on progesterone in advancing
pregnancy. In a prospective cohort study, 44 ...
Effectiveness of Out-patient Therapeutic Program on Nutrition among Under Fives: A Retrospective Study of Kisumu East District, Kenya
(2013)
Abstract Outpatient Therapeutic Program (OTP) has been implemented with great success.
Monitoring and evaluation against program objectives is integral. This study aimed to assess
effectiveness of OTP program in Kisumu ...
Comparison of Different Trapping Methods to Collect Malaria Vectors Indoors and Outdoors in Western Kenya
(Research square, 2023-08-31)
Enhanced vector surveillance, is one of the 4 pillars of the WHO’s global vector control response (2017–2030). Human landing catches are the gold standard for entomological surveys but are difficult to implement and expose ...